<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09566

Description Mediator complex subunit 23
SequenceVFLLQKTEVIEEAFPGMFMDTPEDERTKLISCLGAFRQFWSSLSQESHEQCVQWIVRFIHSQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLIRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVVAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAMCNSWKLDPTTLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYCAHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAHSDNSKLQIPIPHSLKHHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGVLVETIYGNGNMRISLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQRNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPAPLQVFFKQNNVPQESRFNLKKNVEEEYRKWKSMTNENEIITRFSVQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMSYHKKYPEKLYFEGLAEQVNPPVQIQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRERTNLKRKLVHAIIGSLKDNRPLGWCLSDTYLKCAMNAREDNPWVPDDTYYCKLIGRLVDNILLSKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVPGTDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDHIVSVINSPSLTSETEWVGYPFQLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLIPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYEMLLNADQYSSHLNYMDPICDFLYHMKYMFTGDSVKDQVEKIICNLRPALKLRLRFITHISKMEPAGVPQQPLSNGSPAQQASQVPVNVALPVTQ
Length1368
PositionTail
OrganismGallus gallus (Chicken)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Phasianidae> Phasianinae> Gallus.
Aromaticity0.10
Grand average of hydropathy-0.010
Instability index45.82
Isoelectric point7.60
Molecular weight156724.45
Publications
PubMed=15592404

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09566
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.14|      14|      17|    1039|    1055|       1
---------------------------------------------------------------------------
 1039- 1053 (25.22/20.55)	WCLSDTYLkCAMNAR
 1058- 1071 (29.93/12.95)	WVPDDTYY.CKLIGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.35|      15|      17|     249|     265|       2
---------------------------------------------------------------------------
  235-  254 (23.88/12.37)	LDPTT..LRFPlkgllPYDKDL
  255-  274 (20.48/16.03)	FEPQTalLRYV..leqPYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.20|      16|      17|     992|    1007|       3
---------------------------------------------------------------------------
  992- 1007 (31.52/24.89)	YKFHDRPVTYLYNTL.H
 1009- 1025 (24.68/17.58)	YERHLRERTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     257.16|      81|     258|     284|     368|       4
---------------------------------------------------------------------------
  284-  368 (137.70/93.70)	QVLYCAHKQRCPVLEDQLVD....LVVYAmersETEEKFDDGGTSQLLWQHLSSQL..IFFVLFQFASF......PHMVLSLHQKLAGRGLIKGRDH
  543-  635 (119.47/72.72)	RVIKLAHAKSSVALAPALVEtysrLLVYM....EIESLGIKGFISQLLPTVFKSHAwgILHTLLEMFSYrmhhiqPHYRVQLLSHLHSLAAVPQRNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.30|      11|      18|     405|     416|       5
---------------------------------------------------------------------------
  405-  416 (17.59/13.33)	CIPVpDIN.KPQS
  424-  435 (18.71/ 8.47)	CIWI.HLNrKAHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.88|      10|      28|     127|     136|       6
---------------------------------------------------------------------------
  127-  136 (15.58/ 9.83)	RDLLKVILEK
  156-  165 (16.30/10.63)	REVVAYILER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.35|      27|     679|      21|      47|       7
---------------------------------------------------------------------------
   21-   47 (49.24/33.31)	TPEDERTKLISCLGA.....FRQF....WSSLSQES
  720-  749 (40.78/26.11)	TPHNWASHTLSCFPAplqvfFKQ......NNVPQES
  768-  794 (28.34/15.53)	TNENEIITRFSVQGS.....PPLFlcllWKML....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.66|      16|      19|     929|     944|       8
---------------------------------------------------------------------------
  929-  944 (28.03/16.96)	LYFEGLAEQVNPPVQI
  951-  966 (29.64/18.38)	IYFGNVCLRFLPVFDI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09566 with Med23 domain of Kingdom Metazoa
Unable to open file!