<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09442

Description "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial"
SequenceMGFTALARWNNAPTTAIELINQNIIRNHQGQYRGRWQSTVRSYRSTMGSVPGFQVHAERSMCTLSMDENVFVLLEDTAAPARAEYLQQIGDPAQSQLPGPTHYRHTFLTLSPPGSLEQLLAQLRARWVSVRQASQPTSSQKGTGQQLVIDGHIYAIGNDWLVRAGNVILAGGAVKGMLLEAEYLPLPTMPTAGDGTPELLSNLLISVLPNVADPKIVAVAVSDSIWEEALWDTEDEEVSNEEKTKMLEQEDDIYVSEEDSPASRKGDWVYGARGISTAVHFYQNRQLEQYASKEAQRLTLRQLVFFGRSMNEDRLIKSANYVRTELPVRIAHRLRDLQALPYVVVTQEGVAKVYELYWSAFDKFRRYPQIKNLAENEAFCTFLRGLLDEHKTVIPNLSLGLSLSSPYLAPDRLDSFMRRMLVSRISRRVLAEHHIALSKAMTSKLCPTDRVGIICTGLKVKDSIEKCARFLRKRRHDVDQDPENGIPSDAEWSEVIVDGHVDTRFAYIREHLEYIIFELLKNSFRATRFRHPDTSVLPPIRATVVAGENDVCIRISDQGGGLLTPEIKSPSDLFSFSHVRNATRLADARLGALRSVSVRGMTATVDEQVTAWQRATNAENPQHGAGIGSHPRIGIGLPMSNIFATYFGGSLELVSLDGYGTDVYLRLPKLGTNLEGIEL
Length679
PositionHead
OrganismGrifola frondosa (Maitake) (Polyporus frondosus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Polyporales> Grifolaceae> Grifola.
Aromaticity0.08
Grand average of hydropathy-0.273
Instability index46.41
Isoelectric point6.31
Molecular weight75855.26
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
mitochondrial matrix	GO:0005759	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09442
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     160.17|      57|     480|     122|     195|       5
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  122-  194 (71.98/68.37)	QLRArWVSVRQASQPtssQKGTGqqlvIDGHIyAIGNdwlvraGNVILAGGAVKGMLLE....aEYLPLPTMPTAGD
  608-  675 (88.20/50.80)	QVTA.WQRATNAENP...QHGAG....IGSHP.RIGIglpmsnIFATYFGGSLELVSLDgygtdVYLRLPKLGTNLE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09442 with Med20 domain of Kingdom Fungi
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