<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09628

Description Mediator of RNA polymerase II transcription subunit 19
SequenceMKITNARHRDSAGAEGTMENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPPGGGPGTAPPPTAATAPPGADKSGAGCGPFYLMRELPGSTELTGSTNLITHYNLEQAYNKFCGKKVKEKLSNFLPDLPGMIDLPGSHDNSSLRSLIEKPPILSSSFNPITGTMLAGFRLHTGPLPEQCRLMHIQPPKKKNKHKHKQSRTQDPVPPETPSDSDHKKKKKKKEEDPERKRKKKEKKKKKNRHSPDHPGMGSSQASSSSSLR
Length261
PositionHead
OrganismMacaca mulatta (Rhesus macaque)
KingdomMetazoa
Lineage
Aromaticity0.04
Grand average of hydropathy-1.030
Instability index61.96
Isoelectric point9.86
Molecular weight28109.76
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09628
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.11|      16|      16|      31|      46|       1
---------------------------------------------------------------------------
   31-   46 (36.40/11.13)	PPPPPTALGFGPGKPP
   48-   63 (37.71/11.78)	PPPPPPGGGPGTAPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     127.82|      32|     115|     116|     147|       2
---------------------------------------------------------------------------
   84-  100 (21.56/ 7.50)	..........LMRELPGSTELTGSTN......L
  116-  147 (58.86/31.94)	KKVKEKLSN.FLPDLPGMIDLPGSHDNSSLRSL
  232-  260 (47.40/24.43)	KKEKKKKKNrHSPDHPGM....GSSQASSSSSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.86|      16|      18|     187|     202|       3
---------------------------------------------------------------------------
  187-  202 (28.50/12.57)	PPK...KKNKHKHKQSRTQ
  206-  224 (21.35/ 7.85)	PPEtpsDSDHKKKKKKKEE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09628 with Med19 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FLPDLPGMIDLPGSHDNSSLRSLIEKPPILSSSFNPIT
2) MKITNARHRDSAGAEGTMENFTALFGAQADPPPPPTALGFGPGKPPPPPPPPPGGGPGTAPPPTAATAPPGADKSGAGCGPFY
3) TMLAGFRLHTGPLPEQCRLMHIQPPKKKNKHKHKQSRTQDPVPPETPSDSDHKKKKKKKEEDPERKRKKKEKKKKKNRHSPDHPGMGSSQASSSSSLR
125
1
164
162
83
261










Molecular Recognition Features






MoRF SequenceStartStop




1) DSDHKKKKKKKEEDPERKRKKKEKKKKKNRHSPDH
2) MENFTALFGA
212
18
246
27