<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09773

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMDGGHTTRHPMSPAISASTVLPQQRQMQPHHHPARPAIADLFTLYLGMNSKQRAEDPLRESSNKLQKRVTALNRDLPPRDEQFISDYEQLRMQFPDAEQLQAITESVLISFVLQCSSHAPQSEFLLFATRCLCARGHLRWDSLLPSLLNTVSSIEAPMVQGVSVTGGGSVTPSSAITMPNAPNFHQSNPASPLSVMNTIGSPTQSGIDQPVGANVSPIKAAEFSSSAQLGTAARGDQSRRGAEASYLHHLSCRIILAGLEFNLKPATHAVIFQHMVNWLVNWDQRPQGMDETDTMQTCRLEKPLHEWMHLCLDVIWILVNEDKCRIPFYELVRCNLQFLENIPDDEALVSIIMEIHRRRDMVCMHMQMLDQHLHCPTFGTHRFLSQSYPSIAGESVTNLRYSPITYPSVLGEPLHGEDLANSIPKGGLDWERALRCLRHALRTTPSPDWWRRVLLVAPCYRSQSQQSSTPGAVFSPDMIGEAVADRTIELLKLTNSETQCWQDWLLFADIFFFLMKSGCIDFLDFVDKLASRVTNSDQQILRSNHVTWLLAQIIRIEIVMNTLSSDPRKVDTTRKIISFHKEDKSLDANNIGPQSILLDFISSSQTLRIWSFNTSIREHLNSDQLQKGKQIDEWWKQMMKASGERMIDFTNLDERATGMFWVLSFTMAQPACEAVMNWFTSAGMADLIQGPNMQPSERIMMMRETYPLSMSLLSGLSINLCLKLAYQLEETIFLGQAVPSIAMVETYVRLLLIAPHSLFRPHFTALTQRSPSILSKSGVSLLLLEILNYRLLPLYRYHGKSKALMYDVTKIISMIKGKRGEHRLFRLAENLCMNLILSLKDFFFVKKELKGPTEFTETLNRITIISLAITIKTRGIAEVEHMIYLQPLLEQIMATSQHTWSEKTLRYFPPLIRDFLMGRVDKRGLAIQAWQQAETTVINQCNQLLSPSAEPNYVMTYLSHSFPQHRQYLCAGAWMLMNGHLEINSANLARVLREFSPEEVTANIYTVVDVLLHHIQCEVQRGHLAQDLLSKAITNLSFFIWTHELLPLDILLLALIDRDDDPYALRLVISLLEKPELQQRVKNFCNTRSPEHWLKNQHPKRAELQKALGSHLSWKDRYPPFFDDIAARLLPVIPLIIYRLIENDATDIADRVLAFYSSLLAFHPLRFTFVRDILAYFYGHLPIKLIGRILNLLGVSTKVNLYPLFRIFC
Length1209
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.08
Grand average of hydropathy-0.100
Instability index44.86
Isoelectric point7.13
Molecular weight137858.96
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09773
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     330.34|     104|     295|     591|     707|       1
---------------------------------------------------------------------------
  591-  707 (159.26/177.27)	IGPQSILLDFISSSQtlRIWS......FNTSIREHLNSDQLQKGKQIDEWwkQMMKASgerMIDFTN..LDERATGMFWVLSFTMAQPACEAVM...NWFTSAGMADlIQGPNMqpsERImmMRETYP
  883-  997 (171.08/139.08)	IYLQPLLEQIMATSQ..HTWSektlryFPPLIRDFLMGRVDKRGLAIQAW..QQAETT...VINQCNqlLSPSAEPNYVMTYLSHSFPQHRQYLcagAWMLMNGHLE.INSANL...ARV..LREFSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.54|      42|     347|     383|     427|       2
---------------------------------------------------------------------------
  383-  427 (63.81/55.70)	FLSQSYPSIAgESVTNLRYSPITyPSVLGEPlHGEDLANSIP....KGG
  733-  778 (70.73/46.05)	FLGQAVPSIA.MVETYVRLLLIA.PHSLFRP.HFTALTQRSPsilsKSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.88|      60|     178|      10|      69|       3
---------------------------------------------------------------------------
   10-   69 (105.85/62.51)	PMSPAISASTV.LPQQRQM.QPHHHPARPAIADLFTLYLGMNSKQRAEDPLR..ESS..NKLQKRV
  189-  254 (84.03/48.19)	PASPLSVMNTIgSPTQSGIdQPVGANVSPIKAAEFSSSAQLGTAARGDQSRRgaEASylHHLSCRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.66|      18|      23|     430|     447|       4
---------------------------------------------------------------------------
  430-  447 (34.54/22.02)	WERAL...RCLRHALRTTPSP
  450-  470 (30.12/18.20)	WRRVLlvaPCYRSQSQQSSTP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.43|      14|      23|     298|     313|       5
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  298-  313 (25.48/19.52)	CRLekPLHEWMHLCLD
  324-  337 (27.95/15.16)	CRI..PFYELVRCNLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.62|      29|     883|     123|     152|       9
---------------------------------------------------------------------------
  123-  152 (48.97/36.90)	EFLLFATRCLCARGHLRWDsLLPSLLNTVS
 1009- 1037 (50.65/33.36)	DVLLHHIQCEVQRGHLAQD.LLSKAITNLS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09773 with Med23 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDGGHTTRHPMSPAISASTVLPQQRQMQPHHHP
1
33










Molecular Recognition Features






MoRF SequenceStartStop




1) LFTLYLGM
41
48