<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09209

Description Uncharacterized protein
SequenceMSVYNHLIYDMKKKRPLKRPRLGPPDIYPQEAKQKEDELTSSNVKQGFTLLPHMEEFGTARNYNVTASKVGSYFNAILARKEELMTLPDSGRKKQQINPKDNFWPVTARTKATLDTWFKDLAGTKPLLSLAKKAPSFNKKEEIFAMLCENQVSMQRAAWFIKLSSAYTVAVSEAKIKKRQMPDPATEWTGTMIKFMRELIPKLHEHYYQGILPEKVQSSSNSSSTPTSSASSTAITTVPTPLASPASSMHSPGNLGSTPTSSLLAPPSPQDEHKLALKQWNYCIQLSKYMYEEGLLDKHEFLNWILDLLDKVRSQPTDDGLLKLFLPLTLQYMSDFVQSERLSRRLAYLVCKKMGHMINSAVENGHVFAQDASMTPANGTAIKQENPEPQNADASKTQDTQDSKENVKSGSNKVVANGVHATNPYTFFSDYMSCPHHRDLILQWSSIIQVITIECSTSLVWCGIGENRASSIFIGSPLDHLPISPSSLPMPPRFTEANEEIRKQLRIVEESIKTRSKHAEARWCTDKWQSVTGNTGNRILSTLDALDSHCFDRMDTSNSLETLYGKIFPPNSTPGTTSGGNNGNSTGKEHSSGSEGKEAKLEYDPNQDAPIIKILCEWAVSWQRWGEHRAMAVAWLLDKRQTEVTASNENEATNGNSDDKDSISSGAGVSGSPVFQKILMNFLDNDAPVLEENGSPQNRSQFTNLVHLFSELIRHDVFSHDGYMCTLIARGDLTTKGISATQPHTNVIPPGPISNPTKTSPGMHTGLDEDVFAGIEFKSKIEEFDDSNVDDDLDKLLQHIKSDQQNSLDAPD
Length812
PositionKinase
OrganismPhlebotomus papatasi (Sandfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Psychodoidea> Psychodidae> Phlebotomus> Phlebotomus.
Aromaticity0.07
Grand average of hydropathy-0.566
Instability index49.14
Isoelectric point6.06
Molecular weight90334.66
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09209
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     229.11|      70|     216|     246|     392|       1
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  246-  328 (106.65/178.84)	ASSMHSPGNLgsTPTSSLLAPPSPQDehkLALkQWNYCIQL.....SKYMYEEGLLDKHEFLNWILDLLDKVRSQPTDdgllklfLPL
  416-  490 (122.46/55.79)	ANGVHATNPY..TFFSDYMSCPHHRD...LIL.QWSSIIQVitiecSTSLVWCGIGENRASSIFIGSPLDHLPISPSS.......LPM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.39|      23|     474|     138|     161|       2
---------------------------------------------------------------------------
   98-  119 (37.08/23.58)	NPKDNFWPVTARTKATLD..TWFK
  138-  161 (37.42/28.78)	NKKEEIFAMLCENQVSMQRaAWFI
  606-  625 (33.90/20.93)	NQDAPIIKILCEWAVSWQR..W..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.19|      21|      70|     573|     593|       3
---------------------------------------------------------------------------
  573-  593 (39.64/22.70)	TPGTTSGGNNGNSTGKEH.SSG
  645-  666 (32.55/17.39)	TASNENEATNGNSDDKDSiSSG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09209 with Med12 domain of Kingdom Metazoa
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