<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09114

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMMNQLQMGGQHGGPGGMMSMGSMGYNQGGMMQQQQQGIGPGVMNPVGMQSPSHVQQQLMQQQQIQMQQQQQQMGPQMGMVNQPGLSPQVMLQQQQQQQQQLQQVQMHQNVNMQQSQQIQNSSGAAANMIMMAQQQTQQQQQQQQQQSQMQQQAQQAQTQQQMPQGSGSQGSQQPANNIMSISQQPHKEINIVALSRVGQETVQDITSRFQEIFTALKVIQPTANRDNSTVKKVQEHFRTIRLLFKRMRLIYERCNDGYPQGMEYTTVESLIPFKDEPEHRLGLEATQCEEYRKALQENQELIDTVKLKNRQLREIIDRTRIIVWEINTMLSMRKS
Length335
PositionHead
OrganismGlossina palpalis gambiensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.03
Grand average of hydropathy-0.897
Instability index66.43
Isoelectric point8.91
Molecular weight38355.14
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09114
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     225.58|      45|      45|      27|      71|       1
---------------------------------------------------------------------------
   27-   71 (91.03/20.01)	QGGMMQQQQ.QGIGPGVMNPVGMQSPSHVQQQLMQQQQIQMQQQQQ
   76-  108 (61.57/11.24)	QMGMV..NQ.PGLSPQVM....LQ......QQQQQQQQLQQVQMHQ
  109-  154 (72.97/14.64)	NVNMQQSQQiQNSSGAAANMIMMAQQQTQQQQQQQQQQSQMQQQAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.32|      26|      26|     220|     245|       2
---------------------------------------------------------------------------
  220-  245 (43.06/26.22)	QP......TANRDNSTVKKVQEH...FRTIRLL..FK
  248-  274 (35.89/20.80)	RL......IYERCNDGYPQGME....YTTVESLipFK
  276-  307 (17.37/ 6.80)	EPehrlglEATQCEEYRKALQENqelIDTVKL.....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09114 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MMNQLQMGGQHGGPGGMMSMGSMGYNQGGMMQQQQQGIGPGVMNPVGMQSPSHVQQQLMQQQQIQMQQQQQQMGPQMGMVNQPGLSPQVMLQQQ
2) QLQQVQMHQNVNMQQSQQIQNSSGAAANMIMMAQQQTQQQQQQQQQQSQMQQQAQQAQTQQQMPQGSGSQGSQQPANNIMSISQQP
1
100
94
185










Molecular Recognition Features






MoRF SequenceStartStop




NANANA