<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09558

Description Uncharacterized protein
SequenceMYSSQNNSRLHRKVQNYRQTRSSNAASALVSRRNAIRKENPFSELLNLRYSLNSPHPDVFPLSGIAEPLSLLLTNPFEDYSNNIKRFSQAHLQNDLSDVNAYDTFLSSSSSPVSSPAFLNSRKRPLPDNYSDVYYTIYPDFIPWHHTPIEDSITSSHLDKGFVEPSPIRNELASAASLVIHLKNLNDLSNNLLQLKIVRDNYYDKIIDNSSFQPPSRVTLTDSKREAWLRDLASINIPLKNLAEKKIPYGIKNRVLIDQIILKRVPISRAIWLIKCVGLNELKIIKRKQNLPINSYQLWINEWTSHLTFYLDNILSQYSNAFFNSSSKNININDQSNTTTFNNNNSNYNNNSTIDEKLLDYLSLNLISSLKYKISYIINLIFNLFYEKLINRNIFFNWLINSFKKVEKEFELILLLQLIKIFSKFLIPNIINNNTNNTNNTNNTNNTNNTNNTNNTNNTNNINTSTSDLSPENTDILLSSLFQILIFKYDFILNKLSLKNLSTNQNFNPNTSVQQNYSNINTPNNNNNNNNTNTNNNKFYFSNNSIYSQVNSPTTFGNSPINFNYSSNLDSFSKIIDDASKVNKELNLKKLSMLYDIKNLINFLFLKKSDWLIIQKIDQLSLKTWNDTKNFLIKYDILDIQLKPKNKLDYKNIQSLINPDSKINSDFNITFNDVNYYYYLKKNFNFQSLNFDEILILLKKERFNEICFKNDCLLKPLKQNKDDDSDTDTQTNTLDFDLILNRRNLTNNELLLQKLNDFLNKRDFFLQSFICHDQEIYDSLVDLSLKLINKKDAPLNLFLKNDQFNLSNLQNNLKKNFFKFQINQLIMLIFDNYFLILKELHSLYLKSNNNNDNQIESITNQKLKIIRQNIRLMLDWSVNNFELGKFNFNASIGNCDIVYEHKILVVAKIFGRFLFQCRLFLSKIFNGQVKDTNLKTQSNNIQATPRNNFGLKEKKIIMGRIIEFLQSEILDFLLDIANSPEVPFESLNIFENLDTELDISQFNLNGIENITQKNTKIFTRALIPFKPINLKFLVLLINHLSQFNLFSIDLYSKKLISSGMIYDIESPQKMRNSNLVHYLILKNLKFARTSKIHIIFKNLKSKIFNDIKQNNPVNSKSIIDQLLEQPDIDNDFSNCITKAESIIDNSIIKYVFEDGLKIPTSDLEYLSKLDIDKKISLAEYLMKSLGNFMLGENYELINKSIKISSNELINQEYGSMSFYQGGEFYVKTWNITSEKICVLFSIFEGFYSLENFFSLIKEIFLIYNFQDDTFSNQNFNYLASPNSIQLSRPLMNEYENIKISSQVIIKLDSEQFYVILKILDNYKSVINYYSDNSISSKLANVPKVKNPTLNFVDLFRFFIDGYYNYTFNSQNYAPDYNFLYLLKRFSKKLSDFVEEFSSISEMLSPKELKEVLKNRNEDNKSYYLSDENHFGLVSELLKKLDELISYEINMSRQPVKSLIDSFTLNDNVNNFGIDTRTLFSDNFNNFDYNIRNIFMMVFNSPESIIISKTDTESWKNFNSNSKNFKDLTNLLKLVKKLKAEFFYNSISNFINSLISNSLLSESDKEKEKYIKYLNILLCFVLNNFISLKELIRLMFKLYLKKTNEKFAFDNQTCRIKETSFSFILDLVFNDYEDYVMLIQNRHQLNYSRNELFKVDPFLNINLGLIFLKKLPENNFGYHTNGFHNNKFCLVIENIKNGEMKNHKSKILKLLLESLTFNTFETINYLIRNTIIDTKIIISLFIQVLFYPYRLFGIFDFYSLKNHEDTETDYLTIDSKNVLIIIFILDEFNIVICQAIICLLLSQEENNNRKIIKEIIYKVLIGCVLNNIVENKVKLKVLENIFNYLNDILKKEILNVFYEIFLTSSTPFQMRLNFNEYSNYNNNDNDSQSPEILNKYRIKKFNNLAPYISYFLNSGLTIFSNEKNIEEKYNETLDCDNLTYLKKSKEDFYYLNDENTINLINNGFQNMIISYQKSKDKITKNEVLVGYTIFLKIIELNKNLFILNLVSTNDKIKNKYRKIIIAFQKILKIDLFKTYSKINELINDIICQIKTGVENYAKEKNIEVDGDTKSLLNTGKRQNQTRNDINNVKDEKEVSNDNNVCESGYNSELEDHSTVSSRFLEASKLTNGIDNTKFLNESLIYHNKVYFENCIKNDFSEIEQYFSSKELEVNEIHDKEWFLFDKINKKYLNLSIKPFDLLEEANKDATLNDGAINLQLFDATIEKENPL
Length2226
PositionKinase
OrganismAscoidea rubescens DSM 1968
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Ascoideaceae> Ascoidea.
Aromaticity0.12
Grand average of hydropathy-0.369
Instability index33.53
Isoelectric point7.98
Molecular weight260742.02
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09558
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            12|    1681.21|     189|     190|     618|     806|       1
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  144-  325 (138.14/30.32)	...............WHHTpiedsitsshldKG.F.....VEP............SPIrnelasaasLV.IHLKNLN.D.L..S.NNL..LQL..........KI.VRD........................................................................NYY.DKII......D..N..................SS.....FQ.P......P...SRVTLTD.......SKR..EAWLRDL.........ASINiPLKNLAEKKIPYGIKNRVL...IDQIILKR......VPISR..AIW......LIKCVG..........L.NE....LK....I......IKRKQNLP.....IN.S..YQLwINE...WTSH...LTFYLDNilS.QysnafF....NS
  334-  494 (143.66/31.79)	D........QSNTTTFNNN............NS.N.....YNN............NST.........ID.EKL.......L..DYLSL..NLIS.....SLKYKI.SYI..I.........N...L.............I..............FN..................L......FYE.KLIN......R..N................ifFNwlinsFK.KVekE.FE...LILLLQL.......IKIFSKFLIPN...........IIN.NNTNNTNNTNNTNNTNNTN...N....TNN......TNNTN..N........INTSTS..DL......SpENTDILLSS.........................LF..QIL.IFK...YDFI...LN......................
  496-  613 (98.70/19.80)	..........LSLKNLSTN............QN.F......................................NPNT.S.VqqNYSNI..NT........PN....NNN..N.........N...N.............N..............TN............T.....N......NNK.FYFS......N..NsiysqvnspttfgnspinFN.....YS.S...N.LD...S................FSKII........................DDASK............................VN..KEL......NLKKLS....................................MLYDikNLINF......................LFLKK..S.D.....W....LI
  618-  806 (312.84/76.92)	D........QLSLKTWNDT............KN.F.....LIK............YDI.........LD.IQLKPKN.K.L..DYKNI..QSLI.....NPDSKI.NSD..F.........N...I.............T..............FN............D.....V......NYY.YYLK......K..N..................FN.....FQ.SL..N.FD...EILILLK.......KERFNEICFKND.........CLLK.PLKQNKDDDSDTDTQTNTL...DFDLILNR......RNLTN..NEL......LLQKLN..DF......L.NKRDFFLQS...F......ICHDQEIYD..SLVDLS..LKL.INK...KDAP...LNLFLKN..D.Q.....F....NL
  811-  999 (145.43/32.26)	N........N..LK.................KN.F.....F.K............FQI.........NQlIMLIFDN.YfL..ILKEL..HSLYlksnnNNDNQI.ESI..T.........N...Q.............K..............LKiirqnirlmldwS.....V......N.N.FELG......K.....................FN.....FNaSI.gN.CDivyEHKILVV.......AKIFGRFLFQCR.........LFLS.KIFNGQVKDTNLKTQSNNI...Q.ATPRNN......FGLKE..KKI......IMGRII..EF..............LQS...............EILD..FLLDIA.......NS...PEVPfesLNIFENL..DtE.....L....DI
 1000- 1092 (91.99/18.01)	S........QFNLNG........................................................................I..E..............................N...I.............T................................................Q......K..N..................TK.....I........FT...RALIP................................FK.PI...................................NLKF..LVL......LINHLS..QF.....nL.FSIDLYSKK...L......ISSGM.IYD....IESP..QKM.RNS...NLVH...Y.LILKN..L.K.....FartsKI
 1093- 1275 (116.63/24.58)	H....iifkNLKSKIFND......................................................IKQNN.P.V..NSKSIidQLLE.....QPD..I.DND..F.........S.ncI.............TkaesiidnsiikyvFE............DglkipT......SDL.EYLS......K................................L..D.ID.........K.......KISLAE...............YLMK.SLGNFMLGE.............NYELINKS......IKISS..NEL......INQEYGsmSF......Y.QGGEFYVKT...WnitsekICVLFSIFE..GFYSLEnfFSL.I.....KEIF...LIYNFQD..D.T.....F.snqNF
 1276- 1471 (125.32/26.90)	NylaspnsiQLSRPLMNEY............EN.I.....KISsqviikldseqfYVI.........LK.I.........L..D..NY..KSVI.....N....Y.YSD..N.........S...IssklanvpkvknpT..............LN............F.....V......DLFrFFID......GyyN..................YT.....FN.SQ..N.YApdyNFLYLLK.........RFS...................K.KLSDFVEEFSSISEMLSPK...ELKEVLKN......RNEDN..KSY......YLSDEN..HFglvselL.KKLDELISY...E......INMSRQPVK..SLID.S..FTL.......NDN....VNNF....................
 1474- 1570 (70.33/12.23)	...................................................................................DTRTLfsDNFN.....NFDYNI.RNI..F.........M...M.............V..............FN............S.....P......ESI.IISKtdteswK..N..................FN.....SN.SK..N.FK...DL.......................T.........NLLK.....................................................LVKKL..............KAEFFYNSisnF......I.......N..SLI..S..NSL.LSE...SD..........KE..K.E.....K....YI
 1571- 1759 (147.70/32.87)	K........YLNILLCFVL............NN.FislkeLIR............L.M.........FK.LYLKKTNeK.F..AFDN...QT..........CRIkETS..F.....sfilD...L.............V..............FN............D.....Y......EDY.VMLI......Q......................N.....RH.QL..N.YS...R.................NEL.FKVDpflninlglIFLK.KLPEN.....NFGYHTNGFhnnKFCLVI........ENIKN..GEMknhkskILKLLL..ES......L.TFNTFETIN...Y......LIRN.TIID..TKIIIS..L.F.IQV...LFYP...YRLFGIF..D.F.....Y....SL
 1768- 1955 (133.60/29.11)	D........YLTI....DS............KN.V.....LII............IFI.........LD.....EFN.I.V..ICQAI..ICLLlsqeeNNNRKI.IKEiiYkvligcvlnN...I.............V..............EN............K.....VklkvleNIF.NYLN......D..I..................LK.....KE.IL..NvFY...EIFLTSS....tpfQMRLNFNEYSN.................YNNNDNDSQSPE............ILNKyrikkfNNLAPyiSYF......LNSGLT..IF......S.NEKNI..................EEKYN..ETLDCD...NL.TYL...KKSK...EDFYYLN..D.E..........NT
 1975- 2163 (156.87/35.31)	D........KI.......T............KNeV.....LVG............YTI.........F..LKIIELN.K.N..LF..I..LNLV.....STNDKI.KNK..Y.........RkiiI.............A..............FQ............K.....I......LKI.DLFK......T..Y..................SK.....IN.EL....IN...DIICQIKtgvenyaKEKNIEVDGDTK.........SLLN.TGKRQNQTRNDIN...NVK...DEKEVSND......NNVCE..SG.......YNSELE..DH......S.TVSSRFLEA...S......KLTNGIDNT..KFLNES..LIY.HNKvyfENCI...KNDFSEI..E.Q....yF....SS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.72|      23|      25|      69|      93|       2
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   69-   93 (35.39/26.32)	LSLLltNPFEDY..SNNIKRFSQAHLQ
   96-  120 (34.33/19.04)	LSDV..NAYDTFlsSSSSPVSSPAFLN
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.26|      16|      16|      21|      36|       3
---------------------------------------------------------------------------
    3-   21 (20.83/ 9.04)	SSQNNSRLhrkVQNYRQTR
   22-   37 (24.43/11.92)	SSNAASAL...VSRRNAIR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09558 with Med12 domain of Kingdom Fungi
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