<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09664

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMDSLAIPYVEEVGLRRPSSNLWLRLPFAQDDSWNHICLRLGKAGSMSWDVRINDPHFRELWELNGGSTKTQWGVGIRIANSSEMDSHISFDSSGVVLTYNTVEADSVQKLVSDLRRLSNARSFALGMRRLIGVKFQDKLDDNQLTMEVKSQSVNKGNSDAADKLSEQMRKTFRIEAVGLMSLWFSYGTMPMVHIVVEWEIAKAGCTMHVSPDQLWPHTKFLEDFVNGGEVASFLDCIRLTAGPLLALGGAIRPARMPVAVSSGYSSMPKQPNIPTQGPLVNGSSSTIHHAPGPSNAASAHLGSHNLHAAAMLSAVGRGGPGLVPSSLLPFDVSVVLRGPYWIRIIYRKKFSVDMRCFAGDQVWLQPATPPKGGPSVGGSLPCPQFRPFIMEHVAQGLNALEPNFMNATQASGHLNNNAGVPQTAPSANRLNATPGVSMVRPTSGVANHVAASLSRAGNAMLASSALASGISGTSVRLTAGAGLPVHMKGELNTAFIGLGDDGGYGGGWVPLAALKKVLRGILKYLGVLWLFAQLPELLKEILGSILKDNEGALLNLDQEQPALRFYVGGYVFAVSVHRVQLLLQVLSVKRFHHQQQQQQAQSNAQEELAAVEINEICDYFSRRVASEPYDASRVASFITLLTLPILVLREFLKLITWKKGLSPVHGDIATAQRARIELCLENHSGSASSDNTENSSLAKSNIHHDRAHSSVEFALTFVLDHALIPHMNVAGGAAWLPYCVSVKLRYSFGDNNHIAFLAMNGSHGGRACWLQFEEWERCKQKVSRAVETVNGSGVAGEVGQGRLRMVAEMIQKQLQLCLQQLRDDPLSAGSTAS
Length833
PositionTail
OrganismZea mays (Maize)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Tripsacinae> Zea.
Aromaticity0.07
Grand average of hydropathy-0.071
Instability index47.97
Isoelectric point8.63
Molecular weight90327.26
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09664
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     613.13|     162|     164|     183|     344|       1
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  183-  286 (155.43/95.46)	..........................................................................................WFSYGTMPMVHIVVEWEIAKAGCTMHVSPDQLWPHTKF.LEDF.....V..........................................................NGGEVASFLDCIRLT.......AGPLLALGGAIRPARMPVAVSSGYSSMPKQPNIPTQGPLVN.....GSSST
  287-  438 (213.16/134.18)	IHHAPGPSNAASAHL...GSHNLHAAAMLSAVGRGGPGLVPSSLLPFDVSVVLR.........GPY...WIRI.............iyrkKFSVDMRCF...........AG.......DQVWLQPAT.PPK.................................................................GGPSVGGSLPCPQFRpfimehvAQGLNAL....EPNFMNATQASGH..LNNNAGVPQTAPSANrlnatPGVSM
  439-  571 (89.90/51.51)	VRPTSGVANHVAASLsraGNAMLASSALASGISGTSVRLTAGAGLPVHMKGELNtafiglgddGGYgggWVPLaalkkvlrgilkylgvlWL.FAQLPELLKEILGSILKDNEGALLNLDQEQPALRFyVGGY.....V...................................................................................................................................
  630-  687 (41.09/18.76)	...........................................................................................................................................favsvhrvqlllqvlsvkrfhhqqqqqqaqsnaqeelaaveineicdyfsrrvasepyDASRVASF...ITLL.......TLPILVLREFLKLITWKKGLSPVHGDIATAQRARIELCLEN.....HSGSA
  702-  803 (113.54/67.36)	IHHDRAHSSVEFALT...FVLD.HALIPHMNVA.GG.....AAWLPYCVSVKLR...........Y...SFGD........nnhiaflamNGSHGGRACWLQFEEWE....RCKQKVS...............ravetV..........................................................NGSGVAGEVGQGRL...........................................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.93|      26|      36|      20|      46|       2
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   20-   46 (43.33/30.20)	NLWLRLPFAQDDSWNhICLRLGKAGSM
   59-   84 (45.60/26.77)	ELWELNGGSTKTQWG.VGIRIANSSEM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09664 with Med14 domain of Kingdom Viridiplantae
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