<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08888

Description Cyclin-dependent kinase E-1
SequenceMGDGRGNSGGGGGGNRPAWLQQYELVGKIGEGTYGLVFLARTKQHRKSSIAIKKFKQSKEGDGVSPTAIREIMISHDFIGLDLGGAAQLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHREKLNLSINPYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEHGVVKIADFGLARIYQAPLKTLYENGVVVTIWYRAPELLLGAKHYTTAVDMWAVGCIFAELLTLKPLFQGVEVKATPNPFQLDQLDKIFKVLGHPTTEKWPTLVHLPHWANDQQHIQGHKYENTGLHTFVHLAPKSPAFDLLSKMLEYLIGGGCRKLHGLSSIDQYDPRKRITAAQALEHEYFRMDPLPGRNALVPSQPGEKIPSGNAPPGSVSAQSVAASRAVARQMPAMVGGQRIPAASMAAFNAAAQPGMVGLNPANIPMPRGAAAQQQLRRKDPGVMQNPGYPQQKRRF
Length474
PositionKinase
OrganismAnanas comosus (Pineapple) (Ananas ananas)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Bromeliaceae> Bromelioideae> Ananas.
Aromaticity0.08
Grand average of hydropathy-0.282
Instability index36.62
Isoelectric point9.39
Molecular weight52376.62
Publications
PubMed=27374615

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08888
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.73|      28|      28|     390|     417|       1
---------------------------------------------------------------------------
  390-  417 (48.17/26.91)	PPGSVSAQSVAASRAVARQMPAMVGGQR
  419-  446 (50.56/28.57)	PAASMAAFNAAAQPGMVGLNPANIPMPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.76|      26|      31|      81|     107|       2
---------------------------------------------------------------------------
   81-  107 (38.91/36.29)	LDLGGAAQLLREISHENVVKLvNVHIN
  115-  140 (45.86/37.31)	LAFDYAEHDLYEIIRHHREKL.NLSIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.89|      21|      28|     338|     358|       4
---------------------------------------------------------------------------
  338-  358 (35.25/20.00)	LHGLSSIDQYDPRKRITAAQA
  369-  389 (36.64/21.05)	LPGRNALVPSQPGEKIPSGNA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08888 with CDK8 domain of Kingdom Viridiplantae

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