<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09550

Description Med5-domain-containing protein
SequenceMNAIEIKPHHQPQHLSLKTLFNISIQKNISSINFIHLFDQYIAKFAENNPGDTSDASFFDLLNSVSDLEYILNISLINDIDNRNYGFINLLKVLYKKSYHIQINVISKFTNNDYYITLLFSQLINSSAVDAVLKSTLAADELLGNEISIKNEADDKDNVFNFFNFNVQKIRNNISKIVLNNPNYKIDLAKIKNFFESIFSYLSNVISFLNTNNNSINSNQINNLNMQLKLLRSFLYFLIELFLHINNYNTLILSMDKSNLNNYFIIPQKFNDFLFQLLLKLSSIKSLIYLLNYLKPQLNNYLSDLNQNTNSISLVSSIPKKSFNSDIVNNINKDKILKLIYLNSSLKNYLTSESLFSKGFLSLFNASYSSYSSNNLTNSIKRVIKSSFESFALSILNKSSRYLLKYWKLFIVKNIPLIIYQLKKDYSFSLSNFSAENTNQNSLTSTIVQKAIISVFLNDLDSKTIKIIKLFINEENDIKSKPFLSKFDFNSVSGNQTEKNTKKLNHFFSNSTNYFKFINDDDEEEDIFSSFPSTLTDIRHDFLKNCIALKLIAKEDFHTILKKDSLAESRILKEDDNIYLSDVFPDLVNVPKVFLEAFQLDQQQTLSFQSQLHRPTLNNFQIFSSSEPINNINFFLKTLFFMEANAFVDASDDSNENTLLKSNFVKFLSNFNNFEVLKQYEISLAIYQLMMELIEKKNDRLLNRLFLLLIILNEYKILNSMLQVPFPSDNLNSLNSNYGRVYFDNKPLDIILYFVSPLKFLLPIVHYCDSWHEIKEEENQVNHGVDVEMNSEDDNYQEDYCNFSVFILFIVYLTKKLNISQNELMTSYTFANTDYNYSKEGSNSHSKSFVLDYLSNLNTLNSNQPCFITNEGEAANMALLNDWIFALFGSSDGISDELISKSSIKTCFKLTPIIFKESFFANLSSLIDFDTLKEGTQYFFQSFLIGTLLGAFKWVEDFFFNFNFQDSSNDAIFIDQNFFISPEIKSILIKSIDILYILLLENHLGSNLNSQNWIIHKILLLLSSPTLSKSLEKIFYIFGKLRTLNNIEISIFNKIKNLINLFNKINYNTENNLLNINIISSKNKFFVQESFNSLHFDLKLMLNNYQEYQAYFNPNFRQNEQLLSLINNYKSRNPLDIYSPMALFTNQFESLMYWCNLENDNSRGINKKKVFVTPSFDVLLLDLVVAFSGCANIVYYFLSQIQKYYVEYLEIKRLYDESQLILQELKNENSDYGRKSKPNLVIQERKLTENVSKLGLKSENVSRQKENCIDVAVMLIICFSMNKLGSKNIKKQWLDLLLDNKSAYEMENKSHNTCLTIFSKVPEEYITLIENPDDIYTKNNRMKGSSDDKENKDDNNKRHKFKFDSNPDKDFSYSLLIINSKYHEHKKDVLIGEKQIKKIRKNENSIITADVSLLSEEIFGAFIQKLIQAVKDFPAVEESPNSIQ
Length1444
PositionTail
OrganismAscoidea rubescens DSM 1968
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Ascoideaceae> Ascoidea.
Aromaticity0.13
Grand average of hydropathy-0.215
Instability index30.83
Isoelectric point6.01
Molecular weight167806.35
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09550
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     341.15|      64|      98|      49|     113|       1
---------------------------------------------------------------------------
   17-   56 (33.35/ 7.04)	...........LK...TLFN.I......SIQKNISSI.N....................FIHLF.............................D.qyiakfaenN.......PGDTSD.A
   57-  131 (89.00/33.42)	SFFDLLNSVSDLE...YILN.I......SLINDIDNR.N..................YGFINLLKVLYKKSYHIQ..INVI......SKFtNNDyyitllfsqlI.......NSSAVD.A
  132-  189 (59.20/18.09)	VLKSTL..AAD.E...LLGNeI......SIKNEADDK.D..................NVF.NFFNFNVQK...IR...NNI......SK...........ivlnN.......PNYKIDlA
  190-  272 (48.21/13.39)	KIKNFFESI..FS...YLSNvI......SFLNTNNNSiNsnqinnlnmqlkllrsflYFLIELF..LHINNYNTL..ILSM......DK..............sNlnnyfiiPQKFND..
  273-  334 (60.86/18.80)	FLFQLLLKLSSIKsliYLLN.YlkpqlnNYLSDL.NQ.N..................TNSISLVSSIPKKSF...................NSD..........I.......VNNINK.D
 1033- 1085 (50.52/14.21)	KIFYIFGKLRTLN...NI.E.I......SIFNKIKNL.......................INLFNKIN...YNTEnnLLNIniisskNKF..............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.81|      15|      19|    1330|    1347|       2
---------------------------------------------------------------------------
 1330- 1347 (23.75/19.90)	ENPDDiytKNNRMKGSSD
 1350- 1364 (29.06/15.34)	ENKDD...NNKRHKFKFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.44|      18|      19|    1219|    1236|       3
---------------------------------------------------------------------------
 1219- 1236 (32.30/26.03)	QLILQELK.NEN.SDYGRKS
 1239- 1258 (22.14/14.76)	NLVIQERKlTENvSKLGLKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     821.03|     186|     308|     501|     692|       4
---------------------------------------------------------------------------
  356-  507 (179.42/83.37)	FSK..GFLSLFNAS.......YSSYSSnNLT........NSI..KRVIKSSF......ESFALS.ILNKSSRYLL....K..YWK...........LFIVKNIPLIIYQLKKDYSFS.........LSNF....SAENTNQnsltstivqkaiISVFLndldsKTI..........KIIK..LFINEEND..IKSKPF.......LS....KF..DFN..........SVSGNQ..TEknTKKLNHF
  508-  697 (283.77/147.70)	FSNSTNYFKFINDD.DEEEDIFSSFPS.TLTdirHDFLKNCIALKLIAKEDFHTILKKDSLAESRILKEDDNIYL....SDVFPD...........LVNVPKVFLEAFQLDQQQTLSFQSQLHRPTLNNFQifsSSEPINN............INFFL.....KTL..........FFMEANAFVDASDD..SNENTL.......LKSNFVKFLSNFNNFEVLKQYEISLAIYQLMMEliEKK....
  698-  820 (140.77/63.01)	..................................NDRLLNRLFLLLII............LNEYKILNS...........................MLQVP......FPSDNLN..SLNSNYGRVYFDN.......KPLDI............ILYFV.....SPL.........kFLLPIVHYCDSWHEikEEENQVnhgvdveMNSEDDNYQEDYCNFSVF....ILFIVY......lTKKLNIS
  821- 1004 (217.06/102.60)	QNELMTSYTFANTDyNYSKEGSNSHSK.SFV...LDYLSN...LNTLNSNQPCFITNEGEAANMALL..NDWIFAlfgsSDGISDeliskssiktcFKLTPIIFKESFFANLSSLIDFDT.LKEGTQYFFQ.......................SFLI.....GTLlgafkwvedfFF....NF.NFQDS..SNDAIF.......IDQNF..FISPEIKSILIKSIDI...LYILLLE......NHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.02|      22|      23|    1088|    1109|       5
---------------------------------------------------------------------------
 1088- 1109 (39.18/20.56)	QESFNSLHFDLKLMLNNYQEYQ
 1119- 1133 (25.32/10.50)	NEQLLSL.......INNYKSRN
 1145- 1161 (26.53/11.38)	TNQFESLMYWCNLENDN.....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09550 with Med5 domain of Kingdom Fungi
Unable to open file!