<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09028

Description Uncharacterized protein
SequenceMLSLLQEKRPLKRSRLGPPDVYPQEAKQREDELTPSNVNKGFASMPPLSDEFGTAHTSNVNASKVASFFNAILAKKEELMTLQDTVRKKQQINFKDNFWPVSPRTKGALDAWFKDLAGNKPLLSLAKKAPSFNKKEEILITLCDHQVNMQRATWFIKLSAAYMVSVSESKNKKRNSFDPVPEWTGNLIKFMKELLPKLQEYYHLCEKSSSSEKASLSGQGAPTTQNNNASLALSHSSNNATLVPSIASPVPMLSPANSQSSSSGGLGVLSSNSGSGVGTSSSQSSITGANQTPVSGSSISGIGSNFEDSRNALKYWNYCTQLSKYMHEESLLDRMEFLNWILELLDRMRTQANFDESLKRLVLTFALPYMQDFVQSERLCRKMAYIVAKKLTNLLNAVIDQQQPLTNGKSENTTHMEMDEEIDKKKTQLDPYEVAINEYLNCPHHRDIILYLSTILQVITVECPTAMVWCGIGENRAPAALCGSPLDHLPVAPSILPMPIKCPITNAEVRRQLRATEAEIVLRSKHAENRWFAEKWQNANKNSYTHVLSILDYLDTHCFDRMDQTNSIDSLYANIFKTFVTIRREVGPNGEIKEIRHEYDANVVDGNTVRILCEWAVSSQRWGEHRAIVVALLLDKRQIEVTTPNEPDNNIGNAVAHSNNNLNDDKDSIASGAGLIGGLPVFQSVLMNFLDHDAPVLDENGGMTNRTQFTNLVHLFSALIRYDVFSHNAYMHTLISRGDLLEGVANVDSSKPSVTATTTVSGPVSNKASSPPVNQGFDDDFGTSMDFKHNEFDDSNVDDDLDKLLQNIKEKGQAEAPDSPKIPDTSNSIGCDNANSSISRHYIYTKHFPIPQDDPTTSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEICKLFTKKFSIDVAEGGKVKKHSRNEFNFEATTSKCQNMAYFDQHVVTSQCAATVLEQLNAFALGSNNYLPVQEHVAFLFDLMEMALNIHSLLELCDQILKELPELENQLQAKKSNMVRSYTTSLGLYIVGILRRYHSCLLLSPEQTVSVFDGLCRTIKHVTNPSECSSAERCILAYLSDLYESCFLLKTKEQEPEFFQQMAAIKKFKDIFNAPEQLGIVPQAYNPQFLQELFTSPKRGGKIDSIWLHQLHESPSNVYSFVSNAIVAVCHEADNDRLNDIAISCAELTAGCNALSEEWIAALQSICNAMKKPRYPHFCQVDIQNSKIHNSLAVFICILVARHCFSLADFVMNFALPTLANAYPVGGEISADAEAGARLTCHLVLKLFKTIEIPQPGMYSVSTSPNPLTTVGSSSNIKLSCDRHLLIGAHKNVPLEAVLAVLKAILIVVDTTALKTSNMSGNSSGGAFGTTGGKRSGFSTPVHPGSTPKSNERPVDLSQILGTSDLNSLNTEHDHDMTQQLTSTPSNTGALNNSEQISLLEFAQHVLKQICAQEHVLERCLKNAEKLCDMIIDEMLTPKQVQRILHMICYPESEYNIISELDQRSMIVRILENLGQWTLRISWLDLQLMHRQSMNNPAELSSWLDTVARAAIDVFLMEEVVVASGLKSEHRPKASTWLVAPLVAKLTPAVQGRILRVAGQVLESMSYFSKVSKSDNNSSCSGDEREKSNSCGSASSSYSIGVNGSNSRSRKMPLNYQPFLGLILTCLKSQDEYKEGLLCSLYSQLSQCLQSYTEFDTMGGVDDPLGREEMLDALQLRFSLVGGMFESIQKNGTSITDWAILLAQLVCQGVVDLSTNKELFTTVVDMLTTLVHSTLVSDGQSERDEKFYSNLMKKLKKEIGEKNNASIKVIRQLLPLYKQPTEVISCEPAGVDQKGNKINDMDKKQLRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSLVKPSSYYYEALPLPPEDIEPIAEKIVTPTLFLQKDEMKADTPSSVDQSPSAVVNMQQFNSNQMMQQNPNAIIQQQQQMPGVPSGIQQQMNVGNSQQSSQMVNRFERPPHMSNSRQAIHNMLRHRQPPMNQNNSAAFNTMQQQQRQTQGLTTQSQTGVLNPVQQQQLQQQQFARSGMRSMAPSQLTGAAPNQMAPGINTVGMGSQTLGTQNPIMQQQISAQTMNPQNNNQMIMNQNAGVMSTGNNQNANIMTSQNSTGLVSASAMMQQNVGVGGGAVGQNMVNQNAGQFQNFSQYQHQTINQSGNSNQQANIVANFMAQQQQQQPPQRGPAGMTSNRGQYMSQAPNVTMNSTMGQGAVPPYSRQQTSGGKPGVVSTQQQFQQQQRLQHQMMQMQGIGPQNNGASGMTQPQNQSVGQQQTPNLVAHLQQRSMLNQPNMMGQQYQHQPPPY
Length2337
PositionKinase
OrganismGlossina fuscipes fuscipes (Riverine tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.06
Grand average of hydropathy-0.423
Instability index48.12
Isoelectric point6.48
Molecular weight259477.06
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09028
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     124.90|      32|     625|    1398|    1433|       1
---------------------------------------------------------------------------
 1936- 1971 (38.56/13.89)	QSPSAVVNM........QQFNSNQMmQqnpnaiiQQQQQMPG...........V..P
 2096- 2141 (12.93/ 6.38)	....GTQNPIMQqqisaQTMNPQNNnQ.......MIMNQNAGvmstgnnqnanIMtS
 2188- 2216 (30.78/ 9.45)	INQSG..NSNQQ.anivANFMAQQQ.Q.......QQPPQR.................
 2257- 2286 (42.63/16.10)	.GKPGVVST..Q.....QQFQQQQRlQ.......HQMMQMQG...........IG.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.87|      35|     625|    1398|    1433|       2
---------------------------------------------------------------------------
 1398- 1433 (58.40/40.27)	LNT.EHDHDMTQQLTsTPSNTGALNNSEQISL..LEFAQ
 2025- 2062 (54.48/32.74)	FNTmQQQQRQTQGLT.TQSQTGVLNPVQQQQLqqQQFAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.68|      19|      44|    1026|    1044|       3
---------------------------------------------------------------------------
 1026- 1044 (35.23/21.98)	YHSCLLL.SPEQTVSVFDGL
 1072- 1091 (32.45/19.63)	YESCFLLkTKEQEPEFFQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.77|      18|      87|    2229|    2249|       4
---------------------------------------------------------------------------
 1999- 2016 (30.26/14.07)	MSNSRQ..AIHNMLRHRQPP
 2229- 2248 (30.33/15.13)	MSQAPNvtMNSTMGQGAVPP
 2319- 2336 (36.18/13.68)	MLNQPN..MMGQQYQHQPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.46|      18|      23|    1470|    1491|       6
---------------------------------------------------------------------------
 1470- 1491 (25.32/27.71)	VQRILHMIcypeSEYNI.ISELD
 1496- 1514 (26.15/14.89)	IVRILENL....GQWTLrISWLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     248.85|      67|     469|     262|     359|       8
---------------------------------------------------------------------------
  262-  329 (114.94/57.88)	SSGGL..GVLSSNSG.SGVGTSSSQSSITG.....ANQTPVSGSSIS.GI.GSNFEDSRNALKYWNYCTQLSkYMHEE
  736-  791 (79.24/31.59)	SRGDLleGV..ANVD.SSKPSVTATTTVSG.........PVSNKASSpPV.NQGFDD........DFGTSMD.FKHNE
 1590- 1648 (54.67/18.37)	........VLESMSYfSKVSKSDNNSSCSGderekSNSCGSASSSYSiGVnGSNSRSRKMPLNYQPF...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.27|      46|     470|     803|     851|      10
---------------------------------------------------------------------------
  803-  851 (74.62/54.34)	KLLQNIK..EKGQAEAPDSPKiPDTsnSIG.CDNANSSISRHYIYTKHFPIP
 1275- 1323 (72.65/42.90)	KLFKTIEipQPGMYSVSTSPN.PLT..TVGsSSNIKLSCDRHLLIGAHKNVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.35|      63|     470|     417|     491|      12
---------------------------------------------------------------------------
  417-  491 (91.84/99.23)	EMDEEIDK...KKTQLDpyevaINEYLNCPHH.RDIILYLSTILQ..........VITVECPTAMVwcgigENRAPAALcGSPlDHLPV
  886-  962 (90.50/61.07)	KMSKEICKlftKKFSID.....VAEGGKVKKHsRNEFNFEATTSKcqnmayfdqhVVTSQCAATVL.....EQLNAFAL.GSN.NYLPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.90|      11|     465|     142|     154|      14
---------------------------------------------------------------------------
  142-  154 (19.89/19.37)	LCDHQVNMQRatW
  612-  622 (24.02/15.51)	LCEWAVSSQR..W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.41|      12|     465|     984|     995|      15
---------------------------------------------------------------------------
  984-  995 (22.34/12.02)	ELCDQILKEL..PE
 1455- 1468 (19.07/ 9.27)	KLCDMIIDEMltPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.47|      20|     128|    1689|    1708|      17
---------------------------------------------------------------------------
 1689- 1708 (35.29/22.51)	GVDDPLGREEMLDALQLRFS
 1819- 1838 (35.18/22.41)	GVDQKGNKINDMDKKQLRIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09028 with Med12 domain of Kingdom Metazoa
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