<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09293

Description CMGC/CDK/CDK8 protein kinase
SequenceMSLANNNPPSSASGPSSAAAAKQNLKRSVQQAFEEPADRSSGHVAYQSKVRVVDRYKVIGFISSGTYGRVYKAAGRLGQTGEFAIKKFKPDKEGEQIHYTGISQSAVREMALCSELSHINVIKLIEIILEDKCIYMVFEYAEHDLLQIIHHHTQPTRHPIPPATVKSIMFQLLNGCQYLHSNWVLHRDLKPANIMVTSAGEVRIGDLGLARLFSKPLHSLFSGDKVVVTIWYRAPELLLGSRHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRHQMQKIIDIMGLPTKDKWPLLVSMPEYANLSSLHAPVQPNGRPAGSKLESWYYSTIGQHSGTSQPASSSLGAEGYKLLAGLLEYDPDKRLTAQQALEHPFFSTGDKVSSNCFEGMKTEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDTLARPSKRMKEN
Length443
PositionKinase
OrganismPseudogymnoascus sp. WSF 3629
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Leotiomycetes incertae sedis> Pseudeurotiaceae> Pseudogymnoascus> unclassified Pseudogymnoascus.
Aromaticity0.08
Grand average of hydropathy-0.387
Instability index43.80
Isoelectric point9.10
Molecular weight49285.80
Publications
PubMed=29295979

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09293
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     352.77|      94|     162|     121|     226|       1
---------------------------------------------------------------------------
  121-  223 (143.85/127.19)	VIKLIEIILEDKCIYMVFEYAEHDLLQIIHHHTQPTRHPIPPATVKSIMFQLLnGcQylHSNwvlhrDLKPANIMVTSAG.EVRIGDLGL...ARLFSKPL..HSLFS.G
  224-  269 (71.07/42.82)	..........DKVVVTIW.YRAPELLLGSRHYT.PA...IDMWAVGCI.........................................F...AELLS..L..RPIFK.G
  290-  388 (137.85/98.03)	IIDIMGLPTKDKWPLLV.SMPEYANLSSLHAPVQPNGRP.AGSKLESWYYSTI.G.Q..HSG.....TSQPASSSLGAEGyKLLAGLLEYdpdKRLTAQQAleHPFFStG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09293 with CDK8 domain of Kingdom Fungi
Unable to open file!