<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09512

Description Serine/threonine-protein kinase RIO3
SequenceMATPRAETEDQLKLRFQVELEFVQCLANPNYLNFLAQRDYFKVPEIINYLKYLQYWKEPEYARYLKYPMCLYFLDLLQYPEFRKELANAKCAKFIEDQQLLHWQHYIRKRSKLIPPNSNQGSSSNTGSSNVAISDSGNNSTSNTVSTASTNNAMQLNIGIPVGSGTTVEGPIETPVLSSVTNLPPVVPPSSPPVVSAGKCPWGKVKSPAAVDQTPPVSLRDIMSEQLASNLQIEEEENLVKEILVAEGIEKPAADGFDLTALQSMSSPSDDTSSDFLIAQMLQMQYNKEHDHGLKKVEEKFNGGSKVSVSLANYMMNPCSDDDDDSSDEDTDSGNRKKAWDKFEAHEKAFPAIPRCGYVKIDNEMVTKHDVTMSGRRNACKVMENFPPCIHTGDGASFDMQLSNKVYNTLKVYSKSEDDRRTRLHEKKEKSTSEMAMDAKTRLMLYKLVNNQILENVYGVISTGKEAVVLYANGGSPPPDTEMLVDIPKECAVKVFKTTLNEFKTRDKYIKDDYRFKDRFSKQNPRKVIHLWAEKEMHNLNRISKAGIPCPKVVLLKKHILILSFIGNDMKPAPMLKEVRFGKDEDDPVLNSAYNQTIDIITRLYKECNLIHGDLSEYNILWHEGKCYVIDVSQAVEPSHPHGLEFLYRDCTNIINFFSKKGVKNIHTPESLFTSLCGFDLNGSGPEAINQIQDYERDHELLTFAKPEKPFAFDFCWEQSKGASSPP
Length727
PositionMiddle
OrganismOrchesella cincta (Springtail)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Collembola> Entomobryomorpha> Entomobryoidea> Orchesellidae> Orchesellinae> Orchesella.
Aromaticity0.09
Grand average of hydropathy-0.534
Instability index43.22
Isoelectric point5.81
Molecular weight82170.34
Publications
PubMed=27289101

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
metal ion binding	GO:0046872	IEA:UniProtKB-KW
protein serine kinase activity	GO:0106310	IEA:UniProtKB-EC
protein threonine kinase activity	GO:0106311	IEA:UniProtKB-EC
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09512
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.63|      22|      86|       9|      30|       1
---------------------------------------------------------------------------
    9-   30 (39.17/25.32)	EDQLKLRFQVELEFVQCLANPN
   96-  117 (40.45/26.36)	EDQQLLHWQHYIRKRSKLIPPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.40|      65|      88|     296|     364|       2
---------------------------------------------------------------------------
  296-  364 (106.77/87.09)	KVEEKF.....NG.GSKVSVSLANYMMNPCSdddDDSSDEDtDSGNRKKAWDKFEAHEKAFPAIPRCGYVKIDNE
  381-  451 (98.63/67.58)	KVMENFppcihTGdGASFDMQLSNKVYNTLK...VYSKSED.DRRTRLHEKKEKSTSEMAMDAKTRLMLYKLVNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.09|      16|      20|     175|     194|       5
---------------------------------------------------------------------------
  179-  194 (30.53/21.45)	SVTNLP......PVVPPSSPPV
  196-  217 (24.56/ 7.30)	SAGKCPwgkvksPAAVDQTPPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      92.29|      19|     421|     240|     259|       6
---------------------------------------------------------------------------
  240-  259 (27.95/23.58)	VKEILVAEGIEKPAAdGFDL
  663-  681 (32.81/22.15)	VKNIHTPESLFTSLC.GFDL
  698-  715 (31.53/20.99)	DHELLTFAKPEKPFA..FDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.68|      19|     535|      67|      91|       8
---------------------------------------------------------------------------
   44-   65 (31.35/18.34)	PEIINYLKYLQYwkePEYARYL
   68-   86 (37.33/29.79)	PMCLYFLDLLQY...PEFRKEL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09512 with Med31 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EGPIETPVLSSVTNLPPVVPPSSPPVVSAGKCPWGKVKSPAAVDQTPPVSLRDIMSEQLASNL
2) IPPNSNQGSSSNTGSSNVAISDSGNNSTSNTVSTAST
169
114
231
150










Molecular Recognition Features






MoRF SequenceStartStop




NANANA