<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09478

Description Uncharacterized protein
SequenceMDITMDMLDYDMNDGGLPSSDMQDNYAEAIMLDDAVPNNDAVELANPHNSYPGATVTARPVLEIIENEIANQVAKRGASHNDTLPIGRVVIKTEQNDVELQDNFGAATASDPVVPPKYAVVFLVESTGRLSRHMEKIKADYLTPILRHFRDANQAYSSDSPIAGWAKDAYYGFVAFRSTDATPGKEVNCSTKPTDNEEMALRNIEKLHAASTSLLCSHRVCLLEAFAAGLHCLDTVQSTYMTNAQHVEKHFILLCQSEPLEEPQSYSKNTTSFHLNSLADVPAVLLDARVHLSLIATRNIATLHKLVAACQDPLSAMETSAATDERHLVLLNGLSIRPPPPITVKTSPERVASPAALPPAPVVGSLLKNELIAAYVSSPLSIRTPLSQQSVLSVETITSPTPVDNKPNTLQPASEPYAKAESPAVVKTPQPEITIPSTPDNLANLVKNSESPRPQLTPGNPVPTQQGASPIPSYAAMKVNSPSVTVGSPLPQALPQPRLPIPIPVPNIALTPNISGAVPLMPPGPSPLMNTGRPPHVSVSDLYNVARTAGQDTLGRPLMGNPGMPNTSNALAALQQNAGMLISQLSNPSPVPVPTTLPRVVNERCVVWDGLVEWVNQESRMSRQMNQQPCEVWVPMNDIIKAERWPQKLTIQFLPRSFSQAIHPYMSDPVKVFFQFKPAPNGDQSAIKELHEHFMRRSAVATFGCILIPNNLSNPVNPLVITNMGKPNEAPLQLELRVIVFVFNVKAGQFQGWIPREQGGFVDALRHITQATANQQRQLSQNQLQPQQQAQQGMPGVIPALQQRTMPIPQQQQAFGSNPNMMEASQYGTMLQQQQSNQQQQQQQVMQMNTQQQQQQQQLVNLGGYGNMYGAGGNPQMNPQTLTQEQSMRLQQQQQQQQQQQQQQQLQQSHQQQQAQQQHMQRFLQQQVHQQQQQQQMHQQQGSAAQPQDPQLRQLLQNSSPRLPGGQL
Length968
PositionUnknown
OrganismRamazzottius varieornatus (Water bear) (Tardigrade)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Tardigrada> Eutardigrada> Parachela> Hypsibioidea> Ramazzottiidae> Ramazzottius.
Aromaticity0.05
Grand average of hydropathy-0.470
Instability index65.97
Isoelectric point6.13
Molecular weight106406.27
Publications
PubMed=27649274

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09478
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     281.32|      38|      38|     880|     917|       1
---------------------------------------------------------------------------
  773-  812 (47.67/13.64)	A.........NQQRQ....LSQNQLQPQQQAQQGmpgvipalQQ.RT......MPIPQQQ
  813-  852 (44.97/12.48)	QafgsnpnmmEASQY....GTMLQQQQSNQQQQ................QQQVMQMNTQQ
  853-  894 (61.63/19.64)	Q.........QQQQQlvnlGGYGNMYGAGGNPQM........NP.QTLTQEQSMRLQQQQ
  895-  928 (63.27/20.35)	Q.........QQQQQ....QQQQQLQQSHQQQQA........QQ.QHM..QRF..LQQQV
  929-  967 (63.78/20.57)	H.........QQQQQ....QQMHQQQGSAAQPQD........PQlRQLLQNSSPRLPGGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     249.66|      40|      50|     346|     385|       2
---------------------------------------------------------------------------
  283-  354 (30.01/10.02)	AVL.L.DAR.VHLSLIatRNiatlhKLVAA.C.....QDPLsametsaatderhlvllnglSIRPP............................................ppitvkTS.PERVASP
  355-  394 (61.38/28.86)	AAL.P.PAP.VVGSLL..KN.....ELIAAYV.....SSPL....................SIRTP..................................................LS.QQSVLSV
  395-  429 (46.94/20.19)	ETItS.PTP.VDNK....PN.....TLQPA.......SEPY....................A..KA..................................................ES.PAVVKTP
  433-  465 (40.89/16.55)	ITI.P.STPdNLANLV..KN.....S...........ESP.......................RPQ.................................................lTP.GNPVPTQ
  466-  497 (42.99/17.81)	QGA.S.PIP................SYAAMKV.....NSP.....................SVTVG..................................................SPlPQALPQP
  498-  594 (27.44/ 8.48)	R.L.PiPIP.VPNIAL..TP.....NISGAVPlmppgPSPL..................mnTGRPPhvsvsdlynvartagqdtlgrplmgnpgmpntsnalaalqqnagmlisqlSN.PSPVPVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.63|      22|      75|      21|      42|       3
---------------------------------------------------------------------------
   21-   42 (38.85/26.08)	DMQDNYAEAIMLDDAVPNNDAV
   99-  120 (38.73/25.97)	ELQDNFGAATASDPVVPPKYAV
  551-  566 (20.04/ 9.10)	..QDTLGRPLMGNPGMPN....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      74.17|      24|      44|     647|     670|       5
---------------------------------------------------------------------------
  635-  657 (17.70/ 6.76)	......P..MNDII...........kaerwpQKLTIQFLPRS
  658-  698 (35.14/21.35)	FSQAIHP.YMSDPVkvffqfkpapngdqsaiKELHEHFMRRS
  703-  721 (21.33/ 9.80)	FGCILIPnNLSNPV.................NPLVI......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.32|      19|     587|     164|     182|       8
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  164-  182 (37.79/28.14)	GWAKDAYYGFV.AFRS.TDAT
  752-  772 (29.53/20.35)	GWIPREQGGFVdALRHiTQAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.68|      12|      22|     597|     608|       9
---------------------------------------------------------------------------
  597-  608 (23.73/15.55)	LPRVVNER.CVVW
  621-  633 (20.94/12.80)	MSRQMNQQpCEVW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09478 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNISGAVPLMPPGPSPLMNTGRPPHVSVSDLYNVA
2) QQQLVNLGGYGNMYGAGGNPQMNPQTLTQEQSMRLQQQQQQQQQQQQQQQLQQSHQQQQAQQQHMQRFLQQQVHQQQQQQQMHQQQGSAAQPQDPQLRQLLQNSSPRLPGGQL
3) TANQQRQLSQNQLQPQQQAQQGMPGVIPALQQRTMPIPQQQQAFGSNPNMMEASQYGTMLQQ
4) VLSVETITSPTPVDNKPNTLQPASEPYAKAESPAVVKTPQPEITIPSTPDNLANLVKNSESPRPQLTPGNPVPTQQGASPIPSYAAMKVNSPSVTVGSPLPQALPQPRLPIPIPVP
512
856
772
391
546
968
833
506










Molecular Recognition Features






MoRF SequenceStartStop




1) DPQLRQLLQN
949
958