<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09674

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMAAADRQLVVAVEGTAALGPYWSTIVAEYVEKIVRSFCASELPGQKLVGTPPELALVVFHTHGPYSAFDVQRSGWTKDVDAFLSWLSGILFSGGGFSEASTCEGLAEALKILQGNPNTTQGHQNHEAQKHCILVAASNPYPLPTPVYCLPTQSTDHKENIETSKEPSIADAETVAKSFAQCSVSLSVISPKQLPTLKAIYNAGKRNLRAADPSVDHAKNPHFLVLLSENFMEARTALSRPLHGNLAPNQTITKMDTAPAVTMPGPTSNGNSSVNAMAGRQPIVGGISTTSVKVEPTTMPPIVSAPAFSHVTPISNVASQGISALQTSSPSLISQEANMGNDNVQEHKPIINPVQQPIRPGGHGSLLNNLSQVRLMNSTSLGGGATSMGLPNMGATPIQVHMSNMISSGMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTPTVTGNSTIAVSSSLTNNQSSMGMGQSVQSVAQGGLVSGSQLGQGGIVANQNVMSTLGPTAISSTPAMMPTPGMVPQTGVNSLGVNNNSAMNMPITQQHANAQQPPPKYVKIWEGYRSGTASETLAADWPETMQIVRLIAQEHMNNKQYVGKADFLVFRTLNHHGFLVQLQEKKLCAVIQLPSQTLLLSMADKAGRLIGMLFPGDMVVFKPQASTQQTPMQQQQLQQFQQQQQQLQQHMHMQPQGLPLQQSQMQLQQQQPQMQPMQQQQPSQMQQQMQSMQQQMQPMQQQMQHQQQQMQHQQQQMQQMQQQQQQQQQQQQQIQPQQQQMQQMQQQQQQQMQPQQQQMQQMQQQQQQMQPQQQQMQQMQQQQQQMQPQQQQQPQMVGTGMGQQFMQGHNRAVQMMQGKITPQGPGSMPGGGFLP
Length867
PositionUnknown
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.04
Grand average of hydropathy-0.524
Instability index54.66
Isoelectric point8.16
Molecular weight94387.00
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09674
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     182.84|      16|      16|     784|     799|       1
---------------------------------------------------------------------------
  736-  752 (35.48/ 7.69)	QHQQQ.qMQHQQQQMQQM
  760-  776 (35.81/ 7.84)	QQQQQ.qIQPQQQQMQQM
  777-  794 (38.14/ 8.84)	QQQQQqqMQPQQQQMQQM
  795-  811 (38.54/ 9.01)	QQQQQ.qMQPQQQQMQQM
  812-  828 (34.88/ 7.44)	QQQQQ.qMQPQQQQQPQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     218.01|      42|      44|     227|     268|       2
---------------------------------------------------------------------------
  178-  215 (29.64/ 8.33)	...FAQCSVSLS.....VIS.......PKQ.....LPTLKAIYNAGkrnlraadPSVD
  227-  268 (71.70/29.44)	SENFMEARTALSRPLHGNLA.......PNQ.TITKMDTAPAVTMPG........PTSN
  272-  315 (57.78/22.45)	SVNAMAGR....QPIVGGISttsvkvePT..TMPPIVSAPAFSHVT........PISN
  377-  418 (58.88/23.00)	STSLGGGATSMGLPNMGA.T.......PIQvHMSNMISSGMTSTPS........VISS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.95|      16|      19|     693|     711|       3
---------------------------------------------------------------------------
  679-  698 (29.66/ 6.41)	LQQHM.HMQP..QglplQQSQMQ
  699-  718 (22.29/10.92)	LQQQQpQMQPmqQ...qQPSQMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     190.23|      48|     127|     320|     368|       4
---------------------------------------------------------------------------
  320-  365 (67.62/31.32)	................GISALQTSSpSLISQEANMGNDNVQEHKPIINPVQQPIRPGG..HGSL
  441-  485 (50.49/18.14)	GSN........tptvtGNSTIAVSS.SLTNNQSSMG..........MGQSVQSVAQGGlvSGSQ
  486-  527 (39.53/12.17)	LGQggivanqnvmstlGPTAISST....................PAMMPTPGMVPQTG..VNSL
  833-  859 (32.59/ 8.17)	..................................MGQQFMQGHNRAVQMMQGKITPQG..PGS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.91|      12|      42|     539|     554|       6
---------------------------------------------------------------------------
  539-  554 (17.39/18.03)	ITQQHANAQQpppkYV
  583-  594 (23.53/10.76)	IAQEHMNNKQ....YV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09674 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALSRPLHGNLAPNQTITKMDTAPAVTMPGPTSNGNSSVNAMAGRQP
2) GMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTPTVTGNSTIAVSSSLTNNQSSMGMGQSVQSVAQGGL
3) LQTSSPSLISQEANMGNDNVQEHKPIINPVQQPIRPGGHGSLLNNLSQV
4) NSTSLGGGATSMGLPNMGATPIQVHMSNMIS
5) QIQPQQQQMQQMQQQQQQQMQPQQQQMQQMQQQQQQMQPQQQQMQQMQQQQQQMQPQQQQQPQMVGTGMGQQFMQGHNRAVQMMQGKITPQGPGSMPGGGFLP
6) QQQLQQHMHMQPQGLPLQQSQMQLQQQQPQMQPMQQQQPSQMQQQMQSMQQQMQPMQQQMQHQQQQMQHQQQQMQQM
236
408
324
376
765
676
281
480
372
406
867
752










Molecular Recognition Features






MoRF SequenceStartStop




NANANA