<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09351

Description Cyclin-dependent protein kinase
SequenceMSLANNNPPSSASGPSSAAAAKQNLKRSVQQAFEEPADRSSGHVAYQSKVRVVDRYKVIGFISSGTYGRVYKAAGRLGQTGEFAIKKFKPDKEGEQIHYTGISQSAVREMALCSELSHINVIKLIEIILEDKCIYMVFEYAEHDLLQIIHHHTQPTRHPIPSATVKSIMFQLLNGCQYLHSNWVLHRDLKPANIMVTSAGEVRIGDLGLARLFSKPLHSLFSGDKVVVTIWYRAPELLLGSRHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRHQMQKIVDIMGLPTKDKWPLLVSMPEYANLSSLHAPVQPNGKPAGSKLESWYYSTIGQHSGTSQPASSSLGAEGYKLLAGLLEYDPDKRLTAQQALEHPFFSTGDKVSSNCFEGMKTEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDTLARPSKRMKEN
Length443
PositionKinase
OrganismPseudogymnoascus verrucosus
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Leotiomycetes incertae sedis> Pseudeurotiaceae> Pseudogymnoascus.
Aromaticity0.08
Grand average of hydropathy-0.384
Instability index42.04
Isoelectric point9.10
Molecular weight49233.72
Publications
PubMed=29295979

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP09351
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.80|      56|     279|      35|      92|       1
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   35-   92 (88.59/71.27)	EPADRSSGHVAYQ.......SKVRVVdRYKVIGfISSGTYGRVYKAAGRLGQTGEFAIKKFKPDK
  310-  372 (92.21/63.88)	EYANLSSLHAPVQpngkpagSKLESW.YYSTIG.QHSGTSQPASSSLGAEGYKLLAGLLEYDPDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     185.48|      43|      90|     131|     173|       2
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  131-  173 (76.73/50.27)	DKCIYMVFEYAEHDLLQIIHHHTQPTRHPIPSATVKSI.......MF.....QLL
  174-  221 (45.01/26.66)	NGCQYLHSNW.......VLHRDLKPANIMVTSAGEVRIgdlglarLFskplhSLF
  224-  261 (63.74/40.60)	DKVVVTIW.YRAPELLLGSRHYT.PA...IDMWAVGCI.......FA.....ELL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP09351 with CDK8 domain of Kingdom Fungi

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