<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09195

Description Uncharacterized protein
SequenceMCARNTQLLLYIHIYIVIQYYQHRHHQQNNSKNVKLQFCCYRVLSSTRLTGRSLRNFELNMASIDQKKERKKPLPTLMVGDQDSLRSCRHIRYCCGWLAAAAATAAAAAVVVVVFNTNSSTNSTTHNKMSSPPPLPPPNPSLSCNYYNANTNQHHHQLQQKSQRAFNPYVDEMEDDNISLYSTTASIITARDHPYNNSQRPLLADRKPQLLLGSNANNNKKKTKNQTTANQQSSPKLSQNHHQQQQQQQQQPKQQQQQQQQQQQQQQEQKQKPEQKSYISPYVQQQKRDSVKGLHGFNDFDILSQQYNKHLQSPHIGYPYGSPPSPNSNSTAVDFVFDSADSTTTPIYRNNYASISTPLTVTTCYGNAVCDYGSTLPTSAMTEVNAIDYYRSNTNVDAINKLSRFEDDFCNRRNINFSKIDQKLTTSDDTNLYEGPFIFGIPPEQQTDFTRLGINGRSFDDITSCKAVITNNGKQKLDKSMKQTVTQTSNSDTSSTTRDDSSTSNDSNGDPKGATKFLLRKRKTKKITKEGKPFNVVVEKPTIKCVLVGDCAVGKTNLILSYLENRFNTEHIPTASDIYNADVMVNDSPVHLTLCDTAGQDTLDPLRELCYPDSDVFLLCFSIAKPKTFHAIKNKWAPKFAKTKASLILVGTQADLRDNPNVLNKLQSNGEKPISHADAWDLATTIGAKYIETSSATQDKVKEVFDTAIWEGLAPTNLPPTPPPLWKKLFCLV
Length733
PositionKinase
OrganismGlossina morsitans morsitans (Savannah tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.08
Grand average of hydropathy-0.733
Instability index46.80
Isoelectric point9.01
Molecular weight82401.39
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
GTP binding	GO:0005525	IEA:InterPro
GTPase activity	GO:0003924	IEA:InterPro

GO - Biological Process
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09195
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.23|      16|      16|     243|     258|       1
---------------------------------------------------------------------------
  226-  241 (26.02/11.75)	QTTANQQSSPKLSQNH
  243-  258 (32.15/16.17)	QQQQQQQQQPKQQQQQ
  260-  275 (30.06/14.66)	QQQQQQQQEQKQKPEQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.06|      13|      15|     359|     372|       2
---------------------------------------------------------------------------
  359-  372 (20.69/17.57)	L.TVTTCYGNAVcDY
  376-  389 (17.37/ 8.10)	LpTSAMTEVNAI.DY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.12|      17|      19|     391|     407|       3
---------------------------------------------------------------------------
  391-  407 (29.12/23.57)	RSNTNVDAIN.KLSRFED
  412-  429 (25.00/19.01)	RRNINFSKIDqKLTTSDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.11|      14|     128|      19|      32|       4
---------------------------------------------------------------------------
   19-   32 (29.27/16.93)	QYY.....QHRHHQQNNSK
  145-  163 (22.84/11.66)	NYYnantnQHHHQLQQKSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.48|      21|     569|     114|     138|       5
---------------------------------------------------------------------------
  114-  138 (35.84/27.66)	VFNTNSSTNSTTHNKmsspPPLPPP
  704-  724 (42.64/22.78)	VFDTAIWEGLAPTNL....PPTPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.70|      16|      19|     482|     498|       7
---------------------------------------------------------------------------
  483-  498 (25.76/14.27)	QTVTQTSNSDTSSTTR
  501-  516 (26.93/10.48)	SSTSNDSNGDPKGATK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.79|      15|      19|     308|     326|       8
---------------------------------------------------------------------------
  308-  326 (26.32/21.32)	NkhlqSPHIGYPYGSPPS...P
  329-  346 (21.47/ 8.79)	N....STAVDFVFDSADStttP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09195 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KLDKSMKQTVTQTSNSDTSSTTRDDSSTSNDSNGDPKGAT
2) LYSTTASIITARDHPYNNSQRPLLADRKPQLLLGSNANNNKKKTKNQTTANQQSSPKLSQNHHQQQQQQQQQPKQQQQQQQQQQQQQQEQKQKPEQKSYISPYVQQQKRDSV
3) TNSTTHNKMSSPPPLPPPNPSLSCNYYNANTNQHHHQLQQKSQRAFNPYVDEMEDDNI
476
180
121
515
291
178










Molecular Recognition Features






MoRF SequenceStartStop




NANANA