<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09075

Description Uncharacterized protein
SequenceMNNRQILDLTLRLSQALDQNYDVVNMDAVLSVITTLENTTVTKAHLETTRLAKYINQLRRRTKCEHLARRAKSLLKRWREMVGIQQAHQNEATLTTTLHVNNTPVISGLSMSNFGAEPSQPPSQATQMRFQSDSANYSLQSNQNYAQSQRPSQFYSQTERNLPNDLSYSRNIDVNSDFLRNTTSNSAPISSLTKSANPSSTKRLSRNSHEQKQQQPTSFANLLSGLNASSDSACGNSKGSSIKPHKTIAKRDTDTVQAVETLIIDHSSNSNSEIVFMPSNCTNCTKTANVPPIIIDLQDTNSVETNEHHLVVDPKVIGISSSSKSRKSRINKKRREATNSIEFDVASLDNDCVSKPFIGETKSCSVCPISSISEILSLSNSSMSSVFPMEKIMVNADCSVSKTNNQSQLADKVPKSDLTFAGKFKQASGQPTCDRVSEYKCNRDVIIDGVSSTASNNNHSSSPNVLDMKISPKTSTKFTHFGGVGINSNDSTSNSRISQFELGKAEKFPHVFYNTSQNNEDTSLQKQQCAYKHENYTASTYLKDSVVPILEMKQAVSRVCTTDEVKVPKKRGRKKGSKGIDSIIAKEVSLSSEMLISSLGTGVKKVKTTKELYAEIKSRKLVAEASEVAEVVISPSTSISSQLQSQQQAFSGPESSCSEPSLHSPRTLDACSTNATMSTVATRSTPDKSIAETHPDDSFTLTDDSILPSKMMLVTPRENHTQDANSNSCSDIKSESLGNACSVAVTTVNSISAIRAQICELTKKFVPVSLVKFTQDSLPCTCTIVEITPEKFRGVDKFKKVDEDSTDINQTNSNITVALEQFQMPVAAASDEFVASKLAQHDTNANSQLPSSLTSCLTPRQKHKKSIFDFDFDDNEEDPLHTIIADLAANKKSGTACSGDEERSNEACNKRSVVENEIGKQMVISRCTSHRQQPNQNDSSPTPHSKISIYQTQEDPNCKAKYRFEIETQQITGFHIKALHNTFIENVNGNWNHSCELKNVIVETDYLDKKKMVDGYDVVPRYGSLIKERILKDLTAVIFTSNYKRKRNSLLIEKLKNLPFLGVARTTLLGNSIQRNNMETRSTLSMLDEVKQQLEKREVSTFANYVGSADPVPKDDVNLFVNVSDSSKISPIRASDNISDQTTTAPLLVLAAPHLNRKYIESDDNSVSCLRRRRKSEGNASSDNETKLINEPKYYDKENTRCEQDKEGFWKSKYRKRKIMERRTLSKHECRRTIKRLKIAANGDIATHKQIALSNTNTNSTDEEEDLSEIDSHFINENSVVVESNDDEDDKMDSCVSENRNLAAYDEGSNECGGDFHEVIARSSNSTSIVLTIKKTPSKSKFRTNPYANSSQNFVNIGKNMYTQDRYIEPKGNSALKASSIKAEENRLQQEKTDCKLTSKFQRGDDIKTLAKQVSIKGSLEKKMGSSKENLHNQLFFSEELCPSISDDVIDFSSEGEVGSAHLENDKGGCYKKLAEAHEELSRIKLSCEFNTKQLQTSSPPSESGSSNTSIDVCHRDCDDNGNCDQRIDDDDLPLENNNLLSSFNNIYYFSSKEKLGHASNQETASPSLQHHNKLMIEQIPNAICDVYSVYTTNNHSGNYINLKGLVDNSACAKKNSLDPHDDINNDSGSDGSNIWDEEDRRLRQQVKSKTKEVDQSKFSVPYEEYRIGVRAFDKNTPQHGNCSRLQQFKEWHEVLQLHSYNDELLTVLPYVVLE
Length1715
PositionUnknown
OrganismGlossina pallidipes (Tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.05
Grand average of hydropathy-0.710
Instability index51.29
Isoelectric point6.52
Molecular weight190970.42
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09075
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     342.54|     114|     153|      11|     136|       1
---------------------------------------------------------------------------
   11-  136 (170.57/156.98)	LRLSQALDQNYDVV.NM...DAVLSVITTLENTTVTKahlettRLAKYINQlRRRTKCEHLARRAKSLLKRWREMVGIQQA.....HQNEATL.TTTLHVNNTPVISGLSMSNfgAEPSQPPSQATQMrfqSDSAN
  166-  289 (171.97/124.26)	LSYSRNIDVNSDFLrNTtsnSAPISSLTKSANPSSTK......RLSRNSHE.QKQQQPTSFANLLSGLNASSDSACGNSKGssikpHKTIAKRdTDTVQAVETLIIDHSSNSN..SEIVFMPSNCTNC...TKTAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.44|      23|      26|     842|     866|       2
---------------------------------------------------------------------------
  842-  866 (35.61/26.08)	DTNANSQLPssLTSCLTPRQKHKKS
  871-  893 (38.82/22.30)	DFDDNEEDP..LHTIIADLAANKKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.77|      32|     153|     293|     327|       3
---------------------------------------------------------------------------
  293-  327 (45.24/33.91)	IIIDlqDTNSVETNEHHlVVDPKVIGISSSSK.SRK
  445-  477 (50.52/27.73)	VIID..GVSSTASNNNH.SSSPNVLDMKISPKtSTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     145.03|      43|     153|     385|     429|       4
---------------------------------------------------------------------------
  385-  429 (71.41/50.47)	SVFPMEKimVNADCS.VSKTN.......NQSQLADKVP...KSDLT..FAG....KFKQASG
  739-  778 (37.33/18.74)	..........NA.CS.VAVTT.......VNSISAIRAQ...ICELTkkFVPvslvKFTQDSL
  794-  840 (36.29/18.56)	GVDKFKK..VDEDSTdINQTNsnitvalEQFQM....PvaaASDEF..VAS....KLAQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.32|      55|     414|    1110|    1169|       5
---------------------------------------------------------------------------
 1110- 1169 (84.86/76.71)	DPVPKDDVNLFVNVSDSSKISPIRASDNISDQTTTAPLLvlaaPHLNRKYIESDDNSVsC
 1531- 1585 (96.46/71.59)	DDLPLENNNLLSSFNNIYYFSSKEKLGHASNQETASPSL....QHHNKLMIEQIPNAI.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.81|      20|     414|     897|     939|       6
---------------------------------------------------------------------------
  671-  690 (34.65/ 7.35)	CSTNATMSTVA..TRSTPDKSI
  897-  918 (29.16/46.42)	CSGDEERSNEAcnKRSVVENEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.74|      25|     833|     330|     356|       8
---------------------------------------------------------------------------
  330-  354 (40.85/27.72)	INKKRREATNSIE..FDVASLDNDCVS
  358-  384 (36.89/17.36)	IGETKSCSVCPISsiSEILSLSNSSMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.84|      15|      15|    1295|    1309|      10
---------------------------------------------------------------------------
 1295- 1309 (25.42/18.02)	CVSENRNLAAYDEGS
 1312- 1326 (26.43/19.09)	CGGDFHEVIARSSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     198.40|      61|     161|    1450|    1526|      11
---------------------------------------------------------------------------
 1462- 1526 (99.75/66.20)	H..LENDKGGCYKKLAEahEELSRIKLSCEFNTKQLQTS..SPPSEsgSSNTSIDVCHRDCDDNGNCDQ
 1621- 1685 (98.65/40.56)	HddINNDSGSDGSNIWD..EEDRRLRQQVKSKTKEVDQSkfSVPYE..EYRIGVRAFDKNTPQHGNCSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     241.48|      79|     161|    1181|    1286|      12
---------------------------------------------------------------------------
  926- 1013 (117.15/52.42)	RCtshRQQPNQNDSSPTPHSKISIYQTQEDPNCKAKY.RFEIETQQITGFHIK.ALHNTfieNVNGNwNHSCELKNviVETDYLDKKKMV
 1201- 1281 (124.33/101.43)	RC...EQDKEGFWKSKYRKRKIMERRTLSKHECRRTIkRLKIAANGDIATHKQiALSNT...NTNST.DEEEDLSE..IDSHFINENSVV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09075 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HKQIALSNTNTNSTDEEEDLSEIDSHFINENSVVVESNDDEDDKMDSCVSENR
2) KNSLDPHDDINNDSGSDGSNIWDEEDRRLRQQVKSKT
3) SGLSMSNFGAEPSQPPSQATQMRFQSDSANYSLQSNQNYAQSQRPSQFYSQTERNLPNDLSYSRNIDVNSDFLRNTTSNSAPISSLTKSANPSSTKRLSRNSHEQKQQQPTSFANL
4) SVSCLRRRRKSEGNASSDNETKLINEPKYYDK
1248
1615
107
1166
1300
1651
222
1197










Molecular Recognition Features






MoRF SequenceStartStop




1) NNIYYF
1545
1550