<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09373

Description Uncharacterized protein
SequenceMPTHRYPPGVNPYAPLPTSSSMSGVGSSSNRVPNQHPLKSGRPSSLSRAGVTAPKVLLDDADIEDFAPPEWRTVMNSRVDLGYPDFYPSRPGFDQPEDVLTEENVKNGFSGRNFVAVGAEVFSMHGPIHQHLSSGGLNLLQQLGKELIEKRQELMPQVGERTFRIPVRVTYNDTKRLQFLADLSNPNVPLHRLMRTPVPHGFKGVELLDAMFSPSTGPGTGHNRNPSGGVKLSSEPIPLDRALWFIRVLGANEISAHRGRTQPLAVATPVPVSAPSPAVATPSSTTTIAATPTLPVTSNDWYTQEFTNTFITWLRIQLGQLALPNSNKTVIKSGAPPPKGPASVLNDENGRAKWLAKWDYSARLMRELYNRHLLSSRILSGWLSDYLSHSNLAQLGFVAQMIGEHLPDMAKHMSNARYCVRAACEKLKEIRSFPATASLAKVEAMLISIIKSLYETSHEALLSPTTWRLHSDLLQTLLPSTSNTWDDLRRRNEALWFSTIVDERSSSPRRQQMAEIQKLDSICEDTNMIDLTKSFFDGTSSASLNNPDILKLEEKIFILLNWAMGLFQLGSHRPYAVYTILKHWHNQHEEHQSKQPRPHVIEFFPILYKWLDTSAAARKEENVHAIGITIGELTRQGIFSYGQYLQALISKGQTARSSGGTGRKSHHLALLKAMPIFVVAKDLLHQRRIALCGDDLEARKREENDETQLMDQFKDEVMEYVPEVFGLKRYKRSAELREVLDYQLPTSSKMSRYLYVQARFWLAPDAGFQLKARGDTPAMDASTFARVLQVFRSCRGFATIADFVIRALQDSEDDAILDVILDTVRRDADVWTSMDGWSRLGDRLLDRYHGLQTQGRDHRRTLDFLVMLADKGRLTPDEQEEVTHLEEEMPKPATEDIPAKLDFKESLHGLQQALVHGREEAAVALAPKLFTRHGSFSNWSTPWWTAIIDLLQHPAHQHANSGILRTTISHIVAVEKDTRNALNPLINGWLGKMTPSALIDMLGRRAGPTICQLLLELVYERCLSVVTVLDRLVYPIWKYASTTVLVPRKRLSGKQTQAVVSSVNIAAQVLVSPPLAHSFSSLTVFQSIILLASRQAVFCGTNVQGIIRHVPLLVVLERIGNLPETTSETARATIRRLAMTAEFKTAAFRNLNVLKDAFLSSEWTKPSLDAGLEDRMVDTLKLIMSEKPLNALTPAPKPGLPNLDNNARFSAWRWTRIVLEMRVEFKGLAMRIANGEEVAEARQTLNRLVHVTLDRETTPDDTDLLCEAFGGMDTVVTQEILAAGMDRLSSLLSQAIGAETQHQLEGFIRSIDQVLRILDSTNRQPKQVISDHVVLAARHKLLDLLAVALQSTERNISSDQDLMIHHDISPPQPGDFLKVVLNLLKFALGILAADPSSPSMPKPNFPHLAAMFFKVVVACHTALVIDSTQMMCDMLAYIIDCTPPQSRLACQIALLGETTPTAVQAILADMPIVSSILPHLSPVMRNTALVGSDVTDDHPSDSALPLDDRKWELFEQMEPRPRQIKHQDLYLSSASLKDTSSIPLALFSPTMTRDALPGTATTWSDELTDNNEKEDEACPWEELASERDLGDGFAGQPGFAKQSATSMFDGVEEYNIAEPPTPPSSHESSDESASAVLLSAQPRRMSTRISTHALPHGAENYNPSNGASSNTSTSKRGSGSNKDPISIDEDDSDDEPETVDPRPAAKRPRTSSKSTASNTAGRQTTGGKAPAGGARKTTGGKGVSRKATSGKSVKGTGSKAPKGGGRRKSQAD
Length1772
PositionKinase
OrganismKwoniella heveanensis BCC8398
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Kwoniella.
Aromaticity0.06
Grand average of hydropathy-0.323
Instability index45.67
Isoelectric point6.73
Molecular weight195799.41
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09373
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.39|      43|      67|    1467|    1512|       1
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 1467- 1512 (71.58/47.80)	LADmpiVSSI.LPHLSPVMRNTALVGSDVT.DDHPSDSALPLDDR.KWE
 1536- 1581 (64.81/35.49)	LKD...TSSIpLALFSPTMTRDALPGTATTwSDELTDNNEKEDEAcPWE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.83|      35|      48|    1310|    1346|       2
---------------------------------------------------------------------------
 1310- 1346 (52.40/36.56)	SIDQVLRI.LDSTNRQPKQVIsdHVVLAARHKLLDLLA
 1357- 1392 (53.42/31.60)	SSDQDLMIhHDISPPQPGDFL..KVVLNLLKFALGILA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     190.71|      30|      48|    1655|    1684|       3
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    7-   33 (44.76/24.98)	PPGVNPYA...P...L........PTSSSMSG..VGSSSNRVP
 1610- 1635 (19.73/ 6.12)	..GVEEYNiaePPTPP........SSHESSDE..SASA.....
 1655- 1684 (53.99/31.93)	PHGAENYN...PSNGA........SSNTSTSK..RGSGSNKDP
 1693- 1730 (36.41/18.69)	DDEPETVD...PRPAAkrprtsskSTASNTAG..RQTTGGKAP
 1731- 1761 (35.82/18.24)	AGGARKTT...GGKGV........SRKATSGKsvKGTGS.KAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      52.33|      10|      48|     183|     192|       4
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  183-  192 (18.85/10.31)	LSNPNVPLHR
  232-  241 (17.61/ 9.07)	LSSEPIPLDR
  249-  258 (15.88/ 7.36)	LGANEISAHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.47|      24|      71|     683|     711|       6
---------------------------------------------------------------------------
  683-  711 (37.83/39.28)	LLHQRRIALCGD...DLEARkreenDETQLMD
  754-  780 (40.64/28.41)	LYVQARFWLAPDagfQLKAR.....GDTPAMD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.34|      50|     294|     588|     640|       9
---------------------------------------------------------------------------
  588-  640 (82.43/52.34)	HEEHQSKQPR....PHVIEFFPILYKWLDTSAAARKEEnvhAIGITIGELTRQGIFS
  884-  937 (79.91/43.70)	HLEEEMPKPAtediPAKLDFKESLHGLQQALVHGREEA...AVALAPKLFTRHGSFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.39|      28|      45|      47|      74|      10
---------------------------------------------------------------------------
   47-   74 (48.48/30.61)	SRAGVTAPKVLLDDADIED.FAPPEWRTV
   89-  117 (43.91/26.97)	SRPGFDQPEDVLTEENVKNgFSGRNFVAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.73|      42|     331|     795|     846|      11
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  795-  846 (56.82/61.89)	RGFATIADFVIRALQDseddaiLDVILDTVRrdADVWT..SMDgwSRLGDRLLD
 1135- 1178 (67.91/42.98)	RRLAMTAEFKTAAFRN......LNVLKDAFL..SSEWTkpSLD..AGLEDRMVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.84|      32|      45|    1225|    1257|      14
---------------------------------------------------------------------------
 1225- 1257 (46.54/36.75)	FKGLAmRIANGEEVAEARQTLNRLVHVTLDRET
 1269- 1300 (51.30/35.15)	FGGMD.TVVTQEILAAGMDRLSSLLSQAIGAET
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09373 with Med12 domain of Kingdom Fungi
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