<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09317

Description Uncharacterized protein
SequenceMAPDRIDQNVYEDQLKDIIQDLYELMVQTTSYGNVGQGVSSKDVLQNTVAHLHASLTQLHASASSPFAAPIRVPPELIQYVDAGRNPDIYTREFVELARRGNQLMKGKKQAFGSFRDILAREMASALPEVKGDVENVVRETGGEVENAIQIAWDPTSSQALKGQAFEFLNQLREDVSGWQICLTLFTRTPQTSEVVRLVSIEIVNNAVAHQHLDEASLTFLKDSLLEYSRRVYGGSGGQQQADSASLQNKLTQTLTSVFAFSYQRGWESFFSDFLSMTCLPNSTSCDNLAGTALYLRILGSVHDEIADVFLSRTGEDQKRNNDLKDLLRERDVPKIATSWQEILTYWQGKNDTLVEMCLKVIGRWVNWIDISLVVNQNFLTILLQLIGRVAPNNGEDKVRDAAIGCLTETVGKKMKAGDKMDMIEFLNLGDIVSQLVASPALANRFGSDYDVDFAEAVAKLVNGAVFDIVKALEESADGSPTRVKADQQLLIFLPHLLRFFSDEYDEPCSTVIPSLTDLLTLFRRAQPLPAQYSSMLSPILNAIITKMRYDDTASWDDQVTETDGAEFMELRKRLEVLQKIVAAVDQTLYIDVLSNVVGNTFQSIEQRGSGVNWRDIDLALHEMYLFGELAVPNSGLYAKSQPSSVASERLIAMMQKMIESGIASYNHPAIQLQYMEICVRYCSFFENQSAFIPQVLEHFVALVHHNHVRVRTRSWYLFGRFVKHLRAILGNVAETVITSISDLLVIKAEVPKPDDEDDMSSDESDHSAGAVFTSQLYLFEAVGTIASTSTTPVDKKVLYARMVLEPLFANMEQALPAARNGNAQANLQIHHIIMALGTLAHGFSDWTPGISSAGSKAPADEISQEFNRAAEAILVALESLKSPPEIRTAARSAFTRLVGTVGARLLPQLPRWISGLLSTESSKDEMAMFLRVLDQVVFGFKTEIIGVLDSLLSPLLMRIFNSLGEAVSGTDDEIQLGELRREYLTFLQVILNNDLASVLVSETNQGLFDVLLISVETLAKNVNNGTGHLAASRMSFSILAKMAQLWGGPDVATPSHYPETATPAPTPAFPGFDQFLINRFNPVCWEVLRNPDFRPYQDAQAKSVLTEIAGLQQIIYSKTGMLFIEHLQQSFFPSMGFDGSDIIRSMTTSNDRKVFANFLVAYLKQRA
Length1168
PositionMiddle
OrganismPseudogymnoascus sp. 05NY08
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Leotiomycetes incertae sedis> Pseudeurotiaceae> Pseudogymnoascus> unclassified Pseudogymnoascus.
Aromaticity0.08
Grand average of hydropathy-0.059
Instability index40.95
Isoelectric point5.05
Molecular weight129670.10
Publications
PubMed=29295979

Function

Annotated function tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Involved in pre-tRNA splicing, probably by affecting the interaction of pre-tRNA with splicing endonuclease. 
ECO:0000256	RuleBase:RU366037
ECO:0000256	ARBA:ARBA00004073
GO - Cellular Component
cytoplasm	GO:0005737	IEA:UniProtKB-SubCell
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
small GTPase binding	GO:0031267	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro
tRNA binding	GO:0000049	IEA:UniProtKB-UniRule
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tRNA processing	GO:0008033	IEA:UniProtKB-KW
tRNA re-export from nucleus	GO:0071528	IEA:UniProtKB-UniRule

Interaction

Binary Interactions











Repeat regions





Repeats

>MDP09317
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     193.35|      73|     415|     535|     611|       1
---------------------------------------------------------------------------
  535-  611 (113.29/90.47)	SMLSPILNAIITKMRYDDTASWDDQVTETdgaEFMELRKR.........................................................................................................................................................................................................................................................LEVLQKIVAAVdQTLYIDVLSNVVG....NTFQSIEQRGSG
  645-  681 (45.78/26.35)	SVASERLIAMMQKMIESGIASYNHPAIQL...QYMEICVR..................................................................................................................................................................................................................................................................................................
  931-  970 (34.27/17.09)	........................................ycsffenqsafipqvlehfvalvhhnhvrvrtrswylfgrfvkhlrailgnvaetvitsisdllvikaevpkpddeddmssdesdhsagavftsqlylfeavgtiaststtpvdkkvlyarmvleplfanmeqalpaarngnaqanlqihhiimalgtlahgfsdwtpgissagskapadeisqefnraaeailvaleslksppeirtaarsaftrlvgtvgarllpqlprwisgllstesskdemamfLRVLDQVVFGF.KTEIIGVLDSLLSpllmRIFNSLGEAVSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     153.17|      49|     156|      13|      62|       2
---------------------------------------------------------------------------
   13-   62 (79.99/59.28)	DQLKDII...QDLYELMVQTTSYGNVGQGVsSKDVLQNTVAHLH...ASLTQLHAS
  170-  224 (73.18/49.31)	NQLREDVsgwQICLTLFTRTPQTSEVVRLV.SIEIVNNAVAHQHldeASLTFLKDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.03|      49|     171|     300|     348|       3
---------------------------------------------------------------------------
  300-  348 (88.15/63.00)	GSVHD......EIADVFLSRTGEDQKRNNDLKDLLR....ERDVP..KIATSWQEILTYWQ
  464-  524 (68.88/47.49)	GAVFDivkaleESADGSPTRVKADQQLLIFLPHLLRffsdEYDEPcsTVIPSLTDLLTLFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     164.42|      54|     171|     700|     760|       4
---------------------------------------------------------------------------
  700-  760 (79.04/72.10)	FVALVH.HNHVRVRTRSWYLFGRFVKHLRAILgnvAETVITSISDLLviKAEVPKpdDEDDM
  875-  929 (85.38/55.83)	LVALESlKSPPEIRTAARSAFTRLVGTVGARL...LPQLPRWISGLL..STESSK..DEMAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.57|      24|     628|     359|     395|       7
---------------------------------------------------------------------------
  366-  395 (39.10/51.42)	VNWIDISLVVNQNFLtillqlIGRVA.PNNG
  612-  636 (42.48/22.54)	VNWRDIDLALHEMYL......FGELAvPNSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09317 with Med10 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA