<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08954

Description Uncharacterized protein
SequenceMANVRDSDTSLWLHNKLGTSNDSWISGSICSQLNKEVLRNIKECFPDLQTQVKLKLLLSFFHIPRRLVEEWKTELDGVIEVAGLDTELWVSMLAESMKTFPATSSLNTEISDYEDTRPIFTEMVNDLRKLVAKHSDLGMLPLECQYLNKNALVSVVGQQPNPVKHFTIKRKPKSATLRTELLHKSADAQSSLKKASAPTIPLRSRGMPRKMTDTTPLKGIPSRMPTSGFRSPNVNPNNQQRPNLSRTPAGRKDGGIKLIEFTEQPLGYAAAKKRKREQQLEEQARKHEQKAAAAAAADNSSPTSNSAPSNNAATTSVPSTTTTNSFEIKTEPTSLLNRSQSNNIDDGGTLEHKEDIKPEIVDTIASSTHSESISTPEYAPPPLSYTQTTPGGLIDNVGTHSSLEVTKPITSNDVTASSLQQQTQQQKSGNNNNNSNTKRANNAPAVNQQPSQQAQTQPTQIIQQTHTQQHQSSNPNTTTQYILTQQQPTQQQQQHQQTLSTLTAYTQNRQQNTYTATSQTPQTPTSTKILLKTSPSSGVVIRQQQQQQQQQQQSQQTVGNPPPLIATATSTSSAPTLLNIQNVQLPNRPVTIQPASQAAQQQHLQAQLQQQQHTLVSNNTATQQPKLTQVLMQPSGSTGTATVTTTPANANLKNKTIILTQKGVILRNIVGDMYEQIPISNVSGLQTLGSGSTTLMTTAAGPPGLVKTTTVSALPQTQTITLQQQPQSQVTKTQLPTLIPTQQHMIVQQQPQATASLITNPTQQTIIRPVMANVQSGLTTLPGGLTLIQRPGQQPQLVQVQTTPVQQAQQQTQIQRTIITQPAIQQTTQQLRPQQIVLQQKPAATQRLITSTQQIQLQQNAAGGIQRIIQLPQQQQQTQQATQTQQQQQQQQQTQPQQQTAPQRKGLQLTNEHVHEAHEMFRKANRVSRPDKALILGFMAGLRENPRPNSENVIVIKLGEKEEIVQQEDGNTALCLVESHIRLDYNTGEWKTFQNYRRLDQSTQSSTENASSSNNVMQSQNSVVI
Length1025
PositionKinase
OrganismGlossina austeni (Savannah tsetse fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Hippoboscoidea> Glossinidae> Glossina.
Aromaticity0.03
Grand average of hydropathy-0.736
Instability index59.07
Isoelectric point9.64
Molecular weight112890.01
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08954
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     412.00|      49|      49|     787|     835|       1
---------------------------------------------------------------------------
  486-  536 (49.96/10.29)	.QQPTQ.....QQQQHQ........qtlstltAYTQN..RQQNTYTATSQ.T....P..Q...TP.TS...TKI...LLKTSPS
  541-  595 (53.13/11.45)	IRQQQQ.....QQQQQQ..............qSQQTV..GNPPPLIATAT.StssaPTLL...NI.QN...VQLpNRPVTIQPA
  596-  648 (48.91/ 9.91)	SQAAQQqhlqaQLQQQQ...........htlvSNNTA..TQQPKLTQVLM.Q....P..S...GS.TG...TA....TVTTTPA
  652-  700 (39.56/ 6.50)	LKNKTI.....ILTQKG...............VILRNivGDMYE..QIPI.S....NVSG...LQ.TL...GSG.STTLMTTAA
  706-  762 (49.97/10.30)	VKTTTV.....SALPQT...........qtitLQQQP..QSQVTKTQLPTlI....PTQQhmiVQ.QQ...PQA.TASLITNPT
  763-  823 (64.69/15.67)	.QQTI.......IRPVManvqsglttlpggltLIQRP..GQQPQLVQVQT.T....PVQQ...AQ.QQ...TQI.QRTIITQPA
  824-  873 (52.04/11.05)	IQQTTQ.....QLRPQQ.............ivLQQKP..AATQRLI.....T....STQQ...IQlQQnaaGGI.QR.IIQLPQ
  874-  913 (53.73/11.67)	QQQQTQ.....Q......................ATQ..TQQQQQQQQQT.Q....PQQQ..tAP.QR...KGL.Q...LTNEH
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.07|      19|      22|     249|     270|       2
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  244-  262 (29.67/12.48)	LSRTPAGRKDGGIKLIEFT
  266-  284 (29.40/21.41)	LGYAAAKKRKREQQLEEQA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     181.71|      43|      65|     379|     421|       3
---------------------------------------------------------------------------
  329-  370 (55.72/25.51)	KTE....PTSLLNRSQSNNIDDGGT.....LEHKEDIKPEivDTIASSTHS
  379-  421 (75.15/37.31)	APP....PLSYTQTTPGGLIDNVGT..HSSLEVTKPITSN..DVTASSLQQ
  443-  485 (50.84/22.55)	APAvnqqPSQQAQTQPTQIIQQTHTqqHQS...SNP...N..TTTQYILTQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.10|      12|     113|     186|     198|       4
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  186-  198 (17.09/13.03)	ADaQSSLKKASAP
  297-  308 (22.01/12.15)	AD.NSSPTSNSAP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.99|      49|      74|       3|      56|       5
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    3-   56 (71.74/68.51)	NVRDSDTSLWLhNKLGTSNDSWisgSICSQLNKEV..LRNIKECFPDLQTQVKlKL
   80-  130 (78.25/54.87)	EVAGLDTELWV.SMLAESMKTF...PATSSLNTEIsdYEDTRPIFTEMVNDLR.KL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08954 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRTELLHKSADAQSSLKKASAPTIPLRSRGMPRKMTDTTPLKGIPSRMPTSGFRSPNVNPNNQQRPNLSRTPAGRKDGGIKLIEFTEQPLGYAAAKKRKREQQLEEQARKHEQKAAAAAAADNSSPTSNSAPSNNAATTSVPSTTTTNSFEIKTEPTSLLNRSQSNNIDDGGTLEHKEDIKPEIVDTIASSTHSESISTPEYAPPPLSYTQTTPGGLIDNVGTHSSLEVTKPITSNDVTASSLQQQTQQQKSGNNNNNSNTKRANNAPAVNQQPSQQAQTQPTQIIQQTHTQQHQSSNPNTTTQYILTQQQPTQQQQQHQQTLSTLTAYTQNRQQNTYTATSQTPQTPTSTKILLKTSPSSGVVIRQQQQQQQQQQQSQQTVGNPPPLIATATSTSS
2) PTLLNIQNVQLPNRPVTIQPASQAAQQQHLQAQLQQQQHTLVSNNTATQQPKLTQVLMQPSGSTGTATVTTTPANANL
3) QQTQQATQTQQQQQQQQQTQPQQQTAPQRKGLQLTNEHVHEAHEMFRKANRVS
177
575
876
573
652
928










Molecular Recognition Features






MoRF SequenceStartStop




1) IKLIEF
2) LRTELLH
256
177
261
183