<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08885

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMEMGGGAAPPQGQQQPPPERRRSGGGAAAGGGAAERGGGAAAEPGVGEDARPRPRQGHLPHPRDFDAYAAPTPPQMFSMVSMELFNIVEDIKKVSKAFTVYPRNVSAENAAILPVMLSSKLLPEMEAEDNTKREQLLYGITNLPKVIADCRKAYGLASRQGPSLVPTLDKVQAAKIQEQENLLRAAVNFGEGLRMPGDQRQLPSSLPSHLVDVLSFGDNTQNFGDNSGSRSTTNWEISSITFGVQCLSCMIYRLPGQHQMQYSQSLSQHFQNRQMQSMQQNMAQNQLNQGSQLRSHLSQFTGAGNNALLNAAQASPNSQMISNISTAMQSQSFCHDAAVFGMGASNPSSMVGMQQQQQSVFGNMPTNVQNLQPGMVTLPNPTQNPNFPQQRQQNQQ
Length396
PositionHead
OrganismAnanas comosus (Pineapple) (Ananas ananas)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Bromeliaceae> Bromelioideae> Ananas.
Aromaticity0.05
Grand average of hydropathy-0.583
Instability index56.81
Isoelectric point7.73
Molecular weight42835.58
Publications
PubMed=27374615

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants
GO - Biological Function
GO - Biological Process
defense response to fungus	GO:0050832	IEA:EnsemblPlants
regulation of flower development	GO:0009909	IEA:EnsemblPlants

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP08885
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.00|      21|      32|       2|      24|       1
---------------------------------------------------------------------------
    2-   24 (39.57/22.84)	EMGGGAA..PPQGQQQPPpeRRRSG
   35-   57 (38.43/16.62)	ERGGGAAaePGVGEDARP..RPRQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.28|      18|      37|      61|      78|       2
---------------------------------------------------------------------------
   61-   78 (36.48/26.82)	HPRDFDAYAAPTPPQMFS
  101-  118 (31.80/22.34)	YPRNVSAENAAILPVMLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.27|      17|      58|     194|     210|       3
---------------------------------------------------------------------------
  194-  210 (34.77/18.43)	RMPGD.QRQLPSSLPSHL
  253-  270 (27.50/13.01)	RLPGQhQMQYSQSLSQHF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.84|      13|      37|     346|     358|       4
---------------------------------------------------------------------------
  346-  358 (24.55/ 9.31)	NPSSMVGMQQQQQ
  384-  396 (24.29/ 9.15)	NPNFPQQRQQNQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      32.13|      11|      18|     122|     139|       5
---------------------------------------------------------------------------
  122-  133 (14.01/12.74)	LPEMEAeDNTKR
  143-  153 (18.12/ 7.77)	LPKVIA.DCRKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.38|      24|      24|     274|     297|       6
---------------------------------------------------------------------------
  274-  297 (42.38/20.46)	QMQSMQQNMAQN..QLNQGSQLRSHL
  299-  324 (36.00/16.38)	QFTGAGNNALLNaaQASPNSQMISNI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP08885 with Med8 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ASNPSSMVGMQQQQQSVFGNMPTNVQNLQPGMVTLPNPTQNPNFPQQRQQNQQ
2) MEMGGGAAPPQGQQQPPPERRRSGGGAAAGGGAAERGGGAAAEPGVGEDARPRPRQGHLPHPRDFDAYAAPT
3) YSQSLSQHFQNRQMQSMQQNMAQNQLNQGSQLRSHLSQ
344
1
262
396
72
299

Molecular Recognition Features

MoRF SequenceStartStop
1) GGAAPPQGQQQPPPERRRSGGGAAAGGGAAERGGGAAAEPGV
5
46