<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09676

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMAAADRQLVVAVEGTAALGPYWSTIVAEYVEKIVRSFCASELPGQKLVGTPPELALVVFHTHGPYSAFDVQRSGWTKDVDAFLSWLSGILFSGGGFSEASTCEGLAEALKILQGNPNTTQGHQNHEAQKHCILVAASNPYPLPTPVYCLPTQSTDHKENIETSKEPSIADAETVAKSFAQCSVSLSVISPKQLPTLKAIYNAGKRNLRAADPSVDHAKNPHFLVLLSENFMEARTALSRPLHGNLAPNQTITKMDTAPAVTMPGPTSNGNSSVNAMAGRQPIVGGISTTSVKVEPTTMPPIVSAPAFSHVTPISNVASQGISALQTSSPSLISQEANMGNDNVQEHKPIINPVQQPIRPGGHGSLLNNLSQVRLMNSTSLGGGATSMGLPNMGATPIQVHMSNMISSGMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTPTVTGNSTIAVSSSLTNNQSSMGMGQSVQSVAQGGLVSGSQLGQGGIVANQNVMSTLGPTAISSTPAMMPTPGMVPQTGVNSLGVNNNSAMNMPITQQHANAQQPPPKYVKIWELYLAKGKDSL
Length568
PositionUnknown
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.04
Grand average of hydropathy-0.128
Instability index40.56
Isoelectric point6.92
Molecular weight59131.32
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP09676
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     161.42|      26|      74|     347|     372|       1
---------------------------------------------------------------------------
  299-  310 (20.51/ 6.62)	PPI...VSAP..................AFSHV
  311-  341 (32.34/14.99)	TPISNVASQGISalQT..SSPSLISqeaNMGND
  347-  372 (45.10/24.02)	KPIINPVQQPIR..PG..GHGSLLN...NLSQV
  395-  420 (31.44/14.36)	TPIQVHMSNMIS..SGmtSTPSVIS...SMS..
  425-  447 (32.03/14.77)	.PI..STQQMVQ..ST..ALGSFGS...NTPTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.84|      23|      43|     460|     487|       2
---------------------------------------------------------------------------
  460-  482 (40.14/15.01)	TNNQSSMGMGQSVQSVAQGGLVS
  504-  526 (40.70/19.00)	TAISSTPAMMPTPGMVPQTGVNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.81|      43|      49|     139|     186|       4
---------------------------------------------------------------------------
  139-  186 (64.43/62.27)	PYPLPTpvycLPTQSTDHKENIETSkEPSIADAET......VAKSFAQCSVSLS
  190-  238 (66.38/46.35)	PKQLPT....LKAIYNAGKRNLRAA.DPSVDHAKNphflvlLSENFMEARTALS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP09676 with Med25 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ALSRPLHGNLAPNQTITKMDTAPAVTMPGPTSNGNSSVNAMAGRQP
2) GMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTPTVTGNSTIAVSSSLTNNQSSMGMGQSVQS
3) GPTAISSTPAMMPTPGMVPQTGVNSLGVNNNSAMNMPITQQHANAQQ
4) LQTSSPSLISQEANMGNDNVQEHKPIINPVQQPIRPGGHGSLLNNLSQV
5) NSTSLGGGATSMGLPNMGATPIQVHMSNMIS
236
408
502
324
376
281
474
548
372
406

Molecular Recognition Features

MoRF SequenceStartStop
1) PKYVKIWELYLAKGKDSL
551
568