<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08985

Description Uncharacterized protein
SequenceMNNRQILDLTLRLSQALDQNYDVVNMDAVLSVITTLENTTVTKAHLETTRLAKYINQLRRRTKCEHLARRAKSLLKRWREMVGIQQAHQNEATLTTTLHVNNTPLISGLSMSNFGAEPSQAPSQATQMRFQSDSANYSLQSNQNYAQSQRPSQFHSQTERNLPNDLSYSRNIDVNSDFLRNTTSNSAPMSSLTKSANPSSTKRLSRNAHEQKQQQPTSFANLLSGLNASSDSACGNSKGSSVKPHKTIAKRDTDTVQAVETLIIDHSSNSNSEIVFMPSNCTNCTKTANVPPIIIDLQDTNSVETNEHHLVVDPKVISISSSSKSRKSRINKKRREATNSIEFDVASLDNDCVGKPFIGETKSCSVCPISSISEILSLSNSSMSSVFPMEKIMVNANCSVSKTNNQSQLADKVPKSDLTFAGKFKQASGQPTCDRVAEYKCNRDIIIDGVSSTASNNNHSSSPNALDMKISPKTSTKFAHFGGVGINSNDSTSNSRISQFELGKAEKFPHVFYNTSQNNEDTSLQKQQCAYKHENYTTSTYLKDSIVPILEMKQTVTRVCTTDEVKVPKKRGRKKGSKGIDSIIAKEVSLSSEMLISSLGTGVKKVKTTKELYAEIKSRKLVGEASQVAEVVISPSTSISSQLQSQQQAFSGPESSCSEPSLHSPRTLDACSTNATMSTVATRSTPDKSIAETHPDDSFTLTDDSILPSKMVPVTPRENHTQDANSNSCSDIKSESLENSCSVAVTTVNSISAIRAQICELTKKFVPVSLVKFTQDSLPCTCTIVEITPEKFRGVDKFKKFDEDSIDINQTNSNITVALEQFQMPVTAAGDEFVASKLVQHNINTNSQLSSSLTSCLTPRQKHKKSIFDFDFDDNEEDPLHTIIADLAANKKSGTACSGDEERSNEACNKRSVVENEIGKQMAISRCTSQRQQPNQNDSSPTPHPKIPIYQTQEDPKCRAKYRFEIETQQITGFHIKALHNTFIENVNGNWNHSCEPKNVIVEADYLDKKKMVDGYDVVPRYGSLIKERILKDLTAVIFTSNYKRKRNSLLIEKLKNLPFLGVARTTLLGNSIQRNNMETRSTLSILDEEKQQLEKREVSTFANYIGSADPVPKEEVSLFVNVSDSSKISPIRADDNVSDQTTTAPLLVLAAPHLNRKHIESDDNSVSCLRRRRKSEGNASSDNGTKLINEPKYYDKENTRSAQDKEGFWKSKYRKRKIMERRTLSKHECRRTIKRLKIAANGDIATHKQIALSTTNTNSTDEEEDLYEIDSHFINENSVVVENNDDEDEDDKMDNCISENRNLAAYDEGSNECGGDLHEVIARSSNSTSIVLTIKKTPTKSKLRTNPYANSSQNFVNVGKNMYTQDRYKEPKGKSALKASSIKAEENHLQQEKIDCKLPSKFQRGDDIKTLAKQVSIKASLEKKMGSSKENLHNQLFFSEELCPSISDDVIDFSSEGEVGSTHLENEKGGCYKKLAEAHEELSRIKLSCEFNIKQLQTSPPPSESEYLTGSSNTSINVCHHDCDDNGNCDQRIDGDDLPLENNNLLSSFNNIYYFSSQEKLGHASNQETASPSLQHHNKLMIEQIPNAICDVYSVYTTNNQSGNYINLKGLVDNSACAKKNFLDPPDDINNDSGSGGSNTWDEDDRQLRQQVKSKTKEVDQSKFSVPYEEYRIGVRAFDKDTPQHGNCNRLQQFKEWHEVLQLHSYNDELLTVLPYVVLE
Length1721
PositionUnknown
OrganismGlossina austeni (Savannah tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.05
Grand average of hydropathy-0.718
Instability index51.13
Isoelectric point6.53
Molecular weight191700.37
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08985
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.87|      14|      28|     897|     912|       1
---------------------------------------------------------------------------
  897-  912 (19.86/16.77)	CSGDEERSNEacNKRS
  927-  940 (26.01/13.95)	CTSQRQQPNQ..NDSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.76|      17|      28|     758|     785|       2
---------------------------------------------------------------------------
  417-  433 (33.17/11.89)	DLT..FAG....KFKQASGQPTC
  760-  782 (24.59/35.40)	ELTkkFVPvslvKFTQDSLPCTC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.46|      22|      28|     456|     481|       3
---------------------------------------------------------------------------
  456-  481 (31.63/30.10)	NNNHSSSpNAldmKISP...KTSTKFAH.F
  487-  512 (31.83/16.32)	NSNDSTS.NS...RISQfelGKAEKFPHvF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.12|      13|      28|     112|     124|       4
---------------------------------------------------------------------------
  112-  124 (24.97/14.05)	SNFGAEPSQAPSQ
  141-  153 (25.16/14.22)	SNQNYAQSQRPSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.35|      24|      28|     692|     715|       6
---------------------------------------------------------------------------
  692-  715 (43.97/24.19)	ETHPDD..SFTLTD...DSILPSKMVPVT
  718-  746 (33.38/16.54)	ENHTQDanSNSCSDiksESLENSCSVAVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     203.25|      68|     833|     283|     362|       8
---------------------------------------------------------------------------
  283-  362 (96.01/85.66)	NCTKTANVPPIIIDlqDTNSVETNEHHLVV..DPKV..ISISSSSKSrKSRINKKRREATNsiefdvASLDNdcvGKPFIGETK
 1122- 1193 (107.24/64.01)	NVSDSSKISPIRAD..DNVSDQTTTAPLLVlaAPHLnrKHIESDDNS.VSCLRRRRKSEGN......ASSDN...GTKLINEPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     222.93|      74|     834|     514|     594|       9
---------------------------------------------------------------------------
  514-  594 (105.35/74.31)	NTSQN..NEDTSLQKQQcAYKHENYTTStyLKDSIVPILEMKQTVTRVcttdEVKVPKKRGRKKGSKGIDSIIAKEVSLSSEM
 1351- 1426 (117.58/63.18)	NSSQNfvNVGKNMYTQD.RYKEPKGKSA..LKASSIKAEENHLQQEKI....DCKLPSKFQRGDDIKTLAKQVSIKASLEKKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.14|      25|     698|     382|     415|      11
---------------------------------------------------------------------------
  364-  380 (20.68/13.33)	.........C...SVCPISSISEIL.SLSN
  389-  415 (35.30/21.81)	MEKImVNANC...SVSKTNNQSQLAdKVPK
 1583- 1603 (23.16/ 6.58)	IEQI.PNAICdvySVYTTNNQS........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.34|      18|      32|     807|     825|      12
---------------------------------------------------------------------------
  807-  825 (27.70/22.35)	DINqTNSNITVALEQFQMP
  842-  859 (31.64/20.27)	NIN.TNSQLSSSLTSCLTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.72|      10|      23|    1024|    1034|      13
---------------------------------------------------------------------------
 1024- 1034 (12.35/12.95)	SLIKERiLKDL
 1049- 1058 (16.37/10.67)	SLLIEK.LKNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.09|      15|      32|     623|     637|      16
---------------------------------------------------------------------------
  623-  637 (24.92/16.44)	GEASQVAEVVI.SPST
  652-  667 (24.17/15.67)	GPESSCSEPSLhSPRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.56|      39|     243|    1194|    1254|      17
---------------------------------------------------------------------------
   37-   79 (58.64/25.48)	ENTTVTKAHlETTRLAKYINQ..LRRRTKCEHLARRAkslLKRWR
 1198- 1238 (64.91/59.18)	ENTRSAQDK.EGFWKSKYRKRkiMERRTLSKHECRRT...IKRLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.99|      20|     672|     670|     689|      18
---------------------------------------------------------------------------
  670-  689 (35.16/21.11)	ACSTNATMSTVATRSTPDKS
 1323- 1342 (32.82/19.19)	ARSSNSTSIVLTIKKTPTKS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08985 with Med26 domain of Kingdom Metazoa
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