<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09377

Description Cyclin C
SequenceMSSSFWSSSHCRYWLTTRPAILAARQTDLRYSTPKQLYCLYIFFAQLIQKLGKRLLLRQIPIATACVFFRRFYLKNSICETNPYLVLAACVFVAAKVEETPVHIKSVVSEAKVVFNEHNIKFFPAEPNRLGEMEFYLLEDLAFHLVIFHPYRALLHITGREPADSGKFPLSRVDEDLAIRRKEAEAKKKRDDEARRASHLPPRPGSVSVAQQSAAATVAAKDLGEDGTLGESEPERIRRLMGRGSGEGIMEIDEGVLQISWFILNDTYRTDVHLLYPPYVIALSAVYIAFCLTSMNNNSASRTRTSSSQLHTLANSMSTNEALSLPPPPASAAEFLAGFQVNLPILFACVQDIVCLYPVWETFEPTSMRHNPAAAAAHASPAHAQTHPNGQQQQQGKTSKDNTEKFGPEEAAALVRRMIEERMVDMGHPNNAGKSDKRSNPPTGSLGNTSHGVDPLTGRKRARR
Length464
PositionKinase
OrganismKwoniella heveanensis BCC8398
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Kwoniella.
Aromaticity0.08
Grand average of hydropathy-0.304
Instability index53.32
Isoelectric point8.90
Molecular weight51664.36
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09377
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.33|      36|      71|     280|     315|       1
---------------------------------------------------------------------------
  280-  315 (60.10/41.01)	VIALSAVYIAFCLTSMNNN.SASRTRTSSSQLHTLAN
  353-  389 (63.24/43.53)	IVCLYPVWETFEPTSMRHNpAAAAAHASPAHAQTHPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.17|       8|     165|      70|     104|       3
---------------------------------------------------------------------------
   61-   68 (16.68/22.45)	P..IATACVF
   83-   92 (11.49/18.11)	PylVLAACVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.90|      18|      34|     390|     407|       9
---------------------------------------------------------------------------
  390-  407 (31.46/17.29)	GQQQQQGKTSKDNTEKFG
  427-  444 (33.44/18.72)	GHPNNAGKSDKRSNPPTG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09377 with CycC domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SMRHNPAAAAAHASPAHAQTHPNGQQQQQGKTSKDNTEKFGPEEAAALVRRMIEERMVDMGHPNNAGKSDKRSNPPTGSLGNTSHGVDPLTGRKRARR
367
464










Molecular Recognition Features






MoRF SequenceStartStop




1) LVRRMIEERMVDMGH
414
428