<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09597

Description Mediator complex subunit 25
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTENLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAAPSAVPCGAVGPWSSPVPFLLPFYPQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRCESWGENEGAGRGQAGLPPHTCSSLLPLVSPTVSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMVGACTPPAPTPSSCCPQLGQLEDESFAFQGGVDLVALGPWGFVVRVLQMPEMRVWGRNGEAHGSRWVRAVLRNPRNPWVWESGASHSLRVLESCSIQAFRVLGLAKCCSGNG
Length514
PositionUnknown
OrganismMacaca mulatta (Rhesus macaque)
KingdomMetazoa
Lineage
Aromaticity0.07
Grand average of hydropathy-0.025
Instability index58.10
Isoelectric point5.94
Molecular weight53555.66
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09597
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.53|      29|      30|     185|     213|       1
---------------------------------------------------------------------------
  185-  208 (30.52/ 7.34)	....................PRKL.PAL......RLLFEKAAPPALLEPLQ
  209-  240 (38.37/11.16)	PPTDV............sqdPRHM.VLV......RGLVLPVGGGSAPGPLQ
  304-  345 (30.69/ 7.42)	PRCESwgenegagrgqaglpPHTC.SSL......LPLVSPTVSP..ITPLQ
  408-  443 (35.95/ 9.98)	PPAPT...............PSSCcPQLgqledeSFAFQGGVDLVALGPWG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.27|      15|      19|     368|     382|       3
---------------------------------------------------------------------------
  241-  255 (27.32/ 8.10)	PKQPVPLPPAAPSAV
  257-  271 (25.20/ 6.89)	CGAVGPWSSPVPFLL
  368-  382 (29.74/ 9.47)	PGAPKPPPASQPSLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.82|      31|     110|      39|      69|       4
---------------------------------------------------------------------------
   39-   69 (58.34/32.61)	YLLPAIEYFNGGPPAETDFGGDYG..GTQYSLV
  151-  183 (50.47/27.26)	YLLPAVESTTYSGCTTENLVQQIGerGIHFSIV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.88|      20|      22|     444|     464|       6
---------------------------------------------------------------------------
  444-  464 (34.16/24.19)	FVVRVLQMP.EMRVWgRNGEAH
  468-  488 (36.73/21.10)	WVRAVLRNPrNPWVW.ESGASH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.17|      10|      19|     293|     302|       7
---------------------------------------------------------------------------
  293-  302 (16.95/ 8.62)	EAAKNQKAGL
  313-  322 (18.22/ 9.76)	EGAGRGQAGL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09597 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQVAAQNAVEAAKNQKAGLGPRCESWGENEGAGRGQAGLPPHTCSS
2) VSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMVGACTP
284
338
329
408










Molecular Recognition Features






MoRF SequenceStartStop




NANANA