Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MDATKAPPVLSHRFTLELEFVLSLSNPQYLQYLALFHPHLLNNPATTRDVAEADDSDADRFARYLKYLYSYWRTPQYAQYLTHPGSTLRNLELLQQEQFRKDLIKPDVIARLFETNEVTSTSQDGTDEREASR |
Length | 133 |
Position | Middle |
Organism | Cladophialophora carrionii |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Chaetothyriomycetidae> Chaetothyriales> Herpotrichiellaceae> Cladophialophora. |
Aromaticity | 0.11 |
Grand average of hydropathy | -0.635 |
Instability index | 26.10 |
Isoelectric point | 5.29 |
Molecular weight | 15496.08 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP09428 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 119.90| 35| 45| 2| 38| 1 --------------------------------------------------------------------------- 2- 38 (58.99/41.74) DATKAPPVLSHRFTLELEFVLSL.SNPQYLQYLAlfHP 49- 84 (60.90/36.95) DVAEADDSDADRFARYLKYLYSYwRTPQYAQYLT..HP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EREASR 2) SDADRFARYLKYLYSYWRTPQYAQYLTHP | 128 56 | 133 84 |
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