<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09142

Description Uncharacterized protein
SequenceMAKLSTILRLMRHNSLKSIHLRSPSSLQIIDLQHRRYHDQGGSNERNWWDIPKNQKFLILTTGDSSVEAAEKYDPNIAKQHETVRQDLPTYKTEEISAHNNENTGVWVTYGIGVYDITQFVPKHPGSDKVMLAAGGAIDPFWHVFQQHNTPEVLTLLETFRIGNLNPEDQVSTRDMGDPWSGEPRRHPILKPAAMKPFNAEPTPSILVDSFLTPNEFFYVRNHLPVPEIDEKTYEIEFEVEGVKKIKRMTLKDLKKLPKHTVTAAIMCGGNRRSEMDAVKNVKGLSWGPSAVGNAEWSGARLCDILAKLGVNSDEVRHVHLEGLDTDPTATYYAASIPLAKAMDPRGDVILAYEMNGQPLSRDHGFPVRAIVPGSVGARNVKWLGRIFVSNEESDSHWQQKDYKGFSPSTDWDTVDFSKSPAIQNMPVTSAICSPMPGEKLSVKDGYITVKGYAWSGGGSRIVRVDITCDAGETWQVAELEQEDTTKAPAGRAWSWTLWTAKIPVPKNAKEVEIWSKAVDSNYNVQPETFKNIWNLRGVLSNAYSRVKVQIVQFFWEDATATSPEMDYDFKMRTQAERTKVEDLFEFEGCKVGRGTYGSVYKAHRKEGNDTKDYALKQIEGTGLSMSACREIALLRELKHVNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYANCSLVKYMERHKIKSDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPLPTQDVFAGCSIPYPKREFLTDDDQEEKSDNKRQNQQNIQQQQNNTGQSTSHDHNKRVRLSGPTGHPQQNTQMNQQQDFHHQQTQQQQMMFNNTQQQQNNFQQRF
Length1009
PositionKinase
OrganismLutzomyia longipalpis (Sand fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Psychodoidea> Psychodidae> Lutzomyia> Lutzomyia.
Aromaticity0.09
Grand average of hydropathy-0.615
Instability index43.85
Isoelectric point7.26
Molecular weight115442.44
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
molybdenum ion binding	GO:0030151	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
sulfite oxidase activity	GO:0008482	IEA:UniProtKB-EC

GO - Biological Process
sulfur compound metabolic process	GO:0006790	IEA:UniProtKB-UniPathway









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09142
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.11|      27|      36|     265|     291|       1
---------------------------------------------------------------------------
  265-  291 (49.79/29.85)	AIMCG..GNRRSEMDAVKNV..KGLSWGPSA
  300-  330 (37.33/20.70)	ARLCDilAKLGVNSDEVRHVhlEGLDTDPTA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     143.61|      37|      37|     913|     949|       2
---------------------------------------------------------------------------
  856-  901 (33.28/16.59)	.CSlVKYM..ERHKI...KSDSKAfhllQKlllmDPNKRiTS..EQAMQDPYFS
  913-  949 (68.43/41.83)	GCS.IPYP..KREFL...TDDDQE....EK....SDNKR.QN..QQNIQQQQNN
  951-  992 (41.90/22.78)	GQS.TSHDhnKRVRLsgpTGHPQQ....NT....QMNQQ.QDfhHQQTQQQQ..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.56|      22|      36|     433|     456|       3
---------------------------------------------------------------------------
  433-  456 (37.38/38.62)	CSpmPGE.....KLSVKDGYITVKGYAWS
  469-  495 (35.17/26.61)	CD..AGEtwqvaELEQEDTTKAPAGRAWS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.61|      33|      36|     686|     719|       5
---------------------------------------------------------------------------
  660-  681 (28.94/14.46)	..........LLFDYAE...HDLWHIIKFH..RAAKA
  686-  719 (57.09/40.91)	VMvPKGMVKSLLYQILD.GIHYLHSNWVLH..RDLKP
  724-  757 (42.57/25.23)	VM.GEGNERGRV.KIADmGFARLF.NAPLKplADLDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.07|      33|     412|     387|     421|       7
---------------------------------------------------------------------------
  387-  421 (59.67/39.98)	IFVSNEE.....SDSHWQQKD....YKGFSPSTDWDtvDFSKSP
  798-  839 (56.40/32.11)	IFHCRQEdiktsNPYHHDQLDrifnVMGFPQDKDWE..DIRKMP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.09|      27|      56|     137|     167|       8
---------------------------------------------------------------------------
  137-  167 (44.46/32.98)	AIDPfwhvFQQHNTPEVL..TLL...ETFRIGNLNP
  194-  225 (41.63/20.86)	AMKP....FNAEPTPSILvdSFLtpnEFFYVRNHLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.66|      17|      35|     573|     589|      10
---------------------------------------------------------------------------
  573-  589 (28.63/21.30)	RTQAERTKVEDLFEFEG
  605-  621 (29.03/21.71)	RKEGNDTKDYALKQIEG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09142 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IPYPKREFLTDDDQEEKSDNKRQNQQNIQQQQNNTGQSTSHDHNKRVRLSGPTGHPQQNTQMNQQQDFHHQQTQQQQMMFNNTQQQQNNFQQRF
916
1009










Molecular Recognition Features






MoRF SequenceStartStop




NANANA