<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09386

Description Uncharacterized protein
SequenceMPPHSRYPPGVNPYAPSTSSKTPISNSASSSRVVRPTLSGRSNVLAPKVLLDDVDIEDFHPPEWRTVLNSRVDLGYPDFYPSRPGFDQPEDVLTEENVKNGFSGRNFIAVGAEVFSMHGPVHSHLSSGGLNLLSNLGKELIEKRQEMMPKIAERAFRIPVRVTYNDTKRLQFLNDLSNPNVPLYKLMRNPVPHGFKGIELLDSITHSEPIPLERALWFIRVIGSNEVSAHRSRTQPTQPQAPNTPIAAAPKFTNTFISWLRIQLGQLALPISNKSVVKPGVPAPKASAGVLGDEQLRARWLKKWDYSTQLMRELHRCQLLSSRLLSGWMADFLGLSNLAQLGFVAQLIGEYIADMVKHLCNARHCVRNACAKLQEIRSSAASNTSGKVENMLITIVKSLCESNQEFLLSPTTWKSHSDLLSTILPGVESAVKRRNEALWFKIDVDERSSGPRRQQMAEIQRLDSICEDTNMVELTRSFFDGPSSATNTFPDMSRFEEKMFVLLNWAMGLFQLGSHRPYAVYTILKHWHDQHEEHQSKQPKSCVIDLFPLLYKWLDISAAAKKEENIQAIGITIGECTRQGMFSYGRYLQMLIAKGQTARNQASGRPPSHHLALLRAMPIFVIAKDLIQQRRIALCGDDAPLRIEQDAEEASLMEQFKEEVMEYIPEAFGLKHYRNSEALKNVIDHQIPCSSRMTRYLYVQARFWLAPAAGKRLKGDDLTPPMNASTFARVLQIFRTCRGHATIADFIIRAIQDSDDAQTLDVIIDTIHRDADVWTAMDGWSRLGDKLLDRYHVLQTRGKSHRRTLELLEYLVKKGRLSPDEEDEVKLIQEDLPKPPQTIPAKLDFKESAYSLQQVLSAAKEDNATALAPKLFVRHGSFNNWSHQWWRAIVEVLQHPSSHLSHDATLRTVISHIAVVMQETPDSLEPIIIAWLDTLAPVALIDTLGKRSGSLITHVLLELVIARQLRTLTLLERIVYPIWKHTSNIVLTPRRRLSSKQTQAVGNTINIVAQLLVSPPLIPFLPPFDPTNSLIALAYRQAVFCGFHVQNLIRHLPFLVVLEKSANLSDNSNKTISSTLRCLAMTAEFKTAAFRNLGILKDAFLSTEWSKPSSCHELEAGMEDTLKLIMSEKPPNVSTPASKSRLTTFDNTARLSAWKWTRIVLEMRSDFKGLANRVSNTENTPIDVVEARQILNKQILATLDRAVTADDTDLLCESFRGMDTVVTQEILVVGIDRLSNLLSQAIGSENQHHLEESIRSIEQILRILHSTYNTPQCIADAAILNARHRLLDLLTVALQSIDRGLSDTELEIHQDISPPQPGDLLRIVMTLLRFVLGLSVIDNGSPTAPKPNFPNLAIWFFKVMLTCHNILDLDSASMMSDMLAYIIDSTPPQSRLACQTALLGETNSTTVQHILALCPTLAKSLPHLSPIRRNMALLAPENETDTVNGIDSALHMEDRKWELFEQMNPLPKQPLHQDLYLVNKPIKDNSSISLSLFNPKITRDALPNVGTDWAIEKESGIGDSPESLAENEVEIGNPRSEVDSEMDRPWENWASEYDLSNGFNSSSYLKQKVTSLFNGKEEIDLDLDDSTVDQIKDESFISSSPRKRRMSTRSHNSPNKSITLLKGTTNKDPIAIDESSSSSSEDEEPLALTNLPSSNKKPRTSSNSTSKSQKNQTSTIASKAPRKSIGGKVPAKTTGRKPSTSGKSVRGGGISGKAPRGRRKSTQND
Length1725
PositionKinase
OrganismKwoniella pini CBS 10737
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Kwoniella.
Aromaticity0.06
Grand average of hydropathy-0.325
Instability index48.48
Isoelectric point7.96
Molecular weight192908.09
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09386
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     246.60|      80|     111|    1436|    1545|       1
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 1445- 1528 (130.86/98.11)	GIDSALHMEDRKWELFeqmNPLPKQPLHQDLYLVNKpIKDNSSISLSLFNPKI.TRD.ALPNVGTDW...AIEKES.GIGDSPESLAENE
 1558- 1643 (115.75/45.02)	GFNSSSYLKQKVTSLF...NGKEEIDLDLDDSTVDQ.IKDESFISSSPRKRRMsTRShNSPNKSITLlkgTTNKDPiAIDESSSSSSEDE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.12|      15|     196|     123|     137|       2
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  123-  137 (27.67/14.80)	SHLSSG......GLNLLSNLG
  322-  342 (20.45/ 9.10)	SRLLSGwmadflGLSNLAQLG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     285.85|      87|     111|     561|     654|       4
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  561-  604 (51.40/34.89)	..................................................................KKEENIQAIGITIGE...CTRQGMFSYGRYLQMLIAKGQTARNQASG
  605-  715 (115.11/119.57)	RPPSHHLALLRAMPIFVIAKDliqQRRIAlcgdDAPLRIEQDAEEASLMEqfkeevmeyipeafglKHYRNSEALKNVIDHqipCSSR.MTRY.LYVQARFWLAPAAGKRLKG
  719-  802 (119.33/100.55)	TPPMNASTFARVLQIFRTCRG...HATIA....DFIIRAIQDSDDAQTLD..........viidtiHRDADVWT...AMDG...WSRLGDKLLDRY.HVLQTRGKSHR.....
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     406.60|     151|     292|     822|     993|       5
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  803-  936 (148.34/147.17)	..........................RTLELLEYLV...............................kkgrlspdeEDEvklIQEDLpKPPQtiPAKLdFKESAYSLQQVLSAAKEDNATALAPKlfvrhGSFNNWSHQWWRAIV...EVLQHPSSHLSHDaTLRTVI......SHIA...VVMQETPDSLEPIIIAWLDTLA
  940-  993 (32.90/21.47)	LIDTLGKRSGSLITHVLLElviarQLRTLTLLERIVYPIWKHTSNI....VLTPRRRL.................................................................................................................................................
 1234- 1418 (225.37/159.12)	LSNLLSQAIGSENQHHLEE.....SIRSIEQILRILHSTYNTPQCIadaaILNARHRLldlltvalqsidrglsdtELE...IHQDI.SPPQ..PGDL.LRIVMTLLRFVLGLSVIDNGSPTAPK.....PNFPNLAIWFFKVMLtchNILDLDSASMMSD.MLAYIIdstppqSRLAcqtALLGETNSTTVQHILALCPTLA
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.39|      40|     220|     199|     240|       6
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  199-  240 (66.64/49.63)	ELLDSITHSEPIPLER...ALWFirVIGSNEVSAHRSRTQPTQPQ
  418-  460 (63.75/41.01)	DLLSTILPGVESAVKRrneALWF..KIDVDERSSGPRRQQMAEIQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.28|      22|      22|    1679|    1700|      11
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 1656- 1675 (31.55/19.86)	KKPR.TS..SNSTSKSQKNQTST
 1679- 1700 (39.42/26.97)	KAPR.KSIGGKVPAKTTGRKPST
 1703- 1722 (28.30/16.92)	KSVRgGGISGKAP...RGRRKST
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09386 with Med12 domain of Kingdom Fungi
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