<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08920

Description Uncharacterized protein
SequenceMNGMQNTRMGGTWHSSYNMGDRQKVVQILAATLNEIQNTAYNEQKALAMAQEFEKYTFLKSATKDEYVNIIKQKVTQLRMSMRNAPSVANPLAGTGNAVPVVTNGGGAAGGNGNAGNPGYQGQNMAMYAQNRQQQGQQQPVQRLGLASNSLLQQLLNQQQQIPQGMQLTQQQIQQIGQLVRTSPIPPALLGKLPNLPPNVNTWARIYECFQKKIIPTTAMPLIKEVHNAHYQLAVRQHQQQKLTQMRRANGGNMADGLSVGNTGMDAYGGSGQGNMNSMGGNMNAPVNNKISMTAAASKNMANMNTMNNMNAMGNTGNMENMGNAGINGMGAMNGMGAMNGMNNLNGMNSVNNMGGMNNMGNMGNMNNMGNMNNMGNMNNMNATANNTNQMNGMGNMNVNRQVQSNPINMQNLPQMANQVPFRGNQVQNTQLQPQLSMQANVGMQNQSQLAPPHQQRQINQQHPQVKPPNFQITSQDFVKYSADAMALLHKLQQNGSIQLNMDQSQKQSFVRKFISHQKLNAWKAQQKAMAQSSAAGQQDPQQQIQRQQQQNPNQGGANNYLQQQHQQPVQPPASHIPLQLPSLQQLGQPNANPSMGQHMSSAVQQRSISAQGIGADSMASGQNRMTPGSLALVMPALTDEMRMKLRALYEEVSRNNVQLKDVTMLLSDKEKLEVKENMDKITQQYANIDSILSYFYVLTRNTEGTKRLIQMKNMTKNVIDNLKIGVYLAGPDLLEKIRMQYQKHFDYIKEELTRRRAQQARNQSQGQSLSAPVQSQQPRQANQFPVQQFASHSAMQQPMQQNYNGMPQGNIVGGLAQQHPQQQIPQQQYMRSTPNAPLQSQRAGPNASAAQVITSSPSVSNALSPPAHTPSKGMQKTVKKQTTTRRKSVKGSSALPTPAANATTPANLVNSIKTPNSMSTPQVPASQSAKGTPNASSPQNSVKAASNADIVAYTGDVFGTSNVDKKLMSRRDLSKNNPEQFFFAALSNMLELEKNTSSADNVKAKDVKKGLQSPLSPSNSSEWTSGVKAQAIMSAFRQVEFIAELTGCDVLQECAELATHDLREKETTALERKRQAEDDDDMDLLFEDKKLKIEEDIEKRLFAPIELDDWKSWLGGLQET
Length1121
PositionTail
OrganismMetschnikowia bicuspidata var. bicuspidata NRRL YB-4993
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Metschnikowia.
Aromaticity0.04
Grand average of hydropathy-0.731
Instability index48.05
Isoelectric point9.68
Molecular weight123137.72
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08920
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     118.68|      16|      16|     327|     342|       1
---------------------------------------------------------------------------
  321-  340 (28.89/ 9.59)	NM.gnagINGMGAMNGMGAMN
  341-  358 (28.19/ 9.18)	GM...nnLNGMNSVNNMGGMN
  359-  379 (33.04/11.99)	NMgnmgnMNNMGNMNNMGNMN
  380-  398 (28.57/ 9.40)	NM..natANNTNQMNGMGNMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.59|      14|      15|     548|     562|       2
---------------------------------------------------------------------------
  554-  569 (18.93/ 7.68)	NQGGANNYLqQQhQQP
  813-  826 (22.67/ 6.22)	VGGLAQQHP.QQ.QIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.46|      28|      33|     852|     880|       3
---------------------------------------------------------------------------
  852-  880 (45.95/30.32)	QVITSSPSV..SNALS....PPA...HTPSkGMQKTVK
  882-  914 (35.74/18.28)	QTTTRRKSVkgSSALP....TPAanaTTPA.NLVNSIK
  916-  944 (37.77/19.79)	PNSMSTPQV..PASQSakgtPNA...SSP....QNSVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     185.13|      31|      33|     404|     434|       4
---------------------------------------------------------------------------
   91-  124 (26.61/ 6.35)	PLAGTGNAvpvVTNGGGAA......GGNG.......NAGN..PgyQGQN
  125-  160 (30.94/ 8.92)	MAMYAQNR...QQQGQQQPvqrlglASNSL.......LQQ.LL..NQQQ
  161-  201 (26.27/ 6.15)	QIP.QGMQ...LTQQQIQQ.igqlvRTSPIppallgKLPN.LP..PNVN
  419-  452 (41.29/15.06)	QVPFRGNQ...VQNTQLQP..qlsmQAN.V......GMQN.QS..QLAP
  453-  477 (29.25/ 7.92)	..PHQQRQ...I..NQQHP......QVKPP......NFQI.TS..Q..D
  580-  605 (30.77/ 8.82)	QLP....S...LQQLG.QP......NAN.P......SMGQhMS..SAVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.70|      27|      32|     251|     280|       5
---------------------------------------------------------------------------
  252-  279 (47.33/23.36)	GNMADGLSvGNTGMDAYGGSGQGNMNSM
  281-  307 (49.37/20.95)	GNMNAPVN.NKISMTAAASKNMANMNTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.24|      47|     257|     503|     552|       6
---------------------------------------------------------------------------
  503-  552 (78.76/33.72)	DQSQKQSFVRKFISHQ..KLNAWKAQQKAmaqSSAAGQQDPQQQIQRQQQQN
  763-  811 (80.48/29.88)	NQSQGQSLSAPVQSQQprQANQFPVQQFA...SHSAMQQPMQQNYNGMPQGN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.38|      23|      89|    1006|    1029|       8
---------------------------------------------------------------------------
  963- 1004 (24.39/ 9.21)	NVDKKLMSrrDLSKNNPEQFffaalsnmlelekntssADNVK
 1007- 1029 (40.99/20.99)	DVKKGLQS..PLSPSNSSEW.................TSGVK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08920 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EELTRRRAQQARNQSQGQSLSAPVQSQQPRQANQFPVQQFASHSAMQQPMQQNYNGMPQGNIVGGLAQQHPQQQIPQQQYMRSTPNAPLQSQRAGPNASAAQVITSSPSVSNALSPPAHTPSKGMQKTVKKQTTTRRKSVKGSSALPTPAANATTPANLVNSIKTPNSMSTPQVPASQSAKGTPNASSPQNSVKAAS
2) KNTSSADNVKAKDVKKGLQSPLSPSNSSEWT
3) NAWKAQQKAMAQSSAAGQQDPQQQIQRQQQQNPNQGGANNYLQQQHQQPVQPPASHIPLQLPSLQQLGQPNANPSMGQHMSSAVQQRSISAQGIGADSMASGQNRMTPGSLALV
4) NMNNMGNMNNMGNMNNMNATANNTNQMNGMGNMNVNRQVQSNPINMQNLPQMANQVPFRGNQVQNTQLQPQLSMQANVGMQNQSQLAPPHQQRQINQQHPQVKPPNFQITSQD
5) VPVVTNGGGAAGGNGNAGNPGYQGQNMAMYAQNRQQQGQQQPVQR
751
995
521
365
99
947
1025
634
477
143










Molecular Recognition Features






MoRF SequenceStartStop




1) LFEDKKLKIEEDIEKRLFAP
1086
1105