<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09063

Description Uncharacterized protein
SequenceMDYDFKMKTQKERTKVEDLFNYEGCKVGRGTYGHVYKAKWKETSDGKEYALKQIDGTGLSMSACREIALLRELKHQNVITLIRVFLSHTDRKVFLLIDYAEHDLWHIIKFHRAAKAAKKQVVVPRGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGDGPERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHHTLTKDFKRSSYSTCSLAKYMDRHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFQEEPLPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQQQQQQQQQQQQQHHEPNAKRVRLSGPGGAPQQQQQVHPQQQQDFHHQQQQQAAAAAAVVAQQQQQQQAAAAQQMMFNQQQQNFQQRF
Length472
PositionKinase
OrganismGlossina pallidipes (Tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.09
Grand average of hydropathy-0.820
Instability index54.86
Isoelectric point8.86
Molecular weight55112.94
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09063
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.72|      15|      15|     370|     384|       1
---------------------------------------------------------------------------
  370-  384 (32.86/11.12)	NKRQQQQQ.........QQQQQQQ
  386-  400 (29.64/ 9.43)	QQQQQQQQ.........QQQQHHE
  429-  452 (25.22/ 7.10)	FHHQQQQQaaaaaavvaQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.37|      13|      40|     215|     254|       2
---------------------------------------------------------------------------
  215-  249 ( 8.42/56.49)	IDiWaigcifaelltsepifhcrqEDIKtSNPYHH
  265-  277 (28.95/10.92)	KD.W....................EDIK.KMPEHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.66|      25|      38|     102|     138|       3
---------------------------------------------------------------------------
  102-  129 (41.55/44.44)	HDLWhiiKFHRAAKAAKKQVV..VP.RGMVK
  143-  170 (39.11/16.82)	HSNW...VLHRDLKPANILVMgdGPeRGRVK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09063 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNKRITSEQAMQDPYFQEEPLPTQDVFAGCPIPYPKREFLTDDDQEDKSDNKRQQQQQQQQQQQQQQQQQQQQQQQQQHHEPNAKRVRLSGPGGAPQQQQQVHPQQQQDFHHQQQQQAAAAAAVVAQQQQQQQAAAAQQMMFNQQQQNFQQRF
320
472










Molecular Recognition Features






MoRF SequenceStartStop




1) QQQQQHHEPNAKRVRLSGP
393
411