<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09176

Description Uncharacterized protein
SequenceMNNRQILDLTLRLSQALDQNYDVVNMDAVLSVITTLENTTVTKAHLETTRLAKYINQLRRRTKCEHLARRAKSLLKRWREMVGIQQAHQNEATLTTTIHVNNTPVISGLSMSNFGAEPSQPPSQTTQMRFQSDSANYSLQSNQNYAQSQRPSQFHSQIERNLPNDLSYSRNIDVNSDFLRNTTSNSAPISSLTKSVNPSSTKRLNRNAHEQKQQQPTSFANLLSGLNASSDSACGNSKGSSVKPHKTIAKRDTDTVQAVETLIIDHSSNSNSEIVFMPSNCTNCTKTANVPPIIIDLQDTNSVETNEHHLVVDPKVIGISSSSKSRKSRINKKRREATNSIEFDVASLDNDCVSKPFIGETKSCSVCPISSISEILSLSNSSMSSVFPMEKIMVNANCSVSKTNNQSQLADKVPKSDLTFAGKFKQASGQPTCDRVSEYKCNRDVIIDGVSSTASNNNHSSSPNVLDMKTSPKTSTKFTHFGGVGINSNDSTSNSRISQFELGKPEKFPHVFYNTSQNNEDTSLQKQQCAYKHENYTTSTYLKDSVVPILEMKQAVSRICTTDEVKVPKKRGRKKGSKGIDSIIAKEVSLSSEMLISSLGTGVKKVKTTKELYAEIKSRKLVAEASEVAEVVISPSTSISSQLQSQQQAFSGPESSCSEPSLHSPRTLDACSTNATMSTVATRSTPDKSIAETHPDDSFTLTDDSILPSKMVSVTPRENHTQDANSNSCSDIKSESLENASSVAVTTVNSISAIRAQICELTKKFVPVSLVKFTQDSLPCTCTIVEITPEKFRGVDKFKKVDEDSTDINQTNSNITVALEQFQMPVAAASDEFVASKLVQHDIITNSQLSSSLTSCLTPRQKHKKSIFDFDFDDNEEDPLHTIIADLAANKKSGTAWSGDEERSNEACNKRSVVENEIGKQMVISKSTSHRQQPNQNDSSPTPHSKIPIYQIQEDPKCRAKYRFEIETQQITGFHIKALHNTFIENVNGNWNHSCELKNVIVENDYLDKKKMVDGYDVVPPYGSLIKERILKDLTAVIFTSNYKRKRNSLLIEKLKNLPFLGVARTTLLGNSIHRNNMETRSTFSMLDEEKQQLEKREVSTFANYVGSADPVSKDDVNLFVNLSDSSKISPIRAGDNVSDQKTTAPLLVLAAPHLNRKYIESDDNSVSCLRRRRKSEGNASSDNETKLINEPKYYDKENTRCEQDKEGFWKSKYRKRKIMERITLSKHECRRTIKRLKIAANGDIATNKQIALSNTNTNSTDEEEDLSEIDSHFINENSVVVESNDDEDEDDKMDNCVSENRNLAAYDEGSNECGGDFHEVIARSSNSTSIVLTIKKTPSKSKFRTNPYANSSQNFVNVGKNMYTQDRYIEPKGNSALKASSIKAEENHLQQEKTDCKLTSKFQREDDIKTLAKQVSIKGSLEKKMGSSKENLHNQLFFSEELCPSISDDVIDFSSEGEVGSAHLENDKGGCYKKLAEAHEELSHIKLSCEFNTKQLQTTPPPSESGSSNTSINVCHRDCDDNGSCDQRIDDDDLPLENNNLLSSFNNIYYFSSQEKLGHASNQGTDSPSLQQHNKLMIEQIPNAICDVYSVYTTENHSGNYINLKGLVDNSACAKKNFLDPPDDINNDSGSGGSNTWDEEDRQLRQQVKSKTKEVDQSKFSVPYEEYRIGVRAFDKNTPQHGNCSRLQQFKEWHEVLQLHSYNDELLTVLPYVVLE
Length1717
PositionUnknown
OrganismGlossina morsitans morsitans (Savannah tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.05
Grand average of hydropathy-0.717
Instability index50.15
Isoelectric point6.25
Molecular weight191363.66
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09176
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     983.11|     321|     355|     886|    1234|       1
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  886- 1223 (493.68/353.57)	DLAANkKSgTAWSGDEERSNEACNKRSVVENE.IGKQMVISKSTSHRQQPNQNDSSPTPHSKIPIYQiQEDPKCRAKYRFEI.ETQQITG..FHIKALHNTFIENVNGNWNHSCELKNViVENDYLDkkkmvDGYdVVPPYGSLIKERILKDLTAVIFTSNYKRKRNSLLI..EKLKNLPFLGVARTTL...LGNSihRNNMETRSTFSmldEEKQQLEKREVSTFAN..YVGSADpVSKDDVNLFVNLSDS.SKISPIRAGD..NVSDQKTTAPLLVLAAPH..LNRKYIESDDNSvSCLRRRRKSEGNASSDNETKLINEPKYYDKENTRCEQDKEGF.WKSKYRKRKIM.ERI
 1244- 1582 (489.43/285.16)	DIATN.KQ.IALSNTNTNSTDEEEDLSEIDSHfINENSVVVESNDDEDEDDKMDNCVSENRNLAAYD.EGSNECGGDFHEVIaRSSNSTSivLTIKKTPSKSKFRTNPYANSSQNFVNV.GKNMYTQ.....DRY.IEPKGNSALKASSIKAEENHLQQEKTDCKLTSKFQreDDIKTLAKQVSIKGSLekkMGSS..KENLHNQLFFS...EELCPSISDDVIDFSSegEVGSAH.LENDKGGCYKKLAEAhEELSHIKLSCefNTKQLQTTPPPSESGSSNtsINVCHRDCDDNG.SCDQRIDDDDLPLENNNLLSSFNNIYYFSSQEKLGHASNQGTdSPSLQQHNKLMiEQI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.10|      27|      28|     112|     138|       2
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  112-  138 (50.75/28.13)	SNFGAEPSQPPSQ.TTQM.RFQSDSANYS
  141-  169 (41.35/21.56)	SNQNYAQSQRPSQfHSQIeRNLPNDLSYS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.10|      23|      32|     344|     366|       3
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  344-  366 (41.82/26.93)	DVASLDNDCVSKPFIGE....TKSCSV
  374-  400 (35.29/21.43)	EILSLSNSSMSSVFPMEkimvNANCSV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     270.69|      87|     220|     183|     274|       4
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  183-  274 (131.23/88.06)	TSNSapiSSLTKSVnPSSTKRLNrNAHEQKQQQPTS......FANLLSGLNASSDSACGNSKGSS..VKPHKTIAKRDTDTVQAVETLIIDHSSNSNSEI
  403-  497 (139.45/78.53)	TNNQ...SQLADKV.PKSDLTFA.GKFKQASGQPTCdrvseyKCNRDVIIDGVSSTASNNNHSSSpnVLDMKTSPKTSTKFTHFGGVGINSNDSTSNSRI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.02|      18|      20|     718|     735|       5
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  718-  735 (32.35/16.38)	ENHTQDA..NSNSCSDIKSE
  738-  757 (23.68/10.13)	ENASSVAvtTVNSISAIRAQ
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.85|      17|     283|     505|     521|       6
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  505-  521 (32.01/20.69)	PE.KFPHVFYNTSQNNED
  527-  544 (25.84/15.15)	QQcAYKHENYTTSTYLKD
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.50|      18|      32|     651|     668|       7
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  651-  668 (33.04/15.12)	SGPESSCSEPSLHSPRTL
  684-  701 (30.45/13.39)	STPDKSIAETHPDDSFTL
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.74|      34|     216|     547|     581|       8
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  547-  581 (53.93/38.37)	VPILEMK...QAVSRICTTDEVKVPKKRGRKKGSKgID
  766-  802 (54.81/34.03)	VPVSLVKftqDSLPCTCTIVEITPEKFRGVDKFKK.VD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09176 with Med26 domain of Kingdom Metazoa
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