<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09573

Description Uncharacterized protein
SequenceMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAATAATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNSGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPTGPGTSNPNSNIMLASASFDSTVRLWDVDRGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGTLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length523
PositionTail
OrganismGallus gallus (Chicken)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Phasianidae> Phasianinae> Gallus.
Aromaticity0.07
Grand average of hydropathy-0.298
Instability index35.92
Isoelectric point5.40
Molecular weight56585.36
Publications
PubMed=15592404

Function

Annotated function 
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central

GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central

GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09573
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     366.55|      40|      40|     331|     370|       1
---------------------------------------------------------------------------
  174-  207 (40.15/17.20)	..LRGHESE...........VFICAWNPVS.........dlL.ASGS.GDSTARIWNL.......
  233-  268 (39.56/16.85)	.S....NKD...........VTSLDWNSDG.........tlL.ATGS.YDGFARI.WT.EDGNLA
  269-  299 (39.23/16.66)	STLGQHKGP...........IFALKWNKKG..........nY............ILSA.GVDKTT
  300-  351 (52.12/24.24)	IIWDAHTGEakqqfpfhsapALDVDWQNNT..........tF.ASCS.TDMCIHVCRL.GCDRPV
  352-  393 (62.61/30.40)	KTFQGHTNE...........VNAIKWDPSG.........mlL.ASCS.DDMTLKIWSM.KQDTCV
  394-  442 (47.18/21.33)	HDLQAHSKE...........IYTIKWSPTGpgtsnpnsnimL.ASAS.FDSTV...RLwDVDRGV
  445-  486 (58.12/27.76)	HTLTKHQEP...........VYSVAFSPDG..........kYlASGS.FDKCVHIWNT.QSGTLV
  487-  518 (27.57/ 9.80)	HSYRG.TGG...........IFEVCWNARG........dkvG.ASASdGSVCV............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.35|      22|      22|     127|     148|       2
---------------------------------------------------------------------------
  127-  148 (36.10/24.02)	AVSQQNTPKNGEATVNGEENGA
  150-  171 (38.25/25.87)	AINNHSKPMEIDGDVEIPPNKA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09573 with Med16 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATAGTTTTAVSQQNTPKNGEATVNGEENGAHAINNHSKPMEIDGDVEIPPNKAT
119
172










Molecular Recognition Features






MoRF SequenceStartStop




NANANA