Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADQQQGNVQASAFPSPPPFYQHFTEENLARVAILRAGRESDSSQKDDSPKEPELRGDLQYLQPPEPPAEGTYRSFGDLYNLNDILPSLAEQGIEQLYSPPATPSGSGAGSDPQSHSDRTLILKRIAKSLLLNFLELMGIMSVNPEQYAEKIQDLRTLFINFHHLLNEYRPHQARESLILMMEAQLARSKAETNGIESMKTKVEGILAGLGEVNIAPEEAEEYKDTKKDLEEYDSAKDVWDDLHRDYGLVEPGISS |
Length | 256 |
Position | Middle |
Organism | Pseudogymnoascus sp. 05NY08 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Leotiomycetes incertae sedis> Pseudeurotiaceae> Pseudogymnoascus> unclassified Pseudogymnoascus. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.652 |
Instability index | 64.76 |
Isoelectric point | 4.66 |
Molecular weight | 28615.53 |
Publications | PubMed=29295979 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP09322 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 157.96| 41| 81| 54| 94| 1 --------------------------------------------------------------------------- 54- 94 (72.72/38.57) ELRGDLQYLQPPEPPA...E..GT.YRS.FGD.LYN.LNDILPSLAEQGI 96- 135 (33.44/14.43) ......QLYSPPATPSgsgA..GSdPQS.HSDrTLI.LKRIAKSLLLNFL 136- 178 (51.80/25.71) ELMGIMSV..NPEQYA...EkiQD.LRTlFIN.FHHlLNEYRPHQARESL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) LRGDLQYLQ 2) PFYQHFTEENLA | 55 19 | 63 30 |
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