<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08985

Description Uncharacterized protein
SequenceMNNRQILDLTLRLSQALDQNYDVVNMDAVLSVITTLENTTVTKAHLETTRLAKYINQLRRRTKCEHLARRAKSLLKRWREMVGIQQAHQNEATLTTTLHVNNTPLISGLSMSNFGAEPSQAPSQATQMRFQSDSANYSLQSNQNYAQSQRPSQFHSQTERNLPNDLSYSRNIDVNSDFLRNTTSNSAPMSSLTKSANPSSTKRLSRNAHEQKQQQPTSFANLLSGLNASSDSACGNSKGSSVKPHKTIAKRDTDTVQAVETLIIDHSSNSNSEIVFMPSNCTNCTKTANVPPIIIDLQDTNSVETNEHHLVVDPKVISISSSSKSRKSRINKKRREATNSIEFDVASLDNDCVGKPFIGETKSCSVCPISSISEILSLSNSSMSSVFPMEKIMVNANCSVSKTNNQSQLADKVPKSDLTFAGKFKQASGQPTCDRVAEYKCNRDIIIDGVSSTASNNNHSSSPNALDMKISPKTSTKFAHFGGVGINSNDSTSNSRISQFELGKAEKFPHVFYNTSQNNEDTSLQKQQCAYKHENYTTSTYLKDSIVPILEMKQTVTRVCTTDEVKVPKKRGRKKGSKGIDSIIAKEVSLSSEMLISSLGTGVKKVKTTKELYAEIKSRKLVGEASQVAEVVISPSTSISSQLQSQQQAFSGPESSCSEPSLHSPRTLDACSTNATMSTVATRSTPDKSIAETHPDDSFTLTDDSILPSKMVPVTPRENHTQDANSNSCSDIKSESLENSCSVAVTTVNSISAIRAQICELTKKFVPVSLVKFTQDSLPCTCTIVEITPEKFRGVDKFKKFDEDSIDINQTNSNITVALEQFQMPVTAAGDEFVASKLVQHNINTNSQLSSSLTSCLTPRQKHKKSIFDFDFDDNEEDPLHTIIADLAANKKSGTACSGDEERSNEACNKRSVVENEIGKQMAISRCTSQRQQPNQNDSSPTPHPKIPIYQTQEDPKCRAKYRFEIETQQITGFHIKALHNTFIENVNGNWNHSCEPKNVIVEADYLDKKKMVDGYDVVPRYGSLIKERILKDLTAVIFTSNYKRKRNSLLIEKLKNLPFLGVARTTLLGNSIQRNNMETRSTLSILDEEKQQLEKREVSTFANYIGSADPVPKEEVSLFVNVSDSSKISPIRADDNVSDQTTTAPLLVLAAPHLNRKHIESDDNSVSCLRRRRKSEGNASSDNGTKLINEPKYYDKENTRSAQDKEGFWKSKYRKRKIMERRTLSKHECRRTIKRLKIAANGDIATHKQIALSTTNTNSTDEEEDLYEIDSHFINENSVVVENNDDEDEDDKMDNCISENRNLAAYDEGSNECGGDLHEVIARSSNSTSIVLTIKKTPTKSKLRTNPYANSSQNFVNVGKNMYTQDRYKEPKGKSALKASSIKAEENHLQQEKIDCKLPSKFQRGDDIKTLAKQVSIKASLEKKMGSSKENLHNQLFFSEELCPSISDDVIDFSSEGEVGSTHLENEKGGCYKKLAEAHEELSRIKLSCEFNIKQLQTSPPPSESEYLTGSSNTSINVCHHDCDDNGNCDQRIDGDDLPLENNNLLSSFNNIYYFSSQEKLGHASNQETASPSLQHHNKLMIEQIPNAICDVYSVYTTNNQSGNYINLKGLVDNSACAKKNFLDPPDDINNDSGSGGSNTWDEDDRQLRQQVKSKTKEVDQSKFSVPYEEYRIGVRAFDKDTPQHGNCNRLQQFKEWHEVLQLHSYNDELLTVLPYVVLE
Length1721
PositionUnknown
OrganismGlossina austeni (Savannah tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.05
Grand average of hydropathy-0.718
Instability index51.13
Isoelectric point6.53
Molecular weight191700.37
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08985
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.87|      14|      28|     897|     912|       1
---------------------------------------------------------------------------
  897-  912 (19.86/16.77)	CSGDEERSNEacNKRS
  927-  940 (26.01/13.95)	CTSQRQQPNQ..NDSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.76|      17|      28|     758|     785|       2
---------------------------------------------------------------------------
  417-  433 (33.17/11.89)	DLT..FAG....KFKQASGQPTC
  760-  782 (24.59/35.40)	ELTkkFVPvslvKFTQDSLPCTC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.46|      22|      28|     456|     481|       3
---------------------------------------------------------------------------
  456-  481 (31.63/30.10)	NNNHSSSpNAldmKISP...KTSTKFAH.F
  487-  512 (31.83/16.32)	NSNDSTS.NS...RISQfelGKAEKFPHvF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.12|      13|      28|     112|     124|       4
---------------------------------------------------------------------------
  112-  124 (24.97/14.05)	SNFGAEPSQAPSQ
  141-  153 (25.16/14.22)	SNQNYAQSQRPSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.35|      24|      28|     692|     715|       6
---------------------------------------------------------------------------
  692-  715 (43.97/24.19)	ETHPDD..SFTLTD...DSILPSKMVPVT
  718-  746 (33.38/16.54)	ENHTQDanSNSCSDiksESLENSCSVAVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     203.25|      68|     833|     283|     362|       8
---------------------------------------------------------------------------
  283-  362 (96.01/85.66)	NCTKTANVPPIIIDlqDTNSVETNEHHLVV..DPKV..ISISSSSKSrKSRINKKRREATNsiefdvASLDNdcvGKPFIGETK
 1122- 1193 (107.24/64.01)	NVSDSSKISPIRAD..DNVSDQTTTAPLLVlaAPHLnrKHIESDDNS.VSCLRRRRKSEGN......ASSDN...GTKLINEPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     222.93|      74|     834|     514|     594|       9
---------------------------------------------------------------------------
  514-  594 (105.35/74.31)	NTSQN..NEDTSLQKQQcAYKHENYTTStyLKDSIVPILEMKQTVTRVcttdEVKVPKKRGRKKGSKGIDSIIAKEVSLSSEM
 1351- 1426 (117.58/63.18)	NSSQNfvNVGKNMYTQD.RYKEPKGKSA..LKASSIKAEENHLQQEKI....DCKLPSKFQRGDDIKTLAKQVSIKASLEKKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      79.14|      25|     698|     382|     415|      11
---------------------------------------------------------------------------
  364-  380 (20.68/13.33)	.........C...SVCPISSISEIL.SLSN
  389-  415 (35.30/21.81)	MEKImVNANC...SVSKTNNQSQLAdKVPK
 1583- 1603 (23.16/ 6.58)	IEQI.PNAICdvySVYTTNNQS........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.34|      18|      32|     807|     825|      12
---------------------------------------------------------------------------
  807-  825 (27.70/22.35)	DINqTNSNITVALEQFQMP
  842-  859 (31.64/20.27)	NIN.TNSQLSSSLTSCLTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.72|      10|      23|    1024|    1034|      13
---------------------------------------------------------------------------
 1024- 1034 (12.35/12.95)	SLIKERiLKDL
 1049- 1058 (16.37/10.67)	SLLIEK.LKNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.09|      15|      32|     623|     637|      16
---------------------------------------------------------------------------
  623-  637 (24.92/16.44)	GEASQVAEVVI.SPST
  652-  667 (24.17/15.67)	GPESSCSEPSLhSPRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.56|      39|     243|    1194|    1254|      17
---------------------------------------------------------------------------
   37-   79 (58.64/25.48)	ENTTVTKAHlETTRLAKYINQ..LRRRTKCEHLARRAkslLKRWR
 1198- 1238 (64.91/59.18)	ENTRSAQDK.EGFWKSKYRKRkiMERRTLSKHECRRT...IKRLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.99|      20|     672|     670|     689|      18
---------------------------------------------------------------------------
  670-  689 (35.16/21.11)	ACSTNATMSTVATRSTPDKS
 1323- 1342 (32.82/19.19)	ARSSNSTSIVLTIKKTPTKS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08985 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ACGNSKGSSVKPHKTIAKRDTDTVQAVETLI
2) ESDDNSVSCLRRRRKSEGNASSDNGTKLINEPKYYDKENTRS
3) FLDPPDDINNDSGSGGSNTWDEDDRQLRQQVKSKT
4) LSMSNFGAEPSQAPSQATQMRFQSDSANYSLQSNQNYAQSQRPSQFHSQTERNLPNDLSYSRNIDVNSDFLRNTTSNSAPMSSLTKSANPSSTKRLSRNAHEQKQQQPTSFANLL
5) MAISRCTSQRQQPNQNDSSPTPHPKIPIYQT
6) QLQSQQQAFSGPESSCSEPSLHSPRTLDACSTNATMSTVATRSTPDKSIAETHPDDSFTLTDDSILPSKMVPVTPRENHTQDANSNSC
233
1161
1623
109
922
642
263
1202
1657
223
952
729










Molecular Recognition Features






MoRF SequenceStartStop




1) IFDFDF
2) PKIPIYQ
867
945
872
951