<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP09012

Description Uncharacterized protein
SequenceMNNRQILDLTLRLSQALDQNYDVVNMDAVLSVITTLESTTVTKAHLETTRLAKYINQLRRRTKCEHLARRAKSLLKRWREMVGIQQAHQNEAALTTTLHVNNTSLISGLSISNLGTDSPQLPPHATQMRFQSDSINYTLQSNQTHAQPQRQLQFHPQTELNFPNDLNYSRNTDTNNEFLRNTTSNSAPVSLLTKSVNPTNVKRLNRNAHEQKHQQQQPISFANLLSGLNTSSDSICGNSKSSSMKTHKRIAEHDSVQTVETLIIDHSSNSNSEIVFMPSNCTSCIKTENVPPIIIDLQDTNSVETNEQHLVVHPKVISISSSSKSRKSRINKKRRDATNSIEFDVASLDNDCVDKSALSGETKSCSVCPISSISEILSLSNSSMSSVFPMEKVMVNANSSVSTTNNRSQVGDKVPKSDLTFAGKFKQASAQSACDRVLEYKCNRDVIIDGVGSNASNNNQSYSPNILDTKTSPIISNKFTPFSGVGINSNDSTSNSRISQFEAVKGEKFSHVFYNSSPKHNEDTSPQKQHCAYKHESYSTSTYLKDSVVPISETKQADPGICNTGEVKVPKKRGRKKGSKGVDSVIAKEVSLSSEMLISSLGTGVKKVKTTKELYAEIKSRKLVAGAAEPAERVASPATSINSQLQTQQQAFSGPESSCSEPSLHSPRTLDACSTNATMSTVATRSTPDKSVAETHPDDSFTLTDDSILPSKMVAVISREHNTQDTNSNTCSDIKSESFENARNVPLTTAASISAIRAQICELAKKFTPVSSLKFTEDNIPCTCTVVEVTPEKFKGIDKINEADEGLIDVNQTNSNITVALEQLHSSTAATADEISKPKTVEHEVTDITINSQVSRSPLSCLTSKQKLKKSIFDFDFDDNEEDPLHTIIADLAANKKNETAYSGDEERSNEASKIRSVVEKEIEKEMVISRCTSQKQQQYQHDATPALVPEMPIYQTQEDPNCRAKYRFEVETQQITRFHIKALHNLFIENVNGNWNHACDGKKVIGEIDYLHKMKIEDGYDVVPRYGSLIKERIAKDLTTVLFTNNYQRERNSLLIIQKLKNLPFLGVARTTLLEKLTQENKSVTRSTLVVNEEKQQLEKHKESTFTNYLTNADHAAQRNVNLFVNVSESITKTSPTPSSNNNNVNGQGTTAPVLFIAERKQIENEDNSVSCLRRRRRSRDNIFNNAETKLINQPECYDKENSHCKEDKEDVWKRKYTKRKIKERRMLSKHGCPHSIKRLKISVNGDIATHKQITLNNSNNNSTDEEGNQSEIDEIENEGTAMDDNQFVNENSVAPAGNDEEAGEDKMDKDIADNRDLVENDERDNEYFGDFHEVIPRSSSSTSIVLTIKKTPSKSNFHTKICANTSQNIINVKKNAYTQDKYIALKRNSILETSPDGAEEDQVKKEKKICRLTSNLQGVSDIKMQENQVSKKKFLQKIKDFSKGNLHNQLFFSEELHPSISEDVFNFSSGEEACAMDLESEEGDCYHELTEAHQGVGRIKPSDELNTTQFETSSPSSGSEYLSGNSNASVNDSQHDHGDNENDSQHIDDDGLPLENNNLLLSFNNIYYFSSQEKQKHESSQEILSPSMQHRNKLILGQIPNEICDVYSVYTTNNHSGNIFNLKELVDSSAERNFLDSNDDIHNDSGNGGTNTCVEDENQLRQQAKLKIKMDDHSKFAVPYEEYRTGVRAIDEDIPEQGYCSRLQQFKEWHEVLQLRSYNDELLTVLPYVVLE
Length1734
PositionUnknown
OrganismGlossina brevipalpis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.05
Grand average of hydropathy-0.747
Instability index49.88
Isoelectric point5.86
Molecular weight194015.02
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP09012
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      88.26|      18|     130|     225|     242|       1
---------------------------------------------------------------------------
  225-  242 (32.95/13.49)	LSGLNTSSDSICG......NSKSS
  358-  374 (31.26/12.48)	LSG.ETKSCSVCP......ISSIS
  377-  400 (24.05/ 8.19)	LSLSNSSMSSVFPmekvmvNANSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     434.37|     148|     668|     743|     914|       3
---------------------------------------------------------------------------
  483-  528 (23.07/12.69)	SGVGINSNDSTSNSRI......SQFEAVKGEKFSHvfyNSSPKHNE..DTSPQK..............................................................................................................................
  743-  896 (224.17/123.46)	RNVPLTTAASISAIRAQICELAKKFTPVSSLKFTE...DNIPCTCTVvEVTPEKFKGIDKINEADEgLIDVNQTNSNITVALEQLHSSTAATA.DEISKPKTVEHEVTD..................ITINSQVSRSPLSCLTSKQKLKKSifDFDFDDNEEDPLHtiIAD....LAANK
 1410- 1560 (187.14/89.67)	................KICRLTSNLQGVSDIKMQE...NQVSKKKFL.....QKIKDFSKGNLHNQ.LFFSEELHPSISEDVFNFSSGEEACAmDLESEEGDCYHELTEahqgvgrikpsdelnttqFETSSPSSGSEYLSGNSNASVNDS..QHDHGDNENDSQH..IDDdglpLENNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.00|      20|     431|     277|     302|       4
---------------------------------------------------------------------------
  277-  302 (32.22/34.82)	MPSNCTSCIKTENvppiiiDLQDTNS
  709-  728 (35.79/22.46)	LPSKMVAVISREH......NTQDTNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.83|      24|     432|     908|     960|       5
---------------------------------------------------------------------------
  632-  656 (37.94/ 6.07)	ERVASPATSiNSQLQTQQQAFSG..PE
  926-  951 (41.89/55.79)	EMVISRCTS.QKQQQYQHDATPAlvPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.81|      13|     486|     104|     116|       7
---------------------------------------------------------------------------
  104-  116 (22.91/13.56)	SLISGLSISNLGT
  591-  603 (22.90/13.55)	SLSSEMLISSLGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.27|      28|     445|    1206|    1236|      11
---------------------------------------------------------------------------
 1206- 1236 (43.69/56.40)	CKEDKEDVwkRKYTKRKIKERRMlSKHGCPH
 1655- 1682 (50.58/46.11)	CVEDENQL..RQQAKLKIKMDDH.SKFAVPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.29|      14|      15|    1001|    1014|      17
---------------------------------------------------------------------------
 1001- 1014 (24.78/20.88)	DGKKVIGEIDYLHK
 1019- 1032 (25.51/21.78)	DGYDVVPRYGSLIK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP09012 with Med26 domain of Kingdom Metazoa
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