Description | Mediator of RNA polymerase II transcription subunit 11 (Fragment) |
Sequence | TTMSNQSRNEFLQERLDSLAKIDQNLVSVIDNLSSLLNHIHIGKKNLLINNNNPNSNRQTEDDVNSDIKCFFQNLEESTTKLRREIKLHDNRIGYNFKKDNIVSILPINLTKNATWVGDWNFKNQINTVDMLFKNDPNYEQIDDNNNDIKKEDNNDDSNSNENKIEIKIENENLKKEE |
Length | 178 |
Position | Head |
Organism | Ascoidea rubescens DSM 1968 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Ascoideaceae> Ascoidea. |
Aromaticity | 0.06 |
Grand average of hydropathy | -1.075 |
Instability index | 41.68 |
Isoelectric point | 4.99 |
Molecular weight | 20820.70 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP09555 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 140.82| 43| 80| 52| 100| 2 --------------------------------------------------------------------------- 52- 100 (66.00/36.86) NNPnsNRQTEDDVNSDIKCFFQNLEESTTKLRREIKLHDNrigyNFKKD 135- 177 (74.81/30.28) NDP..NYEQIDDNNNDIKKEDNNDDSNSNENKIEIKIENE....NLKKE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) GKKNL 2) NENKIEIKIENENLKKEE 3) NYEQIDDNN 4) VDMLFKND | 43 161 138 129 | 47 178 146 136 |
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