<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08919

Description Uncharacterized protein
SequenceMSRPKNRNSLLAGPGRLAAAARSSKDQLLLLRYSMDRPREPVHALANGAGPRVYPDYQPWAGPPAGAARLAAAECLHNGYLEPPAVPAESLSARTLVHETLLAPDAAAAALLGELLRTLARAYSVRNDTLNRIAGASHAPRPPPRVTMTAPRRDAWLRDLADADVPLARVAARVPHGLRHRLLLDHLCAWQVPEARAVWCVKCVLGAELLLLRRRRDPRDARGLLEWTQQVADHVARESRGPPLPGPRRLRLAYLLRLVRTLYVERLVDRACLLACVARQVRAAPAADGPALHYGVLLTALVLVQTFWRDFVRHDVLARLHAELLLWTHVEVERVPAAAGPGGGALPGALPAALRDSILGLVAGCVARLFRQRSSAFILPAAWLLVGPLLFRVLAQTTPPGAARRRLEAVFRLVDYRNESLLLNMRYSATGPRGAAPRGRPPDDTLAFIGLLDRMDLRGPLAAALRPTPPAAEPARWHTHVRLAVRWGASACRGSRPLAERVLVLCNYIKKSVLQPLTARGSATLKAEFEGELLDSIFALARVPRAALCMHSLAVLVNELCLLRIIAISAYLRKIIACGIFYISSRESELGTATQTDPHISFHLSVLANLPVLNNKQHYLILSKWTPEGEKISSNYARGMEVSRSHVLHGLLSGHFPHDFDAFLAEILLFSVGVKFLLANWLTSQIKSSISQSPKLIHLSPSAIARIYQFYVVTDNLTLFFRAFLRYVLKNEDKVIIFYLDTLHYVGHLLQHHYLLVNFLPGSSPNRISASYELFNLIISAYQDLASREPDSYDFRPLWEFINLSIDTNVAGAAASNQIKLDDPDLERYIFTKDTAESPLKVLLPAPRRNQAYSAELFVQNLNRLLAGDSLPPTADDITDYCRDIGPGNLSVPPEHFSPELDAASTLQVLLQSWYASADQLEERQDCAFSKLTKITMNAMEKRNRVFQTKAAFKSAGILDSSDCARLRRFLIKVIYHRILLFADTISMIAEATDAGGNSKLHPLASSLVFGKEVISHKLFYSESVMFTILQTQYRSTNIEELFRLAIKEMKDSLGSRDSDIWGLHSDVMKETVMQVIINHKDFAISLMFAELPAHVNAKLCCDLLQTDCDVSTIWSCTSLAPLANEFSLPVFQLLLLVLSSNEHLSXAEIGRFTLKFMDACEFAIDSSDSYFGELFNYLEWEDKAKIFNYLELYFLTHRDSLAVWESDFGSNEETNLLMFSRKNLQGVELLPVFKDFFKKFSVSSTESLEMLLDKFEQFSSLLLNILELVDNAAVLKLYSRQLHDIISVFLRLLIIHSASLTKVIAMHDSLHFVFLKNMMLLLNSTYLASGQDKLKILLFDLLFQIKGSLTQALAAPHEDDIMGSSPQVPEANAKTELSPDGATLESTNSAAIMTMSMILNLPEPEMNSYDFGTDEESSPITLDDEEINQSSDVAMANDPNLVLKLKENSVEQEDPFRPTDLKFTKQFRMESVALIEDTTTEINSGCISLSMFGAYTTKENPY
Length1503
PositionKinase
OrganismMetschnikowia bicuspidata var. bicuspidata NRRL YB-4993
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Metschnikowia.
Aromaticity0.08
Grand average of hydropathy0.021
Instability index44.51
Isoelectric point6.62
Molecular weight167361.06
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08919
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     237.76|      47|      47|      35|      81|       1
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   12-   64 (77.87/45.59)	AG..PG........RLAAAARSSKDQL...........lllrysMD.......RPREPVHALANGAGPRVYP.DYQPWA..GPP
   65-  105 (53.77/28.82)	AG..AA........RLAAAECLHNGYL...............epPA.......VPAE...SLS..ARTLV....HETLL..APD
  106-  175 (51.82/27.46)	AA..AAallgellrTLARAYSVRNDTLnriagashaprppprvtMT.......APRRDA.WLRDLADADV.P.LARVAA..RVP
  343-  400 (54.31/29.20)	GGalPG........ALPAALRDSILGL.................VAgcvarlfRQRSSAFILPA.AWLLVGPlLFRVLAqtTPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     197.51|      45|      49|     242|     290|       2
---------------------------------------------------------------------------
  206-  240 (29.46/16.19)	GAELL....LLRRR.............................RD......P.....R..DARGLLEwtqqvadHVARESR........
  246-  290 (80.42/36.02)	GPRRLRLAYLLRLV.............................RTL...YVE.....RLVDRACLLA.......CVARQVRAAPAADGP
  303-  341 (31.35/ 7.92)	............LV.............................QTFwrdFVRhdvlaRL..HAELLL.......WTHVEVERVPAAAGP
  401-  474 (56.29/22.20)	GAARRRLEAVFRLVdyrneslllnmrysatgprgaaprgrppdDTL...AFI.....GLLDRMDLRG.......PLAAALRPTPPAAEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.78|      14|      15|    1229|    1242|       3
---------------------------------------------------------------------------
 1229- 1242 (25.37/13.89)	ELLPVFKDFFKKFS
 1247- 1260 (24.42/13.12)	ESLEMLLDKFEQFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.54|      47|      56|     598|     647|       4
---------------------------------------------------------------------------
  598-  647 (70.36/72.59)	PHiSFHlSVLANLPVLNNKQHYLiLSKWTPEGEKIS.SNYARGMEVSRSHV
  657-  704 (75.18/60.37)	PH.DFD.AFLAEILLFSVGVKFL.LANWLTSQIKSSiSQSPKLIHLSPSAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.09|      21|      56|     489|     533|       5
---------------------------------------------------------------------------
  489-  511 (33.05/60.07)	ASACRGSrpLAERVLVLC........NYIKK
  546-  574 (31.04/ 6.92)	AALCMHS..LAVLVNELCllriiaisAYLRK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.99|      14|      15|     715|     728|       6
---------------------------------------------------------------------------
  715-  728 (24.75/13.57)	DNLTLFFRAFLRYV
  733-  746 (24.24/13.14)	DKVIIFYLDTLHYV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.59|      38|     600|     803|     840|       8
---------------------------------------------------------------------------
  803-  840 (63.97/36.95)	NLSIDTNVAGAAASNQI.......KLDDPDLERYIFTKDTAESPL
 1377- 1421 (59.62/33.96)	ELSPDGATLESTNSAAImtmsmilNLPEPEMNSYDFGTDEESSPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.83|      42|      49|    1017|    1061|      12
---------------------------------------------------------------------------
 1017- 1061 (61.14/52.20)	HKLFYSESVMFTILqtQYRSTNIEELF.....RLAIKEMKDSLGSrDSDI
 1065- 1111 (68.69/46.64)	HSDVMKETVMQVII..NHKDFAISLMFaelpaHVNAKLCCDLLQT.DCDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.93|      18|      25|     853|     876|      15
---------------------------------------------------------------------------
  866-  887 (25.58/22.12)	LAGDSLPPTADditdYCRDIGP
  892-  909 (29.36/ 7.61)	VPPEHFSPELD....AASTLQV
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08919 with Med12 domain of Kingdom Fungi
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