<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09404

Description Uncharacterized protein
SequenceMPTHNRYPPGVNPYAPSTSSKTPRTHRPNLPSRPNLHAPKVLLDDADIEDFHPPEWRTVLNSRVDLGYPDFYPSRPGFDQPEDVLTEENVKNGFSGRNFIAVGAEVFSMHGPIHNHLTSGGLNLLQNLGKDLIEKRQEMMPKIGERSFRIPVRVTYNDTKRLQFLNDLANPNVPLYKLMRTPVPHGFKGIELLDSMFSPNIGPMGPGHSRTPSGSNNNAKILSDPIPLDRALWFIRVLGSNEISAHRSRTQPQPQHHQNTNATPNTPVGVSPAAPTPSSSTTITTTPTLQVSSNDWYTQEFTNTFISWLRVQFGQLSLPNNNPKTNVAKPGVPPPKSSAGVLGDEKLRSRWLSKWDYSAQLMRKLHRHQLLSSRLLSGWMADFLGYANLAQLGFLAQLIGEYLEDVTKHLCNARQCVRNACEKLKEIRASPASGSLIKVDSMLTSIVKSLCEANQETLLSPTTWKLHSELLTTILPDQRPSIRIRNEALWFRINVDERSSSPRRQQMAEMQKLDSICEDTNMLELTRSFFDGTSSPTDTAPDLSRLEDKVFILLNWAMGLFQLGSHRPYAVYTLLKHWHDQHEEHQAKQANPHVIDLFPILYEWLDTSAAARKDENVQAIGITVGEITRQGMFSYGRYLQTLIAKGQTARSQVAGQSPSHHLAMLKAMPIFAVAKDLVQQRRIALCGDNRESKIREDTEENILMDQFRDEVMEYVPEVFGKRIYKNSAVLRDVIDYQIPCSTKMTRYLYVQARFWLAPEAGRYLRGDQQTPPMDASTFSRVMQVFRTCRGHATMADFIIRALQDSEDEEVLDVIIDIVRRDADVWTAMDGWSRLGDKLLDRYHTLQTQGKNHLRTLELLEYLVKKGRLTSDEEDEVKLIQSELPKVGNHLPAKLDFKESLHGMQHMLSSGKEENAAVLAPKLFVRHGSFGNWSNQWWSTIIEHVQHPSSHVSYDATLRVVTSHIVSVCKDVQDQLETVISAWLENLAPAALVDMFGKRSGLLISHLLLDLVVKRCLSTSTLLERLIYPVWRYASSVILTPRRRLSGKQIQAVTNCINVAAQLLVSPPLVSTLPPSIPTHSLIVLAYRQAVFCGTSVQNLIRHLPLFVVLQKSAMLSENTNSLISSLLRCLAMTAEFKTAAFRNLSVLKDTFLSTEWSKPSSCHGLEAGMEDILKLIMSEKPPSDKSRVTTFDNTARLSAWRWTRIVLEMRSDFKGLGTRINNGEDVAETRQTLHRQVLATLDRAATADDTDLLCEAFRGMDSVVTQEILVAGLDRLSNLLSQAIGAETQNHLEEHVKSIQQILRILDSTFHQRSSDPINENTILSARHKLLDLLTVALQSIERQLSDNDLVIHHDISTPPQPGELLKMVLDLLKFTLGLLVIESNSPTTPKPNFPNLAVGFFKVMLSCHDVLDEESAQMMSDMLSYIIDSTPPQSRISCQTALLGETTSSNVQNILSSKPILASALPHLSPLKRNMALLASSTEDEGNGHNLDSVLTMEERRWELFEQINPIPKKPNHQDLYLVNKSSIKDTSSISMGLFNPKFTRDCLPNIANHWKIPSDNDQEQDEEHDQEDEEEEEEGNLPWENYASERTLGDGFNESLFERQRSTLLFNNSEELGLAQPNVGSDDDDLEVDIPLALSLSASKKRRISTRSQTSPTKSNTKPKGKGIGAGSNKDPISIEDNSSSDEDDSDAEEDAEVVEVKNQPSKRPRTTSTSTAGRRPSTSGKAPAKATATARKSVGGKSVARKSTGGKSTRGTGGKAPRGRRRSSQVE
Length1774
PositionKinase
OrganismKwoniella mangroviensis CBS 10435
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Kwoniella.
Aromaticity0.06
Grand average of hydropathy-0.438
Instability index49.06
Isoelectric point6.54
Molecular weight198564.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09404
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.99|      36|      39|    1300|    1338|       1
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 1300- 1338 (55.04/38.73)	QQILRIL...DSTFHQRSSDPINENTILSArhkLLDLL..TVAL
 1339- 1379 (52.95/29.46)	QSIERQLsdnDLVIHHDISTPPQPGELLKM...VLDLLkfTLGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.09|      23|      39|      28|      50|       2
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   28-   50 (41.17/28.95)	PNL.PSRPNLHAP........KVLLDDADIED
   69-   92 (38.93/26.84)	PDFyPSRPGFDQP........EDVLTEENVKN
 1392- 1415 (17.99/ 7.05)	PNF....PNLAVGffkvmlscHDVLDEE....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     127.44|      34|      39|     382|     415|       3
---------------------------------------------------------------------------
  352-  375 (25.02/14.17)	.........LSKWDYSAQL....MRKLHRHqLLSSRL
  382-  415 (58.57/45.43)	DFLG..YANLAQLGFLAQLIGEYLEDVTKH.LCNARQ
  422-  455 (43.85/31.71)	EKLKeiRASPAS.GSLIK.VDSMLTSIVKS.LCEANQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.58|      33|      38|     851|     883|       4
---------------------------------------------------------------------------
  851-  883 (52.40/41.62)	NHL.RTLELLEYLVK.KGRLTSDEEDEVKLIQSEL
  888-  922 (46.19/35.57)	NHLpAKLDFKESLHGmQHMLSSGKEENAAVLAPKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.27|      37|      43|    1063|    1099|       7
---------------------------------------------------------------------------
 1028- 1052 (29.47/15.91)	...........PVWRYASSVILTPRRR.LSGKQIQAV
 1063- 1099 (61.79/43.09)	LVSPPLVSTLPPSIPTHSLIVLAYRQAVFCGTSVQNL
 1109- 1144 (53.00/35.70)	LQKSAMLSENTNSLISSLLRCLAM.TAEFKTAAFRNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.29|      13|      30|    1239|    1256|       8
---------------------------------------------------------------------------
 1239- 1256 (17.14/18.12)	ATLDRAataddTDLLCEA
 1271- 1283 (22.15/10.46)	AGLDRL.....SNLLSQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.87|      23|      38|    1435|    1457|       9
---------------------------------------------------------------------------
 1435- 1457 (38.26/22.20)	SRISCQTALLGETT..SSNVQNILS
 1470- 1494 (34.61/19.39)	SPLKRNMALLASSTedEGNGHNLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.06|      18|     256|       8|      25|      11
---------------------------------------------------------------------------
    8-   25 (36.75/19.19)	PPGVNPYAPSTSSKTPRT
  267-  284 (34.31/17.41)	PVGVSPAAPTPSSSTTIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.78|      25|      31|     498|     524|      12
---------------------------------------------------------------------------
  462-  502 (30.77/17.83)	TTWKLhSEL..LTTILPDQrpsirirnealwfriNVDE..RS.....SSP
  503-  536 (31.01/25.02)	RRQQM.AEMqkLDSICEDT...............NMLEltRSffdgtSSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     202.05|      61|    1450|     206|     266|      14
---------------------------------------------------------------------------
  206-  266 (109.78/77.55)	PGHSRT.PSGSNNNAKILSDPIPLDRALWFIRVLGSNEISAHRSRTQPQPQHHQNTNAT......PNT
 1658- 1725 (92.28/63.74)	PTKSNTkPKGKGIGAGSNKDPISIEDNSSSDEDDSDAEEDAEVVEVKNQPSKRPRTTSTstagrrPST
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09404 with Med12 domain of Kingdom Fungi
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