<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09196

Description Poly(rC) Binding Protein
SequenceMLQMNALTESLMSNAFDLMEGSSVAQQFLENHMGYIRQRQQLTQLEQQQEAQNLFHINAQQQQQKQRELHIMPTNLNHNANGNNVTVLSRSTISPLQQQQQQQQQQQQQQPQTQQLLQQPTSTANAIISNLTPNASSSATILTQQLQQQQQQQQQQQQQQQHHTHQHPHQHAASSTSPFKSCWCLGDTTYHMKILVPAVASGAIIGKGGETIASLQKDTGARVKMSKSHDFYPGTTERVCLITGSVEGIMTVLDFIMDKIREKPDLSAKILEAESKQTQERDKQVKILVPNSTAGMIIGKGGAYIKQIKEESGSYVQISQKPKDISLQERCITIIGDKENNKNACKMILSKIVEDPQSGTCLNVSYADVSGPVANFNPTGSPYATNQNAINSSTASLNSTLGTTIGGAATAAGLLVNGTGINFSLNLSAPNPAPNLAVATQLLEHIKVALRGYGYTETATTEVCAALGVLAKYGVLGMGVGLPHANGAHTALGSYLDMSTLNQQTAAATAATAGNVFGAVGQVNLEQYAAAAAAAVATRPAQSLDVAAAAAQFDPFRHLSTAAASAAQATTPVSLNNNSFGLTAATGTPSTAPTLGATAAHTLTGLSKSPTPGDLSAKDSKNVEIPEVIVGAILGPNGRSLVEIQHVSGANVQISKKGIFAPGTRNRIVTITGQPSAIAKAQILIEQKINEEETKRARQIPLTTVVN
Length707
PositionTail
OrganismGlossina morsitans morsitans (Savannah tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.04
Grand average of hydropathy-0.294
Instability index46.66
Isoelectric point8.32
Molecular weight75056.65
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
RNA binding	GO:0003723	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09196
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     195.07|      48|      50|      60|     109|       1
---------------------------------------------------------------------------
   36-   95 (69.08/29.45)	IRQR.QQLTQLEQQQeaqnlfhinaQQQQQKQRELHiMPTNlNHNANGNNVTVLSRSTISP
   96-  141 (76.06/27.30)	LQQQ.QQQQQQQQQQ.........qPQTQQL...LQ.QPTS.TANAIISNLTPNASSSATI
  142-  173 (49.92/16.04)	LTQQlQQQQQQQQQQ..........QQQQQHHTHQH..PH..QHAA...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     230.87|      38|      42|     454|     491|       2
---------------------------------------------------------------------------
  354-  380 (35.54/15.89)	....EDPQS......GTC..LNV..SYA.....DVS...GP.VANFN.......PTG
  384-  411 (38.89/18.08)	A.TNQNAIN......SSTASLN.....S.TLGTTIG.........GA.......ATA
  413-  445 (24.13/ 8.45)	G.LLVNGT.............GI..NFS..LNLSAP...NP.APNLAvatqlleH..
  454-  491 (65.73/35.59)	G.YTETATT......EVCAALGVLAKYG.VLGMGVG...LP.HANGA.......HTA
  493-  535 (32.47/13.89)	GsYLDMSTL......NQQTAAATAATAGnVFG.AVGqvnLEqYAAAA.......AAA
  568-  602 (34.10/14.95)	Q.AT.TPVSlnnnsfGLTAATGTPSTAP.TLG...........ATAA.......HT.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     325.07|      68|      91|     193|     260|       3
---------------------------------------------------------------------------
  193-  260 (116.37/67.10)	KILVPAVASGAIIGKGGETIASLQKDTGARVKMS.KSHDFYPGTTERVCLITGSVEGIMTVLDFIMDKI
  286-  352 (107.00/61.16)	KILVPNSTAGMIIGKGGAYIKQIKEESGSYVQISqKPKDI..SLQERCITIIGDKENNKNACKMILSKI
  625-  689 (101.70/57.80)	...IPEVIVGAILGPNGRSLVEIQHVSGANVQIS.KKGIFAPGTRNRIVTITGQPSAIAKAQILIEQKI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09196 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NLFHINAQQQQQKQRELHIMPTNLNHNANGNNVTVLSRSTISPLQQQQQQQQQQQQQQPQTQQLLQQPTSTANAIISNLTPNA
2) SATILTQQLQQQQQQQQQQQQQQQHHTHQHPHQHAASSTSP
3) TAPTLGATAAHTLTGLSKSPTPGDLSAKDS
53
138
591
135
178
620










Molecular Recognition Features






MoRF SequenceStartStop




NANANA