<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP08877

Description Mediator of RNA polymerase II transcription subunit 19a
SequenceMDPEGKKFGRGPRELTGAVDLISHYKLLAHHDFFCKRSLPVSISDTHYLHNVVGDTEIRKGEGMELDQLFQNTPYLRETAARIQQFDLDTLGQALQLRETAPIDLPSAEKGVPTVASKSRSDSKDKERKHKKHKDKDKEKDKEHKKHKHRHKDRSKDKDKEKKKDKSGHHDSGGDHSKKHHEKKRKHESNEDSAEIHKHKRSKSLSRAVED
Length211
PositionHead
OrganismAnanas comosus (Pineapple) (Ananas ananas)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Bromeliaceae> Bromelioideae> Ananas.
Aromaticity0.04
Grand average of hydropathy-1.518
Instability index47.52
Isoelectric point9.49
Molecular weight24374.98
Publications
PubMed=27374615

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP08877
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.21|      21|      21|     133|     153|       1
---------------------------------------------------------------------------
  133-  153 (41.34/13.85)	HKDKDKEKDKEHKKHKHRHKD
  155-  175 (34.87/10.60)	SKDKDKEKKKDKSGHHDSGGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.82|      16|      20|      64|      80|       2
---------------------------------------------------------------------------
   64-   80 (24.85/19.90)	MELDQLFQNTPyLRETA
   86-  101 (26.98/15.89)	FDLDTLGQALQ.LRETA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.73|      13|      16|     180|     192|       3
---------------------------------------------------------------------------
  180-  192 (24.41/10.87)	HHEKKRKHESN..ED
  197-  211 (18.32/ 6.48)	HKHKRSKSLSRavED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP08877 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DLDTLGQALQLRETAPIDLPSAEKGVPTVASKSRSDSKDKERKHKKHKDKDKEKDKEHKKHKHRHKDRSKDKDKEKKKDKSGHHDSGGDHSKKHHEKKRKHESNEDSAEIHKHKRSKSLSRAVED
87
211










Molecular Recognition Features






MoRF SequenceStartStop




1) KDKERKHKKHKDKDKEKDKEHKKHKHRHKDRSKDKDKEKKKDKSGHHDSGGDHSKKHHEKKRKHESNEDSAEIHKHKRSKSLSRAVE
124
210