<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09783

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMDGGHTTRHPMSPAISASTVLPQQRQMQPHHHPARPAIADLFTLYLGMNSKQRAEDPLRESSNKLQKRVTALNRDLPPRDEQFISDYEQLRMQFPDAEQLQAITESVLISFVLQCSSHAPQSEFLLFATRCLCARGHLRWDSLLPSLLNTVSSIEAPMVQGVSVTGGGSVTPSSAITMPNAPNFHQSNPASPLSVMNTIGSPTQSGIDQPVGANVSPIKAAEFSSSAQLGTAARGDQSRRGAEASYLHHLSCRIILAGLEFNLKPATHAVIFQHMVNWLVNWDQRPQGMDETDTMQTCRLEKPLHEWMHLCLDVIWILVNEDKCRIPFYELVRCNLQFLENIPDDEALVSIIMEIHRRRDMVCMHMQMLDQHLHCPTFGTHRFLSQSYPSIAGESVTNLRYSPITYPSVLGEPLHGEDLANSIPKGGLDWERALRCLRHALRTTPSPDWWRRVLLVAPCYRSQSQQSSTPGAVFSPDMIGEAVADRTIELLKLTNSETQCWQDWLLFADIFFFLMKSGCIDFLDFVDKLASRVTNSDQQILRSNHVTWLLAQIIRIEIVMNTLSSDPRKVDTTRKIISFHKEDKSLDANNIGPQSILLDFISSSQTLRIWSFNTSIREHLNSDQLQKGKQIDEWWKQMMKASGERMIDFTNLDERATGMFWVLSFTMAQPACEAVMNWFTSAGMADLIQGPNMQPSERIMMMRETYPLSMSLLSGLSINLCLKLAYQLEETIFLGQAVPSIAMVETYVRLLLIAPHSLFRPHFTALTQRSPSILSKSGVSLLLLEILNYRLLPLYRYHGKSKALMYDVTKIISMIKGKRGEHRLFRLAENLCMNLILSLKDFFFVKKELKGPTEFTETLNRITIISLAITIKTRGIAEVEHMIYLQPLLEQIMATSQHTWSEKTLRYFPPLIRDFLMGRVDKRGLAIQAWQQAETTVINQCNQLLSPSAEPNYVMTYLSHSFPQHRQYLCAGAWMLMNGHLEINSANLARVLREFSPEEVTANIYTVVDVLLHHIQCEVQRGHLAQDLLSKAITNLSFFIWTHELLPLDILLLALIDRDDDPYALRLVISLLEKPELQQRVKNFCNTRSPEHWLKNLMFDICVTWHPYNKQFPLKKAVFF
Length1120
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.08
Grand average of hydropathy-0.134
Instability index45.43
Isoelectric point6.79
Molecular weight127690.14
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09783
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.66|      18|      22|     430|     447|       2
---------------------------------------------------------------------------
  430-  447 (34.54/20.61)	WERAL...RCLRHALRTTPSP
  450-  470 (30.12/17.04)	WRRVLlvaPCYRSQSQQSSTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.98|      22|      22|     172|     193|       3
---------------------------------------------------------------------------
  172-  193 (40.75/24.05)	PSSAITMPNAPNFHQSNPA..SPL
  195-  218 (34.23/19.06)	VMNTIGSPTQSGIDQPVGAnvSPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     189.33|      45|     634|     357|     401|       4
---------------------------------------------------------------------------
  357-  401 (83.84/60.54)	RRRDMVCMHMQML.DQHLHCPTFGTHRFLSQSYPSIAGESVTNLRY
  964- 1005 (64.78/44.89)	QHRQYLCAGAWMLmNGHLEINSANLARVLREFSP....EEVTANIY
 1008- 1038 (40.71/25.12)	.........VDVL.LHHIQCEVQRGH..LAQ...DLLSKAITNLSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.60|      53|     634|      32|     124|       5
---------------------------------------------------------------------------
   38-   92 (86.74/103.01)	IADLFTLYLGMN...SKQRAEDPLRE..SSNKLQKRVTALNrdLPPRD..EQFISDYEQLRM
  550-  609 (74.86/26.90)	LAQIIRIEIVMNtlsSDPRKVDTTRKiiSFHKEDKSLDANN..IGPQSilLDFISSSQTLRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.22|      25|     295|     610|     634|       6
---------------------------------------------------------------------------
  610-  634 (47.34/28.71)	WS......FNTSIREHLNSDQLQKGKQIDEW
  900-  930 (41.88/24.57)	WSektlryFPPLIRDFLMGRVDKRGLAIQAW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.90|      11|      23|     298|     311|       7
---------------------------------------------------------------------------
  298-  311 (17.26/19.73)	CRLekPLHEWMHlC
  324-  334 (23.65/13.12)	CRI..PFYELVR.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.86|      10|      16|     659|     668|       9
---------------------------------------------------------------------------
  659-  668 (20.76/10.68)	MFWVLSFTMA
  676-  685 (21.10/10.96)	MNWFTSAGMA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09783 with Med23 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDGGHTTRHPMSPAISASTVLPQQRQMQPHHHP
1
33










Molecular Recognition Features






MoRF SequenceStartStop




1) LFTLYLGM
41
48