Description | Mediator of RNA polymerase II transcription subunit 21 |
Sequence | MDRLTQLQDAIDAMARMFTNSIYYVHEKSGMAELNPEIPVTQPKVQADEPQIFQDNVRELVSDLVKKAKEIDALIELLPGIQQTEEQQMELLKSLEDENQQANREYQEAVKEMEQVKEQINRSLRAIADDTQQSSLK |
Length | 137 |
Position | Middle |
Organism | Choanephora cucurbitarum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Mucoromycotina> Mucoromycetes> Mucorales> Mucorineae> Choanephoraceae> Choanephoroideae> Choanephora. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.743 |
Instability index | 46.92 |
Isoelectric point | 4.48 |
Molecular weight | 15804.60 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP09452 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 50.71| 15| 15| 90| 104| 1 --------------------------------------------------------------------------- 84- 101 (17.74/ 9.27) TEEqqmEL.LKSLEDENQQ 102- 119 (17.14/ 8.74) ANReyqEA.VKEMEQVKEQ 120- 133 (15.83/ 7.58) INR.....sLRAIADDTQQ --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) LIELLPGI 2) QTEEQQMELLKSLEDENQQANREYQEAVKEMEQVKEQINRSL 3) VQADEPQIFQDNVRELVSDLVKKAKEID | 74 83 45 | 81 124 72 |
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