<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09509

Description Mediator of RNA polymerase II transcription subunit 24 (Fragment)
SequenceSVRYKQTLYSSASLFEIDASYVSVTLNLFVVVLIRTLLKFNLSIDKMVLGIGDVQRTSQEAQAKSLIMKAWRERWTEVQWGINIRKLVDDSADGSFLADCILQQALSGPGPNSLVLSYLMHSIHSQIVTTASVLLSVSKYDAFHKLHCVASLLDLLSSIKDRIILNDNQGKDDCIQLALALQSVVCWLLSCMYSSLENLSDITEFPAEAEDSKIVLKCRNLMDYFLVDPYLFNLINVANKEDEESYVKIIKMSKEVDKFVDGHNQREISHVTSLIDKLSKPRVPKTTKTHPLEKSFDGLQTKVGNPSIQAIIMKAALLRSSQDIPAIVSELILVKQLQNVDLVNFYSEILHSALMGLVDAFGKEQELAFIGFTFLQLPSLVNTVREKLLDSTNDAFLRGLEVYIMNESCLNVADAKLHCCTLEFLLKSFANVRLINETDKASLLKLRTSKGSSIKPTPGSSPKTFNVIITAAATTGRLQQFTSKLIKLNQLSRQASGELNKASNTRAIIFDLSFLMLCYIVQLHGPKALSSEEPDSFFEEWYKDCMVENHVAKNPDVIINRCDSNKVDLLLNQYIQGDTELKTSLVFWHEICANSVGVTKEVLTAWESDGTTFNEVKRILDVFRSKICSIPVCISAWLCAYIQVNPEEKSTKAKEILNYFLTSSTVMSFDNQDHFKERNALMSQIISRMMNCIQSSDKSPVNSPTYNFESKPVAELYKSCWACMNKRGLIDVETTVNLQHLLQMSGPHYFVQNMVEEMLRLQHSQELAQRCDLLYGVLHYDLKSCTAALVRVVVPTVLHFWTSDSSFMEPQIKALVSLSVDCILSYYYHASSLKIKEERKDESDSEPQSKRRKLFEATSLQKENLVDLQIMLKDLYGEFYKVLHNVYESTPAIVFILQFLEELSMKTPTTTLLTSLPHQVVTQLMSLMCDEMDPDLLLGLFCLTNKNSRLNCAQALCRLKHLRHINEYHEPRSHSPAPGS
Length980
PositionTail
OrganismOrchesella cincta (Springtail)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Collembola> Entomobryomorpha> Entomobryoidea> Orchesellidae> Orchesellinae> Orchesella.
Aromaticity0.08
Grand average of hydropathy-0.048
Instability index45.56
Isoelectric point6.18
Molecular weight110782.72
Publications
PubMed=27289101

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09509
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     263.72|     104|     169|     623|     791|       1
---------------------------------------------------------------------------
   80-  226 (145.15/81.59)	WG.INIRKLVDDSADGSfladciLQQALSGPGPNSLV...LSYLMHSIHSQ.IVTTASVLLSVSKYDafhkLH.CVASLLDllssikdriilndnqgkddciqlalaLQSVVCWLLSCMYSSLENLSDITefPAEAEDskivlKCRNLMDYFL
  623-  661 (39.62/44.84)	...........................................................................................................FRSKICSIPVCISAWLCAYIQVN..PEEKST.....KAKEILNYFL
  721-  791 (78.95/124.30)	WAcMNKRGLIDVETTVN......LQHLLQMSGPHYFVqnmVEEMLRLQHSQeLAQRCDLLYGVLHYD....LKsCTAALVR........................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.22|      30|     172|     512|     545|       2
---------------------------------------------------------------------------
  512-  545 (49.37/45.37)	LSFLMLCyiVQLHGPKALSSeePDSFFE.....EWYKDC
  686-  720 (51.84/33.76)	ISRMMNC..IQSSDKSPVNS..PTYNFEskpvaELYKSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.59|      17|      26|     239|     263|       3
---------------------------------------------------------------------------
  227-  248 (17.67/ 8.93)	VDPYlfnlINVANKEdEESYVK
  256-  272 (29.92/33.64)	VDKF....VDGHNQR.EISHVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.83|      21|      26|     368|     392|       4
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  368-  388 (35.51/27.19)	AFI.GFT.FLQLPSLVNTVREKL
  395-  417 (27.32/10.54)	AFLrGLEvYIMNESCLNVADAKL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.67|      28|     532|      52|      79|       5
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   52-   79 (51.46/35.07)	GDVQ.RTS....QEAQAKSL.....IMKAWRERWT...EVQ
  577-  617 (29.21/16.90)	GDTElKTSlvfwHEICANSVgvtkeVLTAWESDGTtfnEVK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09509 with Med24 domain of Kingdom Metazoa
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