<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09370
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MSLGPPPHLPSPVATPGTTTAPQPPINDGTIPMDQAMLRTELESQLLRLSQDLYELEICAGDVGTGMEDAVPNYLMKINQGFVNLSQLSSQMTDSVPHQVLEHIDRFKNPHLYTKTVITRATGENQYALGRVLGLESFRRQLHDALEEDFPEIPLPERRHQPISVKEETGTGVVSADGGIALGQAEARGQVNGDVRVKTEEGGGEGNEPPIGGVPNGSSHIS |
Length | 222 |
Position | Middle |
Organism | Kwoniella heveanensis BCC8398 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes>
Tremellales> Cryptococcaceae> Kwoniella.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.464 |
Instability index | 51.77 |
Isoelectric point | 4.81 |
Molecular weight | 23888.45 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP09370
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 52.02| 14| 182| 17| 32| 1
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17- 32 (23.30/16.33) GTTTAPQPPIndGTIP
202- 215 (28.72/13.94) GGGEGNEPPI..GGVP
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