<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09710

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMEEGNVRVDLDKLPIKRLEAIEETGNEHYPPDTSNEEQRLAAIRRIDFSWVIEKDAKKAKKAAEADTAQQAWPWQGLMESLQQAHQELSVVIDLIGTVEANDAVAVASTTKPKSQPNEILVDMAVSAATKLQRLRHLSWYFKQSAKTMEQQFQKETRFYGSLIRCCHKVLRLQQNWKVKRQRAVGSPGSEGFMFDLVDSSQLDTTTVLRLSPLSLIPIDQDSSGTLSVQIPQKSLRSLSLKFHGDIVNNAESSAIKKKEGTLTNTTAEAEKDVLADDDVNKSIRYAHSILRDIHKSIFEEQVFDMVIRETFNQSQGINVTGMCEDFLQLAIGQECSLCLSLELSGQNNNAGTVGQQDHMDTNYPGNLAVATVNGKESSNKDVRGFPNPKSLEIYLLHMFHEILRKLREKSRHVVRYQSSAQAAPDDCGLLSHFCMTVAHRIFSNKVHLELESVVSRVPYLHLRSLPTWHSRTSSWSLCLKVPQPILATGRVTKPSDYHELKYKSRSQFSTKVILKDGQISLMGEGSPSIVGSLTGKPSDSRLINSYNCDLEDLPMMLLQQVASQVIHWLHDEAMILGMNVTRDFLCLYFDLGQGETLGLLAHVDPDDTYGCISWYLTVEHPMEEGKMSAGSPESEKRRFLGYLSLEVLYSTLMDLIKLCSTSDQIRAS
Length668
PositionHead
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.07
Grand average of hydropathy-0.353
Instability index44.80
Isoelectric point6.05
Molecular weight74990.47
Publications
PubMed=19965430

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09710
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.03|      34|      35|     109|     143|       1
---------------------------------------------------------------------------
  109-  143 (52.63/36.38)	TTKPKSQPNEILVDMAVSAATKLQRLRHlSWYFKQ
  147-  180 (60.40/37.74)	TMEQQFQKETRFYGSLIRCCHKVLRLQQ.NWKVKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     173.36|      56|      98|     226|     284|       4
---------------------------------------------------------------------------
  226-  284 (81.02/61.95)	LSVQIPQKSLRSLSLKFHGDiVNNAesSAIKKKEGTLTNTTAE.AEKDVLADDDVNKSIR
  327-  383 (92.34/59.95)	LQLAIGQECSLCLSLELSGQ.NNNA..GTVGQQDHMDTNYPGNlAVATVNGKESSNKDVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.35|      24|      41|       7|      30|       6
---------------------------------------------------------------------------
    7-   30 (41.65/28.78)	RVD....LDKLPIKRLEAIE.ETGNEHYP
   45-   73 (30.70/19.48)	RIDfswvIEKDAKKAKKAAEaDTAQQAWP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09710 with Med17 domain of Kingdom Viridiplantae
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