<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09115
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MAKMYGKGGKTAIESEEQQKLRWQVELEFVQCLANPNYLNFLAQRGYFKDQAFINYLKYLQYWKEPEYAKYLMYPMCLYFLDLLQYEHFRREIVNSQCCKFIDDQAILQWQHYTRKRIKMFNSVNNTQLNAATCGTEINEAQQPQMAAQQPGSNSAAGVNIQNGNTGVNTQQAQLVGSQQQSQQMNGTNSVNLGVGGPLMQKMQ |
Length | 204 |
Position | Middle |
Organism | Glossina palpalis gambiensis |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea>
Glossinidae> Glossina.
|
Aromaticity | 0.11 |
Grand average of hydropathy | -0.614 |
Instability index | 49.38 |
Isoelectric point | 8.53 |
Molecular weight | 23482.40 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP09115
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 90.07| 28| 29| 136| 164| 1
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136- 164 (45.78/22.51) TEINeAQQPQMAAQQPGSNSAAG...VNIQNG
166- 196 (44.29/18.48) TGVN.TQQAQLVGSQQQSQQMNGtnsVNLGVG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 95.03| 26| 38| 23| 49| 2
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23- 49 (46.15/28.25) WQvELEFVQCLANPNYLNF..LAQRGYFK
63- 90 (48.87/26.19) WK.EPEYAKYLMYPMCLYFldLLQYEHFR
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