<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09788

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMVQGVSVTGGGSVTPSSAITMPNAPNFHQSNPASPLSVMNTIGSPTQSGIDQPVGANVSPIKAAEFSSSAQLGTAARGDQSRRGAEASYLHHLSCRIILAGLEFNLKPATHAVIFQHMVNWLVNWDQRPQGMDETDTMQTCRLEKPLHEWMHLCLDVIWILVNEDKCRIPFYELVRCNLQFLENIPDDEALVSIIMEIHRRRDMVCMHMQMLDQHLHCPTFGTHRFLSQSYPSIAGESVTNLRYSPITYPSVLGEPLHGEDLANSIPKGGLDWERALRCLRHALRTTPSPDWWRRVLLVAPCYRSQSQQSSTPGAVFSPDMIGEAVADRTIELLKLTNSETQCWQDWLLFADIFFFLMKSGCIDFLDFVDKLASRVTNSDQQILRSNHVTWLLAQIIRIEIVMNTLSSDPRKVDTTRKIISFHKEDKSLDANNIGPQSILLDFISSSQTLRIWSFNTSIREHLNSDQLQKGKQIDEWWKQMMKASGERMIDFTNLDERATGMFWVLSFTMAQPACEAVMNWFTSAGMADLIQGPNMQPSERIMMMRETYPLSMSLLSGLSINLCLKLAYQLEETIFLGQAVPSIAMVETYVRLLLIAPHSLFRPHFTALTQRSPSILSKSGVSLLLLEILNYRLLPLYRYHGKSKALMYDVTKIISMIKGKRGEHRLFRLAENLCMNLILSLKDFFFVKKELKGPTEFTETLNRITIISLAITIKTRGIAEVEHMIYLQPLLEQIMATSQHTWSEKTLRYFPPLIRDFLMGRVDKRGLAIQAWQQAETTVINQCNQLLSPSAEPNYVMTYLSHSFPQHRQYLCAGAWMLMNGHLEINSANLARVLREFSPEEVTANIYTVVDVLLHHIQCEVQRGHLAQDLLSKAITNLSFFIWTHELLPLDILLLALIDRDDDPYALRLVISLLEKPELQQRVKNFCNTRSPEHWLKNQHPKRAELQKALGSHLSWKDRYPPFFDDIAARLLPVIPLIIYRLIENDATDIADRVLAFYSSLLAFHPLRFTFVRDILAYFYGHLPIKLIGRILNLLGVSTKTPFSESFAKYLVSSNSSICPPPEYFANLLLNLVNNVIPPLSSKSKSNPADTTRSTFNKHHASSQPGGVGNTDGQRAFYQNQDPGSYTQLVLETAAIEILSLPVPAAQIVSSLVQIIAHVQAILIQSNSGQGMSGGLGQSSGLPTSPSGAAESSGPNQANSAATGINATNFVSRSGYSCQQLSVLMIQACGLLLAQLPPEFHMQLYSEAARVIKDCWWLADGSRPVKELDSAVGYALLDPTWASQDNTSTAIGNIVALLHSFFSNLPQEWLESTHTVIKHLRPVNSVAMLRIAFRILGPLLPRLAFARPLFMKTLALLFNVLGDVFGKNPQVSNPNPVEASEIADIIDFLHHAVMYEGQGGPVQSTSKPKLEILTLCGKVIEILRPDVQHLLSHLKIDPTSSIYAATHPKLVQNPS
Length1456
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.08
Grand average of hydropathy-0.039
Instability index43.11
Isoelectric point6.87
Molecular weight163269.55
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09788
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.54|      42|     347|     226|     270|       1
---------------------------------------------------------------------------
  226-  270 (63.81/60.26)	FLSQSYPSIAgESVTNLRYSPITyPSVLGEPlHGEDLANSIP....KGG
  576-  621 (70.73/49.82)	FLGQAVPSIA.MVETYVRLLLIA.PHSLFRP.HFTALTQRSPsilsKSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.19|      39|     347|     354|     392|       2
---------------------------------------------------------------------------
  354-  392 (68.55/61.04)	FFFLMK..SGCIDFLDFVDKLAS...RVTNSDQQILRSNHVTWL
  685-  728 (55.64/47.77)	FFFVKKelKGPTEFTETLNRITIislAITIKTRGIAEVEHMIYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.34|      26|     347|     996|    1025|       3
---------------------------------------------------------------------------
  997- 1025 (39.17/32.67)	AFYSSLLaFHPLRFTFvrDILAYFYGHLP
 1345- 1370 (44.17/21.73)	AFARPLF.MKTLALLF..NVLGDVFGKNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.06|      14|      16|    1039|    1052|       7
---------------------------------------------------------------------------
 1039- 1052 (25.22/13.23)	STKTPFSESFAKYL
 1057- 1070 (27.84/15.35)	SSICPPPEYFANLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     216.12|      67|     534|     840|     907|      15
---------------------------------------------------------------------------
  840-  907 (112.59/95.71)	PEEVTA.NIYTVVDVLLHHIQCEVQRGHLaQDLLSKAITNLSFFIWTHELLPLDI..LLLAL.IDRDDDPYA
 1375- 1445 (103.53/82.39)	PNPVEAsEIADIIDFLHHAVMYEGQGGPV.QSTSKPKLEILTLCGKVIEILRPDVqhLLSHLkIDPTSSIYA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09788 with Med23 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSVTPSSAITMPNAPNFHQSNPASPLSVMNTIGSPTQSGIDQPVG
2) KSKSNPADTTRSTFNKHHASSQPGGVGNTDGQRAFYQ
11
1084
55
1120










Molecular Recognition Features






MoRF SequenceStartStop




NANANA