<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09131

Description Uncharacterized protein
SequenceMSTAAASSADHCHPHHHDHHVHFDESAIKENLEADNSIVYQKSGEDGVLVHLGFLQINHRYLLELQLPSTVSPAFLFGERIALSRDERCLPNVNCKYIEFTGKVGGHYDLKVEFLAHKEKLLREELHLVNVQNFEEKLKLVLSARVLGRGKGTPMLRNGIHCVGVEQDEESEASDWQGFSKGEGSKETMSVYNLIYDMKKKRPLKRPRLGPPDIYPQEAKQKEDELTSSNVKQGFTLLPHMEEFGTARNYNVTANKVGSYFNAILARKEELMTLPDSGRKKQQINPKDNFWPVTARTKATLDTWFKDLAGTKPLVSLAKKAPSFNKKEEIFAILSENQVSMQRAAWFIKLSSAYTVAVSEAKIKKRQMPDPATEWTGTMIKFMRELIPKLHEHYYQGVLPEKLQSSSASSSTPTSSASSTSITNTVPTPLTSPASSMHSPGNLGSTPSSTLLAPPSPQDEHKLALKQWTYCMQLSKYMYEEGLLDKHEFLNWILDLLDKVRSQPTDDGLLKLFLPLALQYMSDFVQSERLSRRLAYLVCKKMGHMINSAVENRHLMSQETAAAATAGNVKTEPAEAQNTDASKNPENADAKENPNKTGAKSAPVNGVQSTNPYTFFSDYMNCAHHRDLILQWSAIIQVITIECPTALVWCGIGENRASSIFIGSPLDHLPISPSSLPMPPRFTQANEEIRKQLRVVEESIKIRSKHAEARWCTDKWQSRWGEHRAMAVAWLLDKRQTEVTSSNENEATNGNSDDKDSISSGAGINGSPVFQKILMNFLDNDAPVLEENGSPQNRSQFTNLVHLFSELIRHDVFSHDGYMCTLIARGDLTTKGISATQPHTNVIPPGPISNPTKTSPGMHPGLDEDVFAGIEFKSKIEEFDDSNVDDDLDKLLQHIKSDQQNSMDAPDSPKDPDNSTQGASHIGIGTDSTVSRHFLYTKHFPLSQDGDMASQHDCNQRYILLFGVGKERDEKKHAVKKMSKEICKLFSKKFSIDVAEGILKELPEVESQLISKNSILVRNYTTSLSLYVVGVLRRYHCCLLLSPEQTSAVFEGLCKVVKHVTNPGDCSSAERCILAYLFDLYSSCSLLKTKPQPTEPFHNAYPKIKQALYSAVQIQASTHPYNPQFMIEILTQPKRGGKIEAGWGRPLNDSAANRYSFVCNAILAVVRENDNDRLNDIAATCAELTACCNALSAEWLGALVALCGSSNDTFYPDIVCQVDVQNLSIHNALAVFTCILVARHCFSLENFVASVALPALVAICNGTGRDMTPEAEAGARLTCHLLLRLFKTIEIPQPGLYSVSTSPNPIISGPACNIKLSCDRHLLAAAHKNIAVGPVLAVLKGILVVGDAMAHKASSVHSSGKRSGLNTPVHPGSTPKSMGSAGDLSHILGTSEFGLLGNCDEPMLDSSQQNHSVHSENASSLYDFAQHVLRQICSQEWVLERCLQNAEELCLPGMLIDPMLTPKQAQRLLHMICYAENESNMKAEMDQKSIIVRILENLEQWSLRISWLDLQLMFKQTNSNSAELTNWLDTEKPSIWLVAPLVSKLPSQVQGRILRVAGQVLESTNIFGAKGRDSGNGGNNGGGSCSKRKATPQLSHQPFLGLVLTCLKGQDEQKEGLLTSLHTQLSQFLQSNKEMERIGGIEDPQGRESMLDALQLRFSLVGGMFDSIQKNAASTTDWAILLAQLISQGVIDLTNNSELFTTVVDMLATLIHSTLVSDSQSERDDTKKSYTNLMKKLRKELGDKNNASVKFVRQLLPLSKQTCEVIACDSASSLTDTKGNKISGFDSIDKKYGLRIADKQRVSVWDLLEGHKNPAPLSWAWFGAVKMERKPLAYEDSHRLLKYHTHSLTKPSSYFHEPLPLPPEDLEPLPEKPVSFGDASKQDTLLKMLSLQKEDMKADTPSSVDQSPSAMIGTNGRVKPKGRRPRKPKPGPANIPINQPQQPQPPPQQQQQQQQQQPMQTQMPN
Length1965
PositionKinase
OrganismLutzomyia longipalpis (Sand fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Psychodoidea> Psychodidae> Lutzomyia> Lutzomyia.
Aromaticity0.06
Grand average of hydropathy-0.410
Instability index49.16
Isoelectric point6.67
Molecular weight217780.27
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09131
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.88|      52|      54|    1355|    1408|       1
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 1355- 1408 (86.59/67.50)	SVHSSGKRSGLNTPVHpgSTPKSMGSAGDLSHIL.GTSEFGLLGNCDEPMLDSSQ
 1412- 1464 (89.28/61.96)	SVHSENASSLYDFAQH..VLRQICSQEWVLERCLqNAEELCLPGMLIDPMLTPKQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.56|      46|     449|     820|     868|       3
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  820-  865 (81.50/50.89)	CTL......IARGDLTT..KGISATQPHTNVIPPGPISNPTKTSPGMHPGLDED
  874-  927 (68.06/34.53)	SKIeefddsNVDDDLDKllQHIKSDQQNSMDAPDSPKDPDNSTQGASHIGIGTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     186.53|      58|     449|     594|     684|       4
---------------------------------------------------------------------------
   12-   75 (86.38/35.50)	ChPHHHDHHVHFdeSAIKE..NLEADNSIVYQKSGED.GVLVHLGfLQINHRYLLELQLPstVSPAF
  622-  682 (100.14/ 8.45)	C.AHHRDLILQW..SAIIQviTIECPTALVWCGIGENrASSIFIG.SPLDHLPISPSSLP..MPPRF
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     316.71|      99|     500|    1083|    1184|       5
---------------------------------------------------------------------------
 1083- 1184 (160.92/112.81)	SCSLLKTKPQPT.EPFHN.AYPKIKQALYSAVQIQASTHPYNPQFMiEILTQPKRGGKIEAGWGR.PLNDSAANRYSFVcNAILAVVRENDNDrLNDIAATCAEL
 1584- 1685 (155.79/96.08)	SCSKRKATPQLShQPFLGlVLTCLKGQDEQKEGLLTSLHTQLSQFL.QSNKEMERIGGIEDPQGReSMLDALQLRFSLV.GGMFDSIQKNAAS.TTDWAILLAQL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.38|      35|     858|      76|     111|       6
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   76-  111 (60.30/47.97)	LFGERIALSRDERCLPNVNC..KYIEFTGkVGGHYDLK
  935-  971 (60.08/42.68)	LYTKHFPLSQDGDMASQHDCnqRYILLFG.VGKERDEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.27|      18|      55|    1196|    1213|       9
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 1196- 1213 (33.36/21.71)	LGALVALCGSSNDTFYPD
 1253- 1270 (33.90/22.19)	LPALVAICNGTGRDMTPE
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.51|      37|     772|     722|     758|      10
---------------------------------------------------------------------------
  722-  758 (63.04/43.71)	EHRAMAVAWLLDKRQTEVTSSNENEATNGNSDDKDSI
 1499- 1535 (66.47/46.55)	EQWSLRISWLDLQLMFKQTNSNSAELTNWLDTEKPSI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.56|      28|    1356|     358|     388|      12
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  358-  388 (45.85/42.99)	VSEAKIKKrqmPDPATEWTGTM..............IKFMRELIP
 1716- 1757 (38.71/26.44)	VSDSQSER...DDTKKSYTNLMkklrkelgdknnasVKFVRQLLP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09131 with Med12 domain of Kingdom Metazoa
Unable to open file!