<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09363

Description Cyclin C
SequenceMSSSFWSSSHCLHWLTTRPSLLISRQVDLQYCTPKQLYCLNIFFTQLIQKLGKRLLLRQIPIATACVFFKRFYLKNSICETNPYLVLAACVFVAAKVEETPVHIKSVVSEAKVVFNEYNIKLFPAEANKLGEMEFYLLEDLDFHLVIFHPYRALLHITGREPADAGKFPMSRVDEDHMIKKKEVEAKKKKDEESRNSMLNVPSKPSLSPSPNINNNGKDTEEVDEDEKEAKRIRRLMGRGSTEGIGEVDEGVLQISWFILNDTYRTDVHLLYPPYIIAISAIYIAFCLTSMNNSSSNSSTRTRTSSTQVQSLSTSITTNQALGLAAPPSGAAEFLAGFQVNLNVLFACVQDIICLYAIWEGFEPSSIRHQTKNLAGLGEDKEKEKEKEKFGPEQAEALVRKMIESRMIDMGHPNNAGLNQTSKRSAGTTGASASNLDNSSGIGKKRARK
Length449
PositionKinase
OrganismKwoniella bestiolae CBS 10118
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Kwoniella.
Aromaticity0.08
Grand average of hydropathy-0.306
Instability index49.57
Isoelectric point8.43
Molecular weight50272.97
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09363
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.12|      24|      49|      62|      85|       1
---------------------------------------------------------------------------
   62-   85 (43.51/27.71)	IATACVFF......KRFYLK......NSICETNPYL
   86-  112 (20.81/10.02)	VLAACVFVaakveeTPVHIK......SVVSEAK...
  113-  137 (19.81/ 9.24)	.....VVF......NEYNIKlfpaeaNKLGEMEFYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.01|      27|     165|     212|     256|       2
---------------------------------------------------------------------------
  164-  197 (35.79/21.44)	DAGKfPMSRVDEDhmikkkEVEAKKKKDEESRNS
  215-  241 (47.22/55.36)	NNGK.DTEEVDED......EKEAKRIRRLMGRGS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09363 with CycC domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DMGHPNNAGLNQTSKRSAGTTGASASNLDNSSGIGKKRARK
2) KKDEESRNSMLNVPSKPSLSPSPNINNNGKDTEEVDEDEKEAKRIRRLMGRGS
409
189
449
241










Molecular Recognition Features






MoRF SequenceStartStop




1) ALVRKMIESRMIDMGHPNNAGLNQ
2) KRIRRLM
3) TTGASASNLDNSSGIGKKRARK
397
231
428
420
237
449