<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09124

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMDIETLTDIVFVVEGSAANGAYINELKTNYIVPTLENFSQGPIDDREYLVSDRHSTQYGIVFYRTAANLLETTCCTFGPFTSPQKVVEIFERLPLVGGGMESCANLAEGFATAHVCFEDMKETRAPFIEGSMALQKHCVLVCNSPPYSIPVTECWKFAGKTVEQLATLFHERKIYLSIIAPRKMPVLYKLYMKADGDQPLTAKNYAKNIRHLVLLKGYHLKERPQSPNGIMGTNQALQMSGTQQHPNAQQTGQNAGIVMDGNHASSQQQQQQQSAQVGGMNPNQQPGNPLSQQMLQQQQFSAQNSQNPMQNPNFQPQGNRWIFATNQQQTQNRPQFIGGSNSGVVASMVNAQSLAGQNPNSALISQLSAPPNQNINPMLQQQQQIRMQMLNQQQQLQQLQQGNMHSGSGTSNQIPTSAPNQANTSVPVQQHQPGTSSDQTVMREKIWSGTLEWVEKLKTDQPKITRSIQCTVTSSIKDGEPEIKAINWPPKMFMQLMPKQLVGNIGGGYFKESKTVVFKPQPCEASESLAKNMTQLFAGCVHFTTPTNMPTCDIKVLILLYTAEKNAFLGFIPNNQAMFVERLRKVIQQKQSMGMQQSAVTGNIQQQQQQQQIQNAMTAQVQNPLPSNVLNAQQQQQDTQQQQQQHYNQYATSQQQINMQIGGPIGPSPQLGAGDQVGTGNPIQQQQIAMMQHQRGAMMGTGPNNPQQQIPPQHALQQQQQRMVRPMMSNNPGLRHLLQQQSTPGQQFRPQMSAVGGQGVSIGPGMGPNQIGSGPGGSGGPNRPFEENFEMY
Length792
PositionUnknown
OrganismGlossina palpalis gambiensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.06
Grand average of hydropathy-0.616
Instability index51.91
Isoelectric point8.72
Molecular weight87478.93
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09124
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     717.44|     202|     335|     198|     421|       1
---------------------------------------------------------------------------
  201-  421 (326.02/114.87)	TA.KNYAKN.....................IRHLVLLkgYhLKERpqspNGIMG...TNQALQMSGTQQHpnAQQTGQNAGivMD.....GNhasSQQQQQQQSAQvGGMNPnQQPGNPLSQQMLQQQQFSAQNSQNPMQNPNFqpqGNRWIFATNQQQTQ........NRPQFIGGSNSGVVASMVNAQSLA.GQNPNSALISQLSAPPNQNINP..MLQQQQQ..IRMQMLNQ.......QQQL...QQLQ.QGNMHSG....SGTSNQIPTSAPNQ
  429-  520 (114.53/25.71)	...................................................................QQH............................................QPGTSSDQTVMREKIWSG...............TLEWV....EKLKT........DQPKITRSIQCTVTSSIKDGE..................PEIKAIN......WPPK..MFMQLM.........PKQL...V.....GNIGGGyfkeSKTVVFKP......
  524-  770 (276.89/73.12)	EAsESLAKNmtqlfagcvhfttptnmptcdIKVLILL..Y.TAEK....NAFLGfipNNQAMFVERLRK...VIQQKQSMG..MQqsavtGN...IQQQQQQQQIQ.NAMTA.Q.VQNPLPSNVLNAQQQQQDTQQQQQQHYNQ........YATSQQQINmqiggpigPSPQLGAGDQVGT.GNPIQQQQIAmMQHQRGAMMGTGPNNPQQQIPPqhALQQQQQrmVRPMMSNNpglrhllQQQStpgQQFRpQMSAVGG....QGVSIG.PGMGPNQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09124 with Med25 domain of Kingdom Metazoa
Unable to open file!